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GZMA granzyme A [ Pan troglodytes (chimpanzee) ]

Gene ID: 461873, updated on 29-Mar-2024

Summary

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Official Symbol
GZMAprovided by VGNC
Official Full Name
granzyme Aprovided by VGNC
Primary source
VGNC:VGNC:4023
Locus tag
CK820_G0045954
See related
Ensembl:ENSPTRG00000016871
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 4 NC_072402.2 (59551222..59558517, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 5 NC_072403.1 (59980016..59987316, complement)

Chromosome 4 - NC_072402.2Genomic Context describing neighboring genes Neighboring gene cell division cycle 20B Neighboring gene microRNA mir-449a Neighboring gene glutathione peroxidase 8 (putative) Neighboring gene uncharacterized LOC104006447 Neighboring gene granzyme K

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
granzyme A
Names
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
XP_001148261.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    59551222..59558517 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001148261.5 → XP_001148261.1  granzyme A

    See identical proteins and their annotated locations for XP_001148261.1

    UniProtKB/TrEMBL
    A0A2J8JMP1, A0A6D2X7L3, H2QQW5
    Related
    ENSPTRP00000028899.4
    Conserved Domains (1) summary
    cd00190
    Location:29 → 254
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein
Heading Accession and Version

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