HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: HMGCS1provided by VGNC
Official Full Name: 3-hydroxy-3-methylglutaryl-CoA synthase 1provided by VGNC
Primary source: VGNC:VGNC:4035
Locus tag: CK820_G0044218
See related: Ensembl:ENSPTRG00000016845
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 5

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	4	NC_072402.2 (69483550..69508512)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	5	NC_072403.1 (69673174..69698094)

Chromosome 4 - NC_072402.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

SHGC-33119 (e-PCR)
- UniSTS:171026

RH76109 (e-PCR)
- UniSTS:86303

RH98809 (e-PCR)
- UniSTS:86364

G59382 (e-PCR)
- UniSTS:136547

RH99205 (e-PCR)
- UniSTS:84345

RH98561 (e-PCR)
- UniSTS:88699

RH80450 (e-PCR)
- UniSTS:92806

GDB:194504 (e-PCR)
- UniSTS:155793

RH93594 (e-PCR)
- UniSTS:84118

HMGCS1 (e-PCR)
- UniSTS:505768

PMC311006P3 (e-PCR)
- UniSTS:272830

RH102927 (e-PCR)
- UniSTS:97261

PMC327197P1 (e-PCR)
- UniSTS:273139

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables hydroxymethylglutaryl-CoA synthase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in acetyl-CoA metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: hydroxymethylglutaryl-CoA synthase, cytoplasmic

Names: 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble); 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)

XP_003310783.2

EC 2.3.3.10

XP_009447490.1

EC 2.3.3.10

XP_016808832.1

EC 2.3.3.10

XP_063666564.1

EC 2.3.3.10

XP_063666565.1

EC 2.3.3.10

XP_517780.3

EC 2.3.3.10

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

69483550..69508512

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016953343.3 → XP_016808832.1 hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X3

Conserved Domains (1) summary

TIGR01833
Location:13 → 427

HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
XM_003310735.4 → XP_003310783.2 hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X1

UniProtKB/TrEMBL

H2QQU5
XM_517780.7 → XP_517780.3 hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X2

See identical proteins and their annotated locations for XP_517780.3

UniProtKB/TrEMBL

A0A2I3TUA8, A0A2J8JUP0, A0A6D2XV98

Conserved Domains (1) summary

TIGR01833
Location:13 → 469

HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
XM_063810494.1 → XP_063666564.1 hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X2

UniProtKB/TrEMBL

A0A2I3TUA8, A0A2J8JUP0, A0A6D2XV98
XM_009449215.3 → XP_009447490.1 hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X3

See identical proteins and their annotated locations for XP_009447490.1

Conserved Domains (1) summary

TIGR01833
Location:13 → 427

HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
XM_063810495.1 → XP_063666565.1 hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X3