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l(3)07882 lethal (3) 07882 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 46201, updated on 10-May-2024

Summary

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Official Symbol
l(3)07882provided by FlyBase
Official Full Name
lethal (3) 07882provided by FlyBase
Primary source
FLYBASE:FBgn0010926
Locus tag
Dmel_CG5824
See related
AllianceGenome:FB:FBgn0010926
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG5824; Dmel\CG5824
Summary
Predicted to enable snoRNA binding activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be part of Noc4p-Nop14p complex and small-subunit processome. Predicted to be active in nucleolus. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; embryonic/larval fat body; extended germ band embryo; and gut section. Orthologous to human NOP14 (NOP14 nucleolar protein). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See l(3)07882 in Genome Data Viewer
Location:
90B3-90B4; 3-61 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (17535533..17539963, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (13362654..13365685, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44349 Neighboring gene uncharacterized protein Neighboring gene Pyrroline-5-carboxylate reductase-like 2 Neighboring gene Splicing factor 1 Neighboring gene Peroxiredoxin 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The phospho-docking protein 14-3-3 regulates microtubule-associated proteins in oocytes including the chromosomal passenger Borealin. Repton C, et al. PLoS Genet, 2022 Jun. PMID 35666772, Free PMC Article
  2. Functional genomics identifies TOR-regulated genes that control growth and division. Guertin DA, et al. Curr Biol, 2006 May 23. PMID 16713952
  3. The pentameric nucleoplasmin fold is present in Drosophila FKBP39 and a large number of chromatin-related proteins. Edlich-Muth C, et al. J Mol Biol, 2015 May 22. PMID 25813344, Free PMC Article
  4. Cross-species analysis of viral nucleic acid interacting proteins identifies TAOKs as innate immune regulators. Pennemann FL, et al. Nat Commun, 2021 Dec 1. PMID 34853303, Free PMC Article
  5. The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes. Spradling AC, et al. Genetics, 1999 Sep. PMID 10471706, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables snoRNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in maturation of SSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in rRNA processing ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in ribosomal small subunit biogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
part_of Noc4p-Nop14p complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of small-subunit processome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
lethal (3) 07882
Names
CG5824-PA
CG5824-PB
l(3)07882-PA
l(3)07882-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    17535533..17539963 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001316506.1 → NP_001303435.1  lethal (3) 07882, isoform B [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VEJ2
    UniProtKB/TrEMBL
    A0A126GUW2
    Conserved Domains (1) summary
    pfam04147
    Location:30 → 839
    Nop14; Nop14-like family

  2. NM_143783.3 → NP_652040.2  lethal (3) 07882, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_652040.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VEJ2
    UniProtKB/TrEMBL
    A0A126GUW2
    Related
    FBpp0082928
    Conserved Domains (1) summary
    pfam04147
    Location:30 → 839
    Nop14; Nop14-like family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A126GUW2 A0A126GUW2
Q9VEJ2.2 Q9VEJ2

Gene LinkOut

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