ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif 2 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: ADAMTS2provided by VGNC
Official Full Name: ADAM metallopeptidase with thrombospondin type 1 motif 2provided by VGNC
Primary source: VGNC:VGNC:3893
Locus tag: CK820_G0044523
See related: Ensembl:ENSPTRG00000017614
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	4	NC_072402.2 (176575797..176811751, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	5	NC_072403.1 (176598443..176833758, complement)

Chromosome 4 - NC_072402.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

bac51964S (e-PCR)
- UniSTS:181530

bac52194T (e-PCR)
- UniSTS:181559

SHGC-143243 (e-PCR)
- UniSTS:171835

RH44727 (e-PCR)
- UniSTS:41276

SHGC-155422 (e-PCR)
- UniSTS:185419

SGC33801 (e-PCR)
- UniSTS:45172

RH44368 (e-PCR)
- UniSTS:90015

WI-10789 (e-PCR)
- UniSTS:73636

D5S1382 (e-PCR)
- UniSTS:149191

G09291 (e-PCR)
- UniSTS:70652

RH12250 (e-PCR)
- UniSTS:56572

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables metalloendopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in extracellular matrix organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in proteolysis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in collagen-containing extracellular matrix	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: A disintegrin and metalloproteinase with thrombospondin motifs 2

XP_024212635.1

EC 3.4.24.14

XP_054540818.1

EC 3.4.24.14

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

176575797..176811751 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_024356867.3 → XP_024212635.1 A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform X1

UniProtKB/TrEMBL

A0A2J8JTR3, H2QS54, K7DFE1

Conserved Domains (5) summary

smart00209
Location:562 → 614

TSP1; Thrombospondin type 1 repeats

cd04273
Location:264 → 465

ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...

pfam01562
Location:89 → 210

Pep_M12B_propep; Reprolysin family propeptide

pfam05986
Location:721 → 835

ADAM_spacer1; ADAM-TS Spacer 1

pfam08686
Location:1061 → 1091

PLAC; PLAC (protease and lacunin) domain
XM_054684843.2 → XP_054540818.1 A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform X2

UniProtKB/TrEMBL

A0A2I3SNV9, A0A2J8JTV8, A0A6D2W7Y3