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RAB8A RAB8A, member RAS oncogene family [ Pan troglodytes (chimpanzee) ]

Gene ID: 468760, updated on 10-Apr-2024

Summary

Official Symbol
RAB8Aprovided by VGNC
Official Full Name
RAB8A, member RAS oncogene familyprovided by VGNC
Primary source
VGNC:VGNC:7571
Locus tag
CK820_G0026204
See related
Ensembl:ENSPTRG00000010639
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

Location:
chromosome: 19
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 20 NC_072418.2 (18766365..18788565)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 19 NC_072417.1 (18766438..18788607)

Chromosome 20 - NC_072418.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104003283 Neighboring gene tropomyosin 4 Neighboring gene hematopoietic SH2 domain containing Neighboring gene calcium and integrin binding family member 3

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in Golgi vesicle fusion to target membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cilium assembly IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in endocytic recycling IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in neurotransmitter receptor transport to postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein localization to plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein secretion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of exocytosis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in vesicle docking involved in exocytosis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in dendritic spine IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in endosome IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in synaptic vesicle IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in trans-Golgi network transport vesicle IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
ras-related protein Rab-8A
NP_001229300.1
XP_016789602.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001242371.3NP_001229300.1  ras-related protein Rab-8A

    See identical proteins and their annotated locations for NP_001229300.1

    Status: VALIDATED

    Source sequence(s)
    JAQQLN020000020
    UniProtKB/TrEMBL
    A0A2J8LU35, A0A2J8LU80, A0A6D2XR50, G2HFP6
    Related
    ENSPTRP00000018163.2, ENSPTRT00000019630.3
    Conserved Domains (1) summary
    cd01867
    Location:6172
    Rab8_Rab10_Rab13_like; Rab GTPase families 8, 10, 13 (Rab8, Rab10, Rab13)

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072418.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    18766365..18788565
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016934113.3XP_016789602.1  ras-related protein Rab-8A isoform X1