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GHR growth hormone receptor [ Pan troglodytes (chimpanzee) ]

Gene ID: 471560, updated on 29-Mar-2024

Summary

Official Symbol
GHRprovided by VGNC
Official Full Name
growth hormone receptorprovided by VGNC
Primary source
VGNC:VGNC:4013
Locus tag
CK820_G0035951
See related
Ensembl:ENSPTRG00000016836
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

Location:
chromosome: 5
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 4 NC_072402.2 (70071683..70370749, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 5 NC_072403.1 (70260884..70559918, complement)

Chromosome 4 - NC_072402.2Genomic Context describing neighboring genes Neighboring gene selenoprotein P Neighboring gene coiled-coil domain containing 152 Neighboring gene SERPINE1 mRNA-binding protein 1-like Neighboring gene F-box protein 4 Neighboring gene bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like Neighboring gene RAB7A interacting MON1-CCZ1 complex subunit 1

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    70071683..70370749 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_526938.8XP_526938.2  growth hormone receptor isoform X2

    See identical proteins and their annotated locations for XP_526938.2

    UniProtKB/TrEMBL
    A0A2I3T7J6, A0A2J8QAB1, A0A2J8QAB5, A0A6D2WF30, A0A6D2X4B0, H2QQU1
    Related
    ENSPTRP00000028855.2
    Conserved Domains (3) summary
    cd00063
    Location:149250
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam12772
    Location:316617
    GHBP; Growth hormone receptor binding
    cl21522
    Location:49127
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
  2. XM_024356621.3XP_024212389.1  growth hormone receptor isoform X1

    UniProtKB/TrEMBL
    A0A2I3SB56, A0A2I3T7J6, A0A2J8QAA7, A0A2J8QAB5, A0A6D2WF30, A0A6D2X2E9
    Conserved Domains (3) summary
    cd00063
    Location:156257
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam12772
    Location:323624
    GHBP; Growth hormone receptor binding
    cl21522
    Location:56134
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
  3. XM_024356623.3XP_024212391.1  growth hormone receptor isoform X2

    UniProtKB/TrEMBL
    A0A2I3T7J6, A0A2J8QAB1, A0A2J8QAB5, A0A6D2WF30, A0A6D2X4B0, H2QQU1
    Conserved Domains (3) summary
    cd00063
    Location:149250
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam12772
    Location:316617
    GHBP; Growth hormone receptor binding
    cl21522
    Location:49127
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
  4. XM_024356622.2XP_024212390.1  growth hormone receptor isoform X2

    UniProtKB/TrEMBL
    A0A2I3T7J6, A0A2J8QAB1, A0A2J8QAB5, A0A6D2WF30, A0A6D2X4B0, H2QQU1
    Conserved Domains (3) summary
    cd00063
    Location:149250
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam12772
    Location:316617
    GHBP; Growth hormone receptor binding
    cl21522
    Location:49127
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...