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CYP3A43 cytochrome P450 subfamily IIIA polypeptide 43 [ Pan troglodytes (chimpanzee) ]

Gene ID: 472456, updated on 29-Mar-2024

Summary

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Gene symbol
CYP3A43
Gene description
cytochrome P450 subfamily IIIA polypeptide 43
Locus tag
CK820_G0047470
See related
Ensembl:ENSPTRG00000048873
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human all
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Genomic context

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Location:
chromosome: 6
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 6 NC_072404.2 (109289283..109332759)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 7 NC_072405.1 (105636013..105679497)

Chromosome 6 - NC_072404.2Genomic Context describing neighboring genes Neighboring gene cytochrome P450 3A7 Neighboring gene cytochrome P450 family 3 subfamily A member 4 Neighboring gene olfactory receptor family 2 subfamily AE member 1 Neighboring gene tripartite motif containing 4 Neighboring gene gap junction protein gamma 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CYP3 phylogenomics: evidence for positive selection of CYP3A4 and CYP3A7. Qiu H, et al. Pharmacogenet Genomics, 2008 Jan. PMID 18216722

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables testosterone 6-beta-hydroxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in oxidative demethylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in steroid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cytochrome P450 3A43

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072404.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    109289283..109332759
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009453735.3 → XP_009452010.1  cytochrome P450 3A43 isoform X1

    UniProtKB/TrEMBL
    A0A2I3SJ12
    Conserved Domains (1) summary
    pfam00067
    Location:39 → 532
    p450; Cytochrome P450

  2. XM_009453736.3 → XP_009452011.1  cytochrome P450 3A43 isoform X2

    UniProtKB/TrEMBL
    A0A2I3SJ12, A0A2I3TX51, A0A2J8Q0H1, A0A6D2X695
    Related
    ENSPTRP00000093562.1
    Conserved Domains (1) summary
    pfam00067
    Location:39 → 494
    p450; Cytochrome P450

  3. XM_527830.6 → XP_527830.2  cytochrome P450 3A43 isoform X3

    UniProtKB/TrEMBL
    A0A2I3SJ12, A0A2J8Q0E5
    Conserved Domains (1) summary
    pfam00067
    Location:39 → 493
    p450; Cytochrome P450

  4. XM_001142753.4 → XP_001142753.1  cytochrome P450 3A43 isoform X8

    UniProtKB/TrEMBL
    A0A2I3SGM1, A0A2I3SJ12, A0A2J8Q0F8, A0A6D2VWL1
    Related
    ENSPTRP00000076141.1
    Conserved Domains (1) summary
    pfam00067
    Location:39 → 418
    p450; Cytochrome P450

  5. XM_063814790.1 → XP_063670860.1  cytochrome P450 3A43 isoform X4

  6. XM_009453738.3 → XP_009452013.1  cytochrome P450 3A43 isoform X5

    UniProtKB/TrEMBL
    A0A2I3SJ12
    Conserved Domains (1) summary
    pfam00067
    Location:11 → 481
    p450; Cytochrome P450

  7. XM_016957822.2 → XP_016813311.1  cytochrome P450 3A43 isoform X6

    UniProtKB/TrEMBL
    A0A2I3SJ12

  8. XM_009453740.4 → XP_009452015.1  cytochrome P450 3A43 isoform X7

    UniProtKB/TrEMBL
    A0A2I3SJ12
    Conserved Domains (1) summary
    pfam00067
    Location:39 → 431
    p450; Cytochrome P450
Nucleotide Protein
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