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REXO4 REX4 homolog, 3'-5' exonuclease [ Pan troglodytes (chimpanzee) ]

Gene ID: 473152, updated on 29-Mar-2024

Summary

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Official Symbol
REXO4provided by VGNC
Official Full Name
REX4 homolog, 3'-5' exonucleaseprovided by VGNC
Primary source
VGNC:VGNC:53291
Locus tag
CK820_G0012100
See related
Ensembl:ENSPTRG00000023363
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 11 NC_072409.2 (4986177..4998162)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 9 NC_072407.1 (113870552..113882518, complement)

Chromosome 11 - NC_072409.2Genomic Context describing neighboring genes Neighboring gene solute carrier family 2 member 6 Neighboring gene calcium channel flower domain containing 1 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 13 Neighboring gene serine/threonine kinase like domain containing 1 Neighboring gene surfeit 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3'-5' exonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
RNA exonuclease 4
Names
REX4, RNA exonuclease 4 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072409.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    4986177..4998162
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016961996.4 → XP_016817485.1  RNA exonuclease 4 isoform X1

    UniProtKB/TrEMBL
    A0A2J8NAC2, A0A6D2Y010, H2R1M8, K6Z9Z0
    Related
    ENSPTRP00000042599.4
    Conserved Domains (1) summary
    cd06144
    Location:244 → 394
    REX4_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 4, XPMC2, Interferon Stimulated Gene product of 20 kDa, and similar proteins

  2. XM_016961997.4 → XP_016817486.1  RNA exonuclease 4 isoform X3

    UniProtKB/TrEMBL
    A0A2I3SY29, A0A2J8NAB0, A0A2J8NAB3, A0A6D2WB13
    Related
    ENSPTRP00000081492.1
    Conserved Domains (1) summary
    cl10012
    Location:135 → 222
    DnaQ_like_exo; DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily

  3. XM_009457636.5 → XP_009455911.1  RNA exonuclease 4 isoform X2

    Conserved Domains (2) summary
    cd06144
    Location:107 → 257
    REX4_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 4, XPMC2, Interferon Stimulated Gene product of 20 kDa, and similar proteins
    COG0847
    Location:104 → 268
    DnaQ; DNA polymerase III, epsilon subunit or related 3'-5' exonuclease [Replication, recombination and repair]
Nucleotide Protein
Heading Accession and Version

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