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RUFY3 RUN and FYVE domain containing 3 [ Canis lupus familiaris (dog) ]

Gene ID: 475168, updated on 5-Mar-2024

Summary

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Official Symbol
RUFY3provided by VGNC
Official Full Name
RUN and FYVE domain containing 3provided by VGNC
Primary source
VGNC:VGNC:45805
See related
Ensembl:ENSCAFG00845010948
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 13
Exon count:
23
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 13 NC_051817.1 (60813185..60885065)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 13 NC_006595.4 (59741413..59813528)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 13 NC_049234.1 (61067046..61138949)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 13 NC_049273.1 (60427868..60499800)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 13 NC_049754.1 (59919548..59991670)

Chromosome 13 - NC_051817.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119874469 Neighboring gene UTP3 small subunit processome component Neighboring gene uncharacterized LOC106559653 Neighboring gene G-rich RNA sequence binding factor 1 Neighboring gene small nucleolar RNA SNORA62/SNORA6 family

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein RUFY3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051817.1 Reference ROS_Cfam_1.0

    Range
    60813185..60885065
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038685848.1 → XP_038541776.1  protein RUFY3 isoform X7

    UniProtKB/TrEMBL
    A0A8C0NQ18
    Conserved Domains (2) summary
    TIGR02168
    Location:302 → 503
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam02759
    Location:162 → 283
    RUN; RUN domain

  2. XM_038685849.1 → XP_038541777.1  protein RUFY3 isoform X8

    UniProtKB/TrEMBL
    A0A8C0QCG3, A0A8I3RYG5
    Related
    ENSCAFP00845015562.1, ENSCAFT00845019869.1
    Conserved Domains (2) summary
    COG1196
    Location:276 → 482
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam02759
    Location:121 → 242
    RUN; RUN domain

  3. XM_038685843.1 → XP_038541771.1  protein RUFY3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0RYB9
    Conserved Domains (3) summary
    COG1196
    Location:297 → 514
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd15744
    Location:568 → 615
    FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
    pfam02759
    Location:121 → 242
    RUN; RUN domain

  4. XM_038685845.1 → XP_038541773.1  protein RUFY3 isoform X4

    UniProtKB/TrEMBL
    A0A8P0T5E7
    Conserved Domains (2) summary
    TIGR02168
    Location:261 → 523
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam02759
    Location:121 → 242
    RUN; RUN domain

  5. XM_038685847.1 → XP_038541775.1  protein RUFY3 isoform X6

    UniProtKB/TrEMBL
    A0A8P0T5E7
    Conserved Domains (2) summary
    COG1196
    Location:271 → 570
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam02759
    Location:121 → 242
    RUN; RUN domain

  6. XM_038685842.1 → XP_038541770.1  protein RUFY3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RYB9, A0A8P0PAR5
    Conserved Domains (3) summary
    TIGR02168
    Location:261 → 523
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd15744
    Location:579 → 626
    FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
    pfam02759
    Location:121 → 242
    RUN; RUN domain

  7. XM_038685850.1 → XP_038541778.1  protein RUFY3 isoform X9

    UniProtKB/TrEMBL
    A0A8C0LP27, A0A8C0QCG3, A0A8C0RMF9, A0A8P0T293
    Related
    ENSCAFP00845015529.1, ENSCAFT00845019835.1
    Conserved Domains (2) summary
    COG1196
    Location:258 → 464
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam02759
    Location:103 → 224
    RUN; RUN domain

  8. XM_038685844.1 → XP_038541772.1  protein RUFY3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LNC3, A0A8C0NS86, A0A8I3NHR9, A0A8P0P4G3
    Related
    ENSCAFP00845015459.1, ENSCAFT00845019754.1
    Conserved Domains (3) summary
    TIGR02168
    Location:243 → 505
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd15744
    Location:561 → 608
    FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
    pfam02759
    Location:103 → 224
    RUN; RUN domain

  9. XM_038685846.1 → XP_038541774.1  protein RUFY3 isoform X5

    UniProtKB/TrEMBL
    A0A8C0QL97, A0A8I3NTY5
    Related
    ENSCAFP00845015608.1, ENSCAFT00845019925.1
    Conserved Domains (3) summary
    TIGR02168
    Location:213 → 475
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd15744
    Location:531 → 578
    FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
    pfam02759
    Location:73 → 194
    RUN; RUN domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049273.1 Alternate UMICH_Zoey_3.1

    Range
    60427868..60499800
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038493989.1 → XP_038349917.1  protein RUFY3 isoform X7

  2. XM_038493988.1 → XP_038349916.1  protein RUFY3 isoform X15

  3. XM_038493982.1 → XP_038349910.1  protein RUFY3 isoform X11

  4. XM_038493981.1 → XP_038349909.1  protein RUFY3 isoform X10

  5. XM_038493990.1 → XP_038349918.1  protein RUFY3 isoform X8

  6. XM_038493983.1 → XP_038349911.1  protein RUFY3 isoform X12

  7. XM_038493984.1 → XP_038349912.1  protein RUFY3 isoform X13

  8. XM_038493985.1 → XP_038349913.1  protein RUFY3 isoform X1

  9. XM_038493991.1 → XP_038349919.1  protein RUFY3 isoform X9

  10. XM_038493986.1 → XP_038349914.1  protein RUFY3 isoform X3

  11. XM_038493987.1 → XP_038349915.1  protein RUFY3 isoform X14

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049754.1 Alternate UNSW_CanFamBas_1.0

    Range
    59919548..59991670
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038620217.1 → XP_038476145.1  protein RUFY3 isoform X7

  2. XM_038620216.1 → XP_038476144.1  protein RUFY3 isoform X21

  3. XM_038620211.1 → XP_038476139.1  protein RUFY3 isoform X17

  4. XM_038620215.1 → XP_038476143.1  protein RUFY3 isoform X20

  5. XM_038620218.1 → XP_038476146.1  protein RUFY3 isoform X8

    Conserved Domains (2) summary
    COG1196
    Location:276 → 482
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam02759
    Location:121 → 242
    RUN; RUN domain

  6. XM_038620209.1 → XP_038476137.1  protein RUFY3 isoform X16

  7. XM_038620210.1 → XP_038476138.1  protein RUFY3 isoform X1

  8. XM_038620212.1 → XP_038476140.1  protein RUFY3 isoform X18

  9. XM_038620219.1 → XP_038476147.1  protein RUFY3 isoform X9

    Conserved Domains (2) summary
    COG1196
    Location:258 → 464
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam02759
    Location:103 → 224
    RUN; RUN domain

  10. XM_038620213.1 → XP_038476141.1  protein RUFY3 isoform X3

  11. XM_038620214.1 → XP_038476142.1  protein RUFY3 isoform X19

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049234.1 Alternate UU_Cfam_GSD_1.0

    Range
    61067046..61138949
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038556280.1 → XP_038412208.1  protein RUFY3 isoform X7

    UniProtKB/TrEMBL
    A0A8C0NQ18
    Conserved Domains (2) summary
    TIGR02168
    Location:299 → 500
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam02759
    Location:159 → 280
    RUN; RUN domain

  2. XM_038556279.1 → XP_038412207.1  protein RUFY3 isoform X27

    UniProtKB/TrEMBL
    A0A8C0NPZ6
    Conserved Domains (3) summary
    TIGR02168
    Location:179 → 441
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd15744
    Location:502 → 549
    FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
    pfam02759
    Location:39 → 160
    RUN; RUN domain

  3. XM_038556274.1 → XP_038412202.1  protein RUFY3 isoform X23

    UniProtKB/TrEMBL
    A0A8C0RYB9
    Conserved Domains (3) summary
    COG1196
    Location:297 → 514
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd15744
    Location:573 → 620
    FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
    pfam02759
    Location:121 → 242
    RUN; RUN domain

  4. XM_038556278.1 → XP_038412206.1  protein RUFY3 isoform X26

    UniProtKB/TrEMBL
    A0A8P0T5E7

  5. XM_038556281.1 → XP_038412209.1  protein RUFY3 isoform X8

    UniProtKB/TrEMBL
    A0A8C0QCG3, A0A8I3RYG5
    Conserved Domains (2) summary
    COG1196
    Location:276 → 482
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam02759
    Location:121 → 242
    RUN; RUN domain

  6. XM_038556272.1 → XP_038412200.1  protein RUFY3 isoform X22

    UniProtKB/TrEMBL
    A0A8C0RYB9

  7. XM_038556273.1 → XP_038412201.1  protein RUFY3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RYB9, A0A8P0PAR5
    Conserved Domains (3) summary
    TIGR02168
    Location:261 → 523
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd15744
    Location:579 → 626
    FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
    pfam02759
    Location:121 → 242
    RUN; RUN domain

  8. XM_038556275.1 → XP_038412203.1  protein RUFY3 isoform X24

    UniProtKB/TrEMBL
    A0A8C0NS86

  9. XM_038556282.1 → XP_038412210.1  protein RUFY3 isoform X9

    UniProtKB/TrEMBL
    A0A8C0LP27, A0A8C0QCG3, A0A8C0RMF9, A0A8P0T293
    Conserved Domains (2) summary
    COG1196
    Location:258 → 464
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam02759
    Location:103 → 224
    RUN; RUN domain

  10. XM_038556276.1 → XP_038412204.1  protein RUFY3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LNC3, A0A8C0NS86, A0A8I3NHR9, A0A8P0P4G3
    Conserved Domains (3) summary
    TIGR02168
    Location:243 → 505
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd15744
    Location:561 → 608
    FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
    pfam02759
    Location:103 → 224
    RUN; RUN domain

  11. XM_038556277.1 → XP_038412205.1  protein RUFY3 isoform X25

    UniProtKB/TrEMBL
    A0A8C0QL97

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006595.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    59741413..59813528
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003431831.5 → XP_003431879.3  protein RUFY3 isoform X7

    UniProtKB/TrEMBL
    A0A8C0NQ18
    Conserved Domains (2) summary
    TIGR02168
    Location:301 → 502
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam02759
    Location:161 → 282
    RUN; RUN domain

  2. XM_022427080.2 → XP_022282788.2  protein RUFY3 isoform X28

    UniProtKB/TrEMBL
    A0A8C0NPZ6
    Conserved Domains (3) summary
    TIGR02168
    Location:179 → 441
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd15744
    Location:497 → 544
    FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
    pfam02759
    Location:39 → 160
    RUN; RUN domain

  3. XM_038430801.1 → XP_038286729.1  protein RUFY3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0RYB9
    Conserved Domains (3) summary
    COG1196
    Location:297 → 514
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd15744
    Location:568 → 615
    FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
    pfam02759
    Location:121 → 242
    RUN; RUN domain

  4. XM_014118842.3 → XP_013974317.1  protein RUFY3 isoform X8

    UniProtKB/TrEMBL
    A0A8C0QCG3, A0A8I3RYG5
    Conserved Domains (2) summary
    COG1196
    Location:276 → 482
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam02759
    Location:121 → 242
    RUN; RUN domain

  5. XM_038430802.1 → XP_038286730.1  protein RUFY3 isoform X4

    UniProtKB/TrEMBL
    A0A8P0T5E7
    Conserved Domains (2) summary
    TIGR02168
    Location:261 → 523
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam02759
    Location:121 → 242
    RUN; RUN domain

  6. XM_038430804.1 → XP_038286732.1  protein RUFY3 isoform X6

    UniProtKB/TrEMBL
    A0A8P0T5E7
    Conserved Domains (2) summary
    COG1196
    Location:271 → 570
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam02759
    Location:121 → 242
    RUN; RUN domain

  7. XM_005628273.4 → XP_005628330.1  protein RUFY3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RYB9, A0A8P0PAR5
    Conserved Domains (3) summary
    TIGR02168
    Location:261 → 523
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd15744
    Location:579 → 626
    FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
    pfam02759
    Location:121 → 242
    RUN; RUN domain

  8. XM_532400.7 → XP_532400.3  protein RUFY3 isoform X9

    See identical proteins and their annotated locations for XP_532400.3

    UniProtKB/TrEMBL
    A0A8C0LP27, A0A8C0QCG3, A0A8C0RMF9, A0A8P0T293
    Conserved Domains (2) summary
    COG1196
    Location:258 → 464
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam02759
    Location:103 → 224
    RUN; RUN domain

  9. XM_857342.6 → XP_862435.1  protein RUFY3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LNC3, A0A8C0NS86, A0A8I3NHR9, A0A8P0P4G3
    Conserved Domains (3) summary
    TIGR02168
    Location:243 → 505
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd15744
    Location:561 → 608
    FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
    pfam02759
    Location:103 → 224
    RUN; RUN domain

  10. XM_022427084.1 → XP_022282792.1  protein RUFY3 isoform X5

    UniProtKB/TrEMBL
    A0A8C0QL97, A0A8P0T020
    Conserved Domains (3) summary
    cd15744
    Location:531 → 578
    FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
    pfam02759
    Location:73 → 194
    RUN; RUN domain
    cl25732
    Location:213 → 470
    SMC_N; RecF/RecN/SMC N terminal domain
Nucleotide Protein
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