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OTUD4 OTU deubiquitinase 4 [ Canis lupus familiaris (dog) ]

Gene ID: 475455, updated on 5-Mar-2024

Summary

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Official Symbol
OTUD4provided by VGNC
Official Full Name
OTU deubiquitinase 4provided by VGNC
Primary source
VGNC:VGNC:44186
See related
Ensembl:ENSCAFG00845011956
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 15
Exon count:
23
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (44485491..44530755, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (44208727..44253896, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 15 NC_049236.1 (44109586..44154745, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (43758510..43803683, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 15 NC_049756.1 (43845139..43890348, complement)

Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119869295 Neighboring gene anaphase promoting complex subunit 10 Neighboring gene ATP binding cassette subfamily E member 1 Neighboring gene SMAD family member 1 Neighboring gene uncharacterized LOC119869406

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables K63-linked deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of interleukin-1-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein deubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of protein K48-linked deubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
OTU domain-containing protein 4
Names
OTU domain containing 4
XP_022259163.1
XP_022259164.1
XP_022259165.1
XP_022259166.1
XP_022259167.1
XP_022259168.1
XP_038352434.1
XP_038352435.1
XP_038352436.1
XP_038352437.1
XP_038352438.1
XP_038352439.1
XP_038352440.1
XP_038414830.1
XP_038414831.1
XP_038414832.1
XP_038414833.1
XP_038414834.1
XP_038414835.1
XP_038414836.1
XP_038478755.1
XP_038478756.1
XP_038478757.1
XP_038478758.1
XP_038478759.1
XP_038478760.1
XP_038478761.1
XP_038544425.1
XP_038544426.1
XP_038544427.1
XP_038544428.1
XP_038544429.1
XP_038544430.1
XP_038544431.1
XP_532680.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051819.1 Reference ROS_Cfam_1.0

    Range
    44485491..44530755 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038688499.1 → XP_038544427.1  OTU domain-containing protein 4 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LJL2
    Conserved Domains (4) summary
    PHA03247
    Location:525 → 873
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:886 → 1090
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:257 → 315
    Tudor_SF; Tudor domain superfamily
    cl19932
    Location:42 → 104
    OTU; OTU-like cysteine protease

  2. XM_038688498.1 → XP_038544426.1  OTU domain-containing protein 4 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LJL2, A0A8C0MTT5, A0A8I3NMT1
    Related
    ENSCAFP00845016746.1, ENSCAFT00845021291.1
    Conserved Domains (4) summary
    PHA03247
    Location:542 → 890
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:903 → 1107
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:274 → 332
    Tudor_SF; Tudor domain superfamily
    cl19932
    Location:42 → 121
    OTU; OTU-like cysteine protease

  3. XM_038688497.1 → XP_038544425.1  OTU domain-containing protein 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LJL2, A0A8C0QIY6
    Conserved Domains (4) summary
    PHA03247
    Location:563 → 911
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:924 → 1128
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:295 → 353
    Tudor_SF; Tudor domain superfamily
    cl19932
    Location:42 → 142
    OTU; OTU-like cysteine protease

  4. XM_038688503.1 → XP_038544431.1  OTU domain-containing protein 4 isoform X5

    UniProtKB/TrEMBL
    A0A8I3NA86, A0A8P0SCW9
    Conserved Domains (3) summary
    PHA03247
    Location:460 → 808
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:821 → 1025
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:192 → 250
    Tudor_SF; Tudor domain superfamily

  5. XM_038688500.1 → XP_038544428.1  OTU domain-containing protein 4 isoform X4

    UniProtKB/TrEMBL
    A0A8I3NA86, A0A8P0SCW9
    Related
    ENSCAFP00845016849.1, ENSCAFT00845021439.1
    Conserved Domains (3) summary
    PHA03247
    Location:498 → 846
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:859 → 1063
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:230 → 288
    Tudor_SF; Tudor domain superfamily

  6. XM_038688502.1 → XP_038544430.1  OTU domain-containing protein 4 isoform X4

    UniProtKB/TrEMBL
    A0A8I3NA86, A0A8P0SCW9
    Conserved Domains (3) summary
    PHA03247
    Location:498 → 846
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:859 → 1063
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:230 → 288
    Tudor_SF; Tudor domain superfamily

  7. XM_038688501.1 → XP_038544429.1  OTU domain-containing protein 4 isoform X4

    UniProtKB/TrEMBL
    A0A8I3NA86, A0A8P0SCW9
    Conserved Domains (3) summary
    PHA03247
    Location:498 → 846
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:859 → 1063
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:230 → 288
    Tudor_SF; Tudor domain superfamily

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049275.1 Alternate UMICH_Zoey_3.1

    Range
    43758510..43803683 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038496508.1 → XP_038352436.1  OTU domain-containing protein 4 isoform X3

    Conserved Domains (4) summary
    PHA03247
    Location:525 → 873
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:886 → 1090
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:257 → 315
    Tudor_SF; Tudor domain superfamily
    cl19932
    Location:42 → 104
    OTU; OTU-like cysteine protease

  2. XM_038496507.1 → XP_038352435.1  OTU domain-containing protein 4 isoform X2

    Conserved Domains (4) summary
    PHA03247
    Location:542 → 890
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:903 → 1107
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:274 → 332
    Tudor_SF; Tudor domain superfamily
    cl19932
    Location:42 → 121
    OTU; OTU-like cysteine protease

  3. XM_038496506.1 → XP_038352434.1  OTU domain-containing protein 4 isoform X1

    Conserved Domains (4) summary
    PHA03247
    Location:563 → 911
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:924 → 1128
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:295 → 353
    Tudor_SF; Tudor domain superfamily
    cl19932
    Location:42 → 142
    OTU; OTU-like cysteine protease

  4. XM_038496512.1 → XP_038352440.1  OTU domain-containing protein 4 isoform X5

    Conserved Domains (3) summary
    PHA03247
    Location:460 → 808
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:821 → 1025
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:192 → 250
    Tudor_SF; Tudor domain superfamily

  5. XM_038496509.1 → XP_038352437.1  OTU domain-containing protein 4 isoform X4

    Conserved Domains (3) summary
    PHA03247
    Location:498 → 846
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:859 → 1063
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:230 → 288
    Tudor_SF; Tudor domain superfamily

  6. XM_038496511.1 → XP_038352439.1  OTU domain-containing protein 4 isoform X4

    Conserved Domains (3) summary
    PHA03247
    Location:498 → 846
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:859 → 1063
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:230 → 288
    Tudor_SF; Tudor domain superfamily

  7. XM_038496510.1 → XP_038352438.1  OTU domain-containing protein 4 isoform X4

    Conserved Domains (3) summary
    PHA03247
    Location:498 → 846
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:859 → 1063
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:230 → 288
    Tudor_SF; Tudor domain superfamily

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049756.1 Alternate UNSW_CanFamBas_1.0

    Range
    43845139..43890348 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038622829.1 → XP_038478757.1  OTU domain-containing protein 4 isoform X3

    Conserved Domains (4) summary
    PHA03247
    Location:525 → 873
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:886 → 1090
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:257 → 315
    Tudor_SF; Tudor domain superfamily
    cl19932
    Location:42 → 104
    OTU; OTU-like cysteine protease

  2. XM_038622828.1 → XP_038478756.1  OTU domain-containing protein 4 isoform X2

    Conserved Domains (4) summary
    PHA03247
    Location:542 → 890
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:903 → 1107
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:274 → 332
    Tudor_SF; Tudor domain superfamily
    cl19932
    Location:42 → 121
    OTU; OTU-like cysteine protease

  3. XM_038622827.1 → XP_038478755.1  OTU domain-containing protein 4 isoform X1

    Conserved Domains (4) summary
    PHA03247
    Location:563 → 911
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:924 → 1128
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:295 → 353
    Tudor_SF; Tudor domain superfamily
    cl19932
    Location:42 → 142
    OTU; OTU-like cysteine protease

  4. XM_038622833.1 → XP_038478761.1  OTU domain-containing protein 4 isoform X5

    Conserved Domains (3) summary
    PHA03247
    Location:460 → 808
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:821 → 1025
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:192 → 250
    Tudor_SF; Tudor domain superfamily

  5. XM_038622830.1 → XP_038478758.1  OTU domain-containing protein 4 isoform X4

    Conserved Domains (3) summary
    PHA03247
    Location:498 → 846
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:859 → 1063
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:230 → 288
    Tudor_SF; Tudor domain superfamily

  6. XM_038622832.1 → XP_038478760.1  OTU domain-containing protein 4 isoform X4

    Conserved Domains (3) summary
    PHA03247
    Location:498 → 846
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:859 → 1063
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:230 → 288
    Tudor_SF; Tudor domain superfamily

  7. XM_038622831.1 → XP_038478759.1  OTU domain-containing protein 4 isoform X4

    Conserved Domains (3) summary
    PHA03247
    Location:498 → 846
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:859 → 1063
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:230 → 288
    Tudor_SF; Tudor domain superfamily

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049236.1 Alternate UU_Cfam_GSD_1.0

    Range
    44109586..44154745 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038558904.1 → XP_038414832.1  OTU domain-containing protein 4 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LJL2
    Conserved Domains (4) summary
    PHA03247
    Location:525 → 873
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:886 → 1090
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:257 → 315
    Tudor_SF; Tudor domain superfamily
    cl19932
    Location:42 → 104
    OTU; OTU-like cysteine protease

  2. XM_038558903.1 → XP_038414831.1  OTU domain-containing protein 4 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LJL2, A0A8C0MTT5, A0A8I3NMT1
    Conserved Domains (4) summary
    PHA03247
    Location:542 → 890
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:903 → 1107
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:274 → 332
    Tudor_SF; Tudor domain superfamily
    cl19932
    Location:42 → 121
    OTU; OTU-like cysteine protease

  3. XM_038558902.1 → XP_038414830.1  OTU domain-containing protein 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LJL2, A0A8C0QIY6
    Conserved Domains (4) summary
    PHA03247
    Location:563 → 911
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:924 → 1128
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:295 → 353
    Tudor_SF; Tudor domain superfamily
    cl19932
    Location:42 → 142
    OTU; OTU-like cysteine protease

  4. XM_038558908.1 → XP_038414836.1  OTU domain-containing protein 4 isoform X5

    UniProtKB/TrEMBL
    A0A8I3NA86, A0A8P0SCW9
    Conserved Domains (3) summary
    PHA03247
    Location:460 → 808
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:821 → 1025
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:192 → 250
    Tudor_SF; Tudor domain superfamily

  5. XM_038558905.1 → XP_038414833.1  OTU domain-containing protein 4 isoform X4

    UniProtKB/TrEMBL
    A0A8I3NA86, A0A8P0SCW9
    Conserved Domains (3) summary
    PHA03247
    Location:498 → 846
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:859 → 1063
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:230 → 288
    Tudor_SF; Tudor domain superfamily

  6. XM_038558907.1 → XP_038414835.1  OTU domain-containing protein 4 isoform X4

    UniProtKB/TrEMBL
    A0A8I3NA86, A0A8P0SCW9
    Conserved Domains (3) summary
    PHA03247
    Location:498 → 846
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:859 → 1063
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:230 → 288
    Tudor_SF; Tudor domain superfamily

  7. XM_038558906.1 → XP_038414834.1  OTU domain-containing protein 4 isoform X4

    UniProtKB/TrEMBL
    A0A8I3NA86, A0A8P0SCW9
    Conserved Domains (3) summary
    PHA03247
    Location:498 → 846
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:859 → 1063
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:230 → 288
    Tudor_SF; Tudor domain superfamily

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    44208727..44253896 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022403456.2 → XP_022259164.1  OTU domain-containing protein 4 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LJL2
    Conserved Domains (4) summary
    PHA03247
    Location:525 → 873
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:886 → 1090
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:257 → 315
    Tudor_SF; Tudor domain superfamily
    cl19932
    Location:42 → 104
    OTU; OTU-like cysteine protease

  2. XM_532680.7 → XP_532680.3  OTU domain-containing protein 4 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LJL2, A0A8C0MTT5, A0A8I3NMT1
    Conserved Domains (4) summary
    PHA03247
    Location:542 → 890
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:903 → 1107
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:274 → 332
    Tudor_SF; Tudor domain superfamily
    cl19932
    Location:42 → 121
    OTU; OTU-like cysteine protease

  3. XM_022403455.2 → XP_022259163.1  OTU domain-containing protein 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LJL2, A0A8C0QIY6
    Conserved Domains (4) summary
    PHA03247
    Location:563 → 911
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:924 → 1128
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:295 → 353
    Tudor_SF; Tudor domain superfamily
    cl19932
    Location:42 → 142
    OTU; OTU-like cysteine protease

  4. XM_022403460.2 → XP_022259168.1  OTU domain-containing protein 4 isoform X5

    UniProtKB/TrEMBL
    A0A8I3NA86, A0A8P0SCW9
    Conserved Domains (3) summary
    PHA03247
    Location:460 → 808
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:821 → 1025
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:192 → 250
    Tudor_SF; Tudor domain superfamily

  5. XM_022403457.2 → XP_022259165.1  OTU domain-containing protein 4 isoform X4

    UniProtKB/TrEMBL
    A0A8I3NA86, A0A8P0SCW9
    Conserved Domains (3) summary
    PHA03247
    Location:498 → 846
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:859 → 1063
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:230 → 288
    Tudor_SF; Tudor domain superfamily

  6. XM_022403459.2 → XP_022259167.1  OTU domain-containing protein 4 isoform X4

    UniProtKB/TrEMBL
    A0A8I3NA86, A0A8P0SCW9
    Conserved Domains (3) summary
    PHA03247
    Location:498 → 846
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:859 → 1063
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:230 → 288
    Tudor_SF; Tudor domain superfamily

  7. XM_022403458.2 → XP_022259166.1  OTU domain-containing protein 4 isoform X4

    UniProtKB/TrEMBL
    A0A8I3NA86, A0A8P0SCW9
    Conserved Domains (3) summary
    PHA03247
    Location:498 → 846
    PHA03247; large tegument protein UL36; Provisional
    PRK12678
    Location:859 → 1063
    PRK12678; transcription termination factor Rho; Provisional
    cl02573
    Location:230 → 288
    Tudor_SF; Tudor domain superfamily
Nucleotide Protein
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