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TBX3 T-box transcription factor 3 [ Canis lupus familiaris (dog) ]

Gene ID: 477494, updated on 5-Mar-2024

Summary

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Official Symbol
TBX3provided by VGNC
Official Full Name
T-box transcription factor 3provided by VGNC
Primary source
VGNC:VGNC:47174
See related
Ensembl:ENSCAFG00845024752
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 26
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 26 NC_051830.1 (11953157..11967841, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 26 NC_006608.4 (11753296..11767965, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 26 NC_049247.1 (12026728..12041404, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 26 NC_049286.1 (11914521..11929199, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 26 NC_049767.1 (11977110..11991787, complement)

Chromosome 26 - NC_051830.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111092531 Neighboring gene T-box transcription factor 5 Neighboring gene uncharacterized LOC119866157 Neighboring gene uncharacterized LOC119866158 Neighboring gene uncharacterized LOC111092563 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cardiac chamber development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell fate specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in central nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heart looping IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
T-box transcription factor TBX3
Names
T-box 3 (ulnar mammary syndrome)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051830.1 Reference ROS_Cfam_1.0

    Range
    11953157..11967841 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038436803.1 → XP_038292731.1  T-box transcription factor TBX3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KZP4, A0A8C0RTW0, A0A8C0Z6F5, A0A8I3Q583
    Related
    ENSCAFP00845034318.1, ENSCAFT00845043796.1
    Conserved Domains (2) summary
    pfam12598
    Location:323 → 403
    TBX; T-box transcription factor
    cd20188
    Location:104 → 305
    T-box_TBX2_3-like; DNA-binding domain of T-box transcription factor 2 and 3, and related T-box proteins

  2. XM_038436804.1 → XP_038292732.1  T-box transcription factor TBX3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PGV1, A0A8C0R3A2, A0A8C0TU81, A0A8I3PSV4
    Related
    ENSCAFP00845034385.1, ENSCAFT00845043876.1
    Conserved Domains (2) summary
    pfam12598
    Location:303 → 383
    TBX; T-box transcription factor
    cd20188
    Location:104 → 285
    T-box_TBX2_3-like; DNA-binding domain of T-box transcription factor 2 and 3, and related T-box proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049286.1 Alternate UMICH_Zoey_3.1

    Range
    11914521..11929199 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038511710.1 → XP_038367638.1  T-box transcription factor TBX3 isoform X1

    Conserved Domains (2) summary
    pfam12598
    Location:323 → 403
    TBX; T-box transcription factor
    cd20188
    Location:104 → 305
    T-box_TBX2_3-like; DNA-binding domain of T-box transcription factor 2 and 3, and related T-box proteins

  2. XM_038511711.1 → XP_038367639.1  T-box transcription factor TBX3 isoform X2

    Conserved Domains (2) summary
    pfam12598
    Location:303 → 383
    TBX; T-box transcription factor
    cd20188
    Location:104 → 285
    T-box_TBX2_3-like; DNA-binding domain of T-box transcription factor 2 and 3, and related T-box proteins

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049767.1 Alternate UNSW_CanFamBas_1.0

    Range
    11977110..11991787 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038639390.1 → XP_038495318.1  T-box transcription factor TBX3 isoform X1

    Conserved Domains (2) summary
    pfam12598
    Location:323 → 403
    TBX; T-box transcription factor
    cd20188
    Location:104 → 305
    T-box_TBX2_3-like; DNA-binding domain of T-box transcription factor 2 and 3, and related T-box proteins

  2. XM_038639391.1 → XP_038495319.1  T-box transcription factor TBX3 isoform X2

    Conserved Domains (2) summary
    pfam12598
    Location:303 → 383
    TBX; T-box transcription factor
    cd20188
    Location:104 → 285
    T-box_TBX2_3-like; DNA-binding domain of T-box transcription factor 2 and 3, and related T-box proteins

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049247.1 Alternate UU_Cfam_GSD_1.0

    Range
    12026728..12041404 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038575203.1 → XP_038431131.1  T-box transcription factor TBX3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KZP4, A0A8C0RTW0, A0A8C0Z6F5, A0A8I3Q583
    Conserved Domains (2) summary
    pfam12598
    Location:323 → 403
    TBX; T-box transcription factor
    cd20188
    Location:104 → 305
    T-box_TBX2_3-like; DNA-binding domain of T-box transcription factor 2 and 3, and related T-box proteins

  2. XM_038575204.1 → XP_038431132.1  T-box transcription factor TBX3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PGV1, A0A8C0R3A2, A0A8C0TU81, A0A8I3PSV4
    Conserved Domains (2) summary
    pfam12598
    Location:303 → 383
    TBX; T-box transcription factor
    cd20188
    Location:104 → 285
    T-box_TBX2_3-like; DNA-binding domain of T-box transcription factor 2 and 3, and related T-box proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006608.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    11753296..11767965 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038459227.1 → XP_038315155.1  T-box transcription factor TBX3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KZP4, A0A8C0RTW0, A0A8C0Z6F5, A0A8I3Q583
    Conserved Domains (2) summary
    pfam12598
    Location:323 → 403
    TBX; T-box transcription factor
    cd20188
    Location:104 → 305
    T-box_TBX2_3-like; DNA-binding domain of T-box transcription factor 2 and 3, and related T-box proteins

  2. XM_038459228.1 → XP_038315156.1  T-box transcription factor TBX3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PGV1, A0A8C0R3A2, A0A8C0TU81, A0A8I3PSV4
    Conserved Domains (2) summary
    pfam12598
    Location:303 → 383
    TBX; T-box transcription factor
    cd20188
    Location:104 → 285
    T-box_TBX2_3-like; DNA-binding domain of T-box transcription factor 2 and 3, and related T-box proteins
Nucleotide Protein
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