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ACVRL1 activin A receptor like type 1 [ Canis lupus familiaris (dog) ]

Gene ID: 477603, updated on 5-Mar-2024

Summary

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Official Symbol
ACVRL1provided by VGNC
Official Full Name
activin A receptor like type 1provided by VGNC
Primary source
VGNC:VGNC:37566
See related
Ensembl:ENSCAFG00845027472
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 27
Exon count:
11
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 27 NC_051831.1 (3072148..3086549, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 27 NC_006609.4 (43166746..43181176)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 27 NC_049248.1 (43565141..43579587)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 27 NC_049287.1 (3088717..3103128, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 27 NC_049768.1 (3075021..3089444, complement)

Chromosome 27 - NC_051831.1Genomic Context describing neighboring genes Neighboring gene trafficking regulator and scaffold protein tamalin Neighboring gene activin A receptor type 1B Neighboring gene uncharacterized LOC119866360 Neighboring gene uncharacterized LOC102153499 Neighboring gene ankyrin repeat domain 33

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables SMAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transforming growth factor beta receptor activity, type I IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to growth factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in dorsal/ventral pattern formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heart development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transforming growth factor beta receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of BMP receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase receptor R3
XP_013964123.2
XP_022266779.2
XP_038294058.1
XP_038294059.1
XP_038368752.1
XP_038368753.1
XP_038433645.1
XP_038433646.1
XP_038496513.1
XP_038496514.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051831.1 Reference ROS_Cfam_1.0

    Range
    3072148..3086549 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038438131.1 → XP_038294059.1  serine/threonine-protein kinase receptor R3 isoform X2

    UniProtKB/TrEMBL
    A0A7I8AUV5, A0A7I8AVG8, A0A8C0JIT4, A0A8P0SR48
    Related
    ENSCAFP00845038005.1, ENSCAFT00845048446.1
    Conserved Domains (2) summary
    cd14142
    Location:197 → 494
    STKc_ACVR1_ALK1; Catalytic domain of the Serine/Threonine Kinases, Activin Type I Receptor and Activin receptor-Like Kinase 1
    pfam08515
    Location:174 → 201
    TGF_beta_GS; Transforming growth factor beta type I GS-motif

  2. XM_038438130.1 → XP_038294058.1  serine/threonine-protein kinase receptor R3 isoform X1

    UniProtKB/TrEMBL
    A0A7I8AVG8
    Conserved Domains (2) summary
    cd14142
    Location:216 → 513
    STKc_ACVR1_ALK1; Catalytic domain of the Serine/Threonine Kinases, Activin Type I Receptor and Activin receptor-Like Kinase 1
    pfam08515
    Location:193 → 220
    TGF_beta_GS; Transforming growth factor beta type I GS-motif

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049287.1 Alternate UMICH_Zoey_3.1

    Range
    3088717..3103128 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038512825.1 → XP_038368753.1  serine/threonine-protein kinase receptor R3 isoform X2

    Conserved Domains (2) summary
    cd14142
    Location:197 → 494
    STKc_ACVR1_ALK1; Catalytic domain of the Serine/Threonine Kinases, Activin Type I Receptor and Activin receptor-Like Kinase 1
    pfam08515
    Location:174 → 201
    TGF_beta_GS; Transforming growth factor beta type I GS-motif

  2. XM_038512824.1 → XP_038368752.1  serine/threonine-protein kinase receptor R3 isoform X1

    Conserved Domains (2) summary
    cd14142
    Location:216 → 513
    STKc_ACVR1_ALK1; Catalytic domain of the Serine/Threonine Kinases, Activin Type I Receptor and Activin receptor-Like Kinase 1
    pfam08515
    Location:193 → 220
    TGF_beta_GS; Transforming growth factor beta type I GS-motif

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049768.1 Alternate UNSW_CanFamBas_1.0

    Range
    3075021..3089444 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038640586.1 → XP_038496514.1  serine/threonine-protein kinase receptor R3 isoform X2

    Conserved Domains (2) summary
    cd14142
    Location:197 → 494
    STKc_ACVR1_ALK1; Catalytic domain of the Serine/Threonine Kinases, Activin Type I Receptor and Activin receptor-Like Kinase 1
    pfam08515
    Location:174 → 201
    TGF_beta_GS; Transforming growth factor beta type I GS-motif

  2. XM_038640585.1 → XP_038496513.1  serine/threonine-protein kinase receptor R3 isoform X1

    Conserved Domains (2) summary
    cd14142
    Location:216 → 513
    STKc_ACVR1_ALK1; Catalytic domain of the Serine/Threonine Kinases, Activin Type I Receptor and Activin receptor-Like Kinase 1
    pfam08515
    Location:193 → 220
    TGF_beta_GS; Transforming growth factor beta type I GS-motif

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049248.1 Alternate UU_Cfam_GSD_1.0

    Range
    43565141..43579587
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038577718.1 → XP_038433646.1  serine/threonine-protein kinase receptor R3 isoform X2

    UniProtKB/TrEMBL
    A0A7I8AUV5, A0A7I8AVG8, A0A8C0JIT4, A0A8P0SR48
    Conserved Domains (2) summary
    cd14142
    Location:197 → 494
    STKc_ACVR1_ALK1; Catalytic domain of the Serine/Threonine Kinases, Activin Type I Receptor and Activin receptor-Like Kinase 1
    pfam08515
    Location:174 → 201
    TGF_beta_GS; Transforming growth factor beta type I GS-motif

  2. XM_038577717.1 → XP_038433645.1  serine/threonine-protein kinase receptor R3 isoform X1

    UniProtKB/TrEMBL
    A0A7I8AVG8
    Conserved Domains (2) summary
    cd14142
    Location:216 → 513
    STKc_ACVR1_ALK1; Catalytic domain of the Serine/Threonine Kinases, Activin Type I Receptor and Activin receptor-Like Kinase 1
    pfam08515
    Location:193 → 220
    TGF_beta_GS; Transforming growth factor beta type I GS-motif

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006609.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    43166746..43181176
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014108648.3 → XP_013964123.2  serine/threonine-protein kinase receptor R3 isoform X2

    UniProtKB/TrEMBL
    A0A7I8AUV5, A0A7I8AVG8, A0A8C0JIT4, A0A8P0SR48
    Conserved Domains (2) summary
    cd14142
    Location:197 → 494
    STKc_ACVR1_ALK1; Catalytic domain of the Serine/Threonine Kinases, Activin Type I Receptor and Activin receptor-Like Kinase 1
    pfam08515
    Location:174 → 201
    TGF_beta_GS; Transforming growth factor beta type I GS-motif

  2. XM_022411071.2 → XP_022266779.2  serine/threonine-protein kinase receptor R3 isoform X1

    UniProtKB/TrEMBL
    A0A7I8AVG8
    Conserved Domains (2) summary
    cd14142
    Location:216 → 513
    STKc_ACVR1_ALK1; Catalytic domain of the Serine/Threonine Kinases, Activin Type I Receptor and Activin receptor-Like Kinase 1
    pfam08515
    Location:193 → 220
    TGF_beta_GS; Transforming growth factor beta type I GS-motif
Nucleotide Protein
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