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PLEKHG6 pleckstrin homology and RhoGEF domain containing G6 [ Canis lupus familiaris (dog) ]

Gene ID: 477717, updated on 5-Mar-2024

Summary

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Official Symbol
PLEKHG6provided by VGNC
Official Full Name
pleckstrin homology and RhoGEF domain containing G6provided by VGNC
Primary source
VGNC:VGNC:44681
See related
Ensembl:ENSCAFG00845029568
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 27
Exon count:
17
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 27 NC_051831.1 (39011002..39026871, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 27 NC_006609.4 (7943742..7959595)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 27 NC_049248.1 (7422587..7438302)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 27 NC_049287.1 (38883535..38899388, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 27 NC_049768.1 (38925020..38940874, complement)

Chromosome 27 - NC_051831.1Genomic Context describing neighboring genes Neighboring gene sodium channel epithelial 1 subunit alpha Neighboring gene TNF receptor superfamily member 1A Neighboring gene uncharacterized LOC119866330 Neighboring gene uncharacterized LOC111092895 Neighboring gene CD9 molecule

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: pleckstrin homology domain-containing family G member 6; pleckstrin homology domain-containing family G member 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051831.1 Reference ROS_Cfam_1.0

    Range
    39011002..39026871 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038439223.1 → XP_038295151.1  pleckstrin homology domain-containing family G member 6

    UniProtKB/TrEMBL
    A0A8C0PE05, A0A8I3Q1U7
    Conserved Domains (2) summary
    cd13244
    Location:408 → 506
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    pfam00621
    Location:165 → 351
    RhoGEF; RhoGEF domain

  2. XM_038439221.1 → XP_038295149.1  pleckstrin homology domain-containing family G member 6

    UniProtKB/TrEMBL
    A0A8C0PE05, A0A8I3Q1U7
    Conserved Domains (2) summary
    cd13244
    Location:408 → 506
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    pfam00621
    Location:165 → 351
    RhoGEF; RhoGEF domain

  3. XM_038439222.1 → XP_038295150.1  pleckstrin homology domain-containing family G member 6

    UniProtKB/TrEMBL
    A0A8C0PE05, A0A8I3Q1U7
    Related
    ENSCAFP00845041078.1, ENSCAFT00845052365.1
    Conserved Domains (2) summary
    cd13244
    Location:408 → 506
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    pfam00621
    Location:165 → 351
    RhoGEF; RhoGEF domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049287.1 Alternate UMICH_Zoey_3.1

    Range
    38883535..38899388 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038513886.1 → XP_038369814.1  pleckstrin homology domain-containing family G member 6

    Conserved Domains (2) summary
    cd13244
    Location:408 → 506
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    pfam00621
    Location:165 → 351
    RhoGEF; RhoGEF domain

  2. XM_038513884.1 → XP_038369812.1  pleckstrin homology domain-containing family G member 6

    Conserved Domains (2) summary
    cd13244
    Location:408 → 506
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    pfam00621
    Location:165 → 351
    RhoGEF; RhoGEF domain

  3. XM_038513885.1 → XP_038369813.1  pleckstrin homology domain-containing family G member 6

    Conserved Domains (2) summary
    cd13244
    Location:408 → 506
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    pfam00621
    Location:165 → 351
    RhoGEF; RhoGEF domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049768.1 Alternate UNSW_CanFamBas_1.0

    Range
    38925020..38940874 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038641730.1 → XP_038497658.1  pleckstrin homology domain-containing family G member 6

  2. XM_038641728.1 → XP_038497656.1  pleckstrin homology domain-containing family G member 6

  3. XM_038641729.1 → XP_038497657.1  pleckstrin homology domain-containing family G member 6

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049248.1 Alternate UU_Cfam_GSD_1.0

    Range
    7422587..7438302
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038576556.1 → XP_038432484.1  LOW QUALITY PROTEIN: pleckstrin homology domain-containing family G member 6

    UniProtKB/TrEMBL
    A0A8C0PE05, A0A8I3Q1U7
    Conserved Domains (2) summary
    cd13244
    Location:408 → 506
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    pfam00621
    Location:165 → 351
    RhoGEF; RhoGEF domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006609.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    7943742..7959595
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038459734.1 → XP_038315662.1  pleckstrin homology domain-containing family G member 6

    UniProtKB/TrEMBL
    A0A8C0PE05, A0A8C0TC04, A0A8P0NMZ4
    Conserved Domains (2) summary
    cd13244
    Location:408 → 506
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    pfam00621
    Location:165 → 351
    RhoGEF; RhoGEF domain

  2. XM_038459736.1 → XP_038315664.1  pleckstrin homology domain-containing family G member 6

    UniProtKB/TrEMBL
    A0A8C0PE05, A0A8C0TC04, A0A8P0NMZ4
    Conserved Domains (2) summary
    cd13244
    Location:408 → 506
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    pfam00621
    Location:165 → 351
    RhoGEF; RhoGEF domain

  3. XM_534913.6 → XP_534913.2  pleckstrin homology domain-containing family G member 6

    UniProtKB/TrEMBL
    A0A8C0PE05, A0A8C0TC04, A0A8P0NMZ4
    Conserved Domains (2) summary
    cd13244
    Location:408 → 506
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    pfam00621
    Location:165 → 351
    RhoGEF; RhoGEF domain
Nucleotide Protein
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