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SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 [ Canis lupus familiaris (dog) ]

Gene ID: 479598, updated on 5-Mar-2024

Summary

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Official Symbol
SPSB1provided by VGNC
Official Full Name
splA/ryanodine receptor domain and SOCS box containing 1provided by VGNC
Primary source
VGNC:VGNC:46770
See related
Ensembl:ENSCAFG00845028867
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (62825418..62894575)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (62616269..62685333)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (63091729..63160856)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (62824606..62892430)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (62687237..62756451)

Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene serine/arginine repetitive matrix protein 1-like Neighboring gene uncharacterized LOC111095990 Neighboring gene hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Neighboring gene uncharacterized LOC119871912 Neighboring gene uncharacterized LOC111095991

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
SPRY domain-containing SOCS box protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051809.1 Reference ROS_Cfam_1.0

    Range
    62825418..62894575
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038666649.1 → XP_038522577.1  SPRY domain-containing SOCS box protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SIU3, A0A8I3PZR9
    Related
    ENSCAFP00845039979.1, ENSCAFT00845050999.1
    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

  2. XM_038666648.1 → XP_038522576.1  SPRY domain-containing SOCS box protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SIU3, A0A8I3PZR9
    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

  3. XM_038666646.1 → XP_038522574.1  SPRY domain-containing SOCS box protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SIU3, A0A8I3PZR9
    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

  4. XM_038666647.1 → XP_038522575.1  SPRY domain-containing SOCS box protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SIU3, A0A8I3PZR9
    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

  5. XM_038666644.1 → XP_038522572.1  SPRY domain-containing SOCS box protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3Q1V6, A0A8I3Q1W3, A0A8P0SNW7, A0A8P0TB48
    Related
    ENSCAFP00845040006.1, ENSCAFT00845051030.1
    Conserved Domains (2) summary
    cd12906
    Location:128 → 301
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)
    cl02533
    Location:306 → 347
    SOCS; SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins ...

  6. XM_038666645.1 → XP_038522573.1  SPRY domain-containing SOCS box protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SIU3, A0A8I3PZR9
    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049265.1 Alternate UMICH_Zoey_3.1

    Range
    62824606..62892430
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038476748.1 → XP_038332676.1  SPRY domain-containing SOCS box protein 1 isoform X2

    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

  2. XM_038476746.1 → XP_038332674.1  SPRY domain-containing SOCS box protein 1 isoform X2

    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

  3. XM_038476747.1 → XP_038332675.1  SPRY domain-containing SOCS box protein 1 isoform X2

    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

  4. XM_038476744.1 → XP_038332672.1  SPRY domain-containing SOCS box protein 1 isoform X1

    Conserved Domains (2) summary
    cd12906
    Location:128 → 301
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)
    cl02533
    Location:306 → 347
    SOCS; SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins ...

  5. XM_038476745.1 → XP_038332673.1  SPRY domain-containing SOCS box protein 1 isoform X2

    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

    Range
    62687237..62756451
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038602042.1 → XP_038457970.1  SPRY domain-containing SOCS box protein 1 isoform X2

    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

  2. XM_038602041.1 → XP_038457969.1  SPRY domain-containing SOCS box protein 1 isoform X2

    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

  3. XM_038602039.1 → XP_038457967.1  SPRY domain-containing SOCS box protein 1 isoform X2

    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

  4. XM_038602040.1 → XP_038457968.1  SPRY domain-containing SOCS box protein 1 isoform X2

    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

  5. XM_038602037.1 → XP_038457965.1  SPRY domain-containing SOCS box protein 1 isoform X1

    Conserved Domains (2) summary
    cd12906
    Location:128 → 301
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)
    cl02533
    Location:306 → 347
    SOCS; SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins ...

  6. XM_038602038.1 → XP_038457966.1  SPRY domain-containing SOCS box protein 1 isoform X2

    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

    Range
    63091729..63160856
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038537905.1 → XP_038393833.1  SPRY domain-containing SOCS box protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SIU3, A0A8I3PZR9
    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

  2. XM_038537903.1 → XP_038393831.1  SPRY domain-containing SOCS box protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SIU3, A0A8I3PZR9
    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

  3. XM_038537901.1 → XP_038393829.1  SPRY domain-containing SOCS box protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SIU3, A0A8I3PZR9
    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

  4. XM_038537902.1 → XP_038393830.1  SPRY domain-containing SOCS box protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SIU3, A0A8I3PZR9
    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

  5. XM_038537899.1 → XP_038393827.1  SPRY domain-containing SOCS box protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3Q1V6, A0A8I3Q1W3, A0A8P0SNW7, A0A8P0TB48
    Conserved Domains (2) summary
    cd12906
    Location:128 → 301
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)
    cl02533
    Location:306 → 347
    SOCS; SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins ...

  6. XM_038537900.1 → XP_038393828.1  SPRY domain-containing SOCS box protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SIU3, A0A8I3PZR9
    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    62616269..62685333
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038524473.1 → XP_038380401.1  SPRY domain-containing SOCS box protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SIU3, A0A8I3PZR9
    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

  2. XM_038524463.1 → XP_038380391.1  SPRY domain-containing SOCS box protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SIU3, A0A8I3PZR9
    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

  3. XM_038524447.1 → XP_038380375.1  SPRY domain-containing SOCS box protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SIU3, A0A8I3PZR9
    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

  4. XM_038524456.1 → XP_038380384.1  SPRY domain-containing SOCS box protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SIU3, A0A8I3PZR9
    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

  5. XM_038524426.1 → XP_038380354.1  SPRY domain-containing SOCS box protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3Q1V6, A0A8I3Q1W3, A0A8P0SNW7, A0A8P0TB48
    Conserved Domains (2) summary
    cd12906
    Location:128 → 301
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)
    cl02533
    Location:306 → 347
    SOCS; SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins ...

  6. XM_038524436.1 → XP_038380364.1  SPRY domain-containing SOCS box protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SIU3, A0A8I3PZR9
    Conserved Domains (2) summary
    cd03744
    Location:232 → 273
    SOCS_SSB1; SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
    cd12906
    Location:54 → 227
    SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)
Nucleotide Protein
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