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LGMN legumain [ Canis lupus familiaris (dog) ]

Gene ID: 480232, updated on 5-Mar-2024

Summary

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Official Symbol
LGMNprovided by VGNC
Official Full Name
legumainprovided by VGNC
Primary source
VGNC:VGNC:42654
See related
Ensembl:ENSCAFG00845021275
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (1864425..1878822, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (1834051..1866767, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (1879451..1912213, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (1802050..1834797, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (1752395..1785146, complement)

Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene Ras and Rab interactor 3 Neighboring gene 60S ribosomal protein L21-like Neighboring gene uncharacterized LOC119872806 Neighboring gene uncharacterized LOC119872807 Neighboring gene golgin A5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis involved in protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in vacuolar protein processing IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
legumain
XP_022277491.1
XP_038338633.1
XP_038338634.1
XP_038400053.1
XP_038400054.1
XP_038464176.1
XP_038464177.1
XP_038528856.1
XP_537355.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051812.1 Reference ROS_Cfam_1.0

    Range
    1864425..1878822 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038672928.1 → XP_038528856.1  legumain isoform X1

    UniProtKB/TrEMBL
    A0A8I3PI32
    Related
    ENSCAFP00845030175.1, ENSCAFT00845038539.1
    Conserved Domains (2) summary
    pfam01650
    Location:50 → 283
    Peptidase_C13; Peptidase C13 family
    cd21115
    Location:307 → 427
    legumain_C; C-terminal prodomain of legumain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049268.1 Alternate UMICH_Zoey_3.1

    Range
    1802050..1834797 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038482705.1 → XP_038338633.1  legumain isoform X2

  2. XM_038482706.1 → XP_038338634.1  legumain isoform X3

    Conserved Domains (2) summary
    pfam01650
    Location:19 → 257
    Peptidase_C13; Peptidase C13 family
    cd21115
    Location:281 → 401
    legumain_C; C-terminal prodomain of legumain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

    Range
    1752395..1785146 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038608248.1 → XP_038464176.1  legumain isoform X4

  2. XM_038608249.1 → XP_038464177.1  legumain isoform X5

    Conserved Domains (2) summary
    pfam01650
    Location:19 → 257
    Peptidase_C13; Peptidase C13 family
    cd21115
    Location:281 → 401
    legumain_C; C-terminal prodomain of legumain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

    Range
    1879451..1912213 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038544125.1 → XP_038400053.1  legumain isoform X6

    UniProtKB/TrEMBL
    A0A8C0L7A0, A0A8C0LXP0, A0A8C0T170, A0A8P0ND98

  2. XM_038544126.1 → XP_038400054.1  legumain isoform X7

    UniProtKB/TrEMBL
    A0A8C0SYG9, A0A8I3PI32, A0A8P0T5J3
    Conserved Domains (2) summary
    pfam01650
    Location:19 → 257
    Peptidase_C13; Peptidase C13 family
    cd21115
    Location:281 → 401
    legumain_C; C-terminal prodomain of legumain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    1834051..1866767 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_537355.7 → XP_537355.2  legumain isoform X8

    UniProtKB/TrEMBL
    A0A8C0L7A0, A0A8C0LXP0, A0A8C0T170, A0A8P0ND98
    Conserved Domains (1) summary
    pfam01650
    Location:29 → 285
    Peptidase_C13; Peptidase C13 family

  2. XM_022421783.2 → XP_022277491.1  legumain isoform X9

    UniProtKB/TrEMBL
    A0A8C0SYG9, A0A8I3PI32, A0A8P0T5J3
    Conserved Domains (2) summary
    pfam01650
    Location:19 → 257
    Peptidase_C13; Peptidase C13 family
    cd21115
    Location:281 → 401
    legumain_C; C-terminal prodomain of legumain
Nucleotide Protein
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