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DLA-DRA MHC class II DR alpha chain [ Canis lupus familiaris (dog) ]

Gene ID: 481731, updated on 17-Aug-2022

Summary

Gene symbol
DLA-DRA
Gene description
MHC class II DR alpha chain
See related
Ensembl:ENSCAFG00845017467
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
DLA-DRA1
Orthologs
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Genomic context

See DLA-DRA in Genome Data Viewer
Location:
chromosome: 12
Exon count:
5
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (2409388..2414180)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (2282352..2285906)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (2287866..2291417)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (2132677..2136225)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (2213826..2217378)
105 previous assembly CanFam3.1 (GCF_000002285.3) 12 NC_006594.3 (2133026..2137825)

Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene peptidyl-prolyl cis-trans isomerase FKBP1A-like Neighboring gene butyrophilin like 2 Neighboring gene ATP synthase subunit g, mitochondrial-like Neighboring gene uncharacterized LOC119874143 Neighboring gene 60S ribosomal protein L7a-like Neighboring gene MHC class II DLA DRB1 beta chain Neighboring gene major histocompatibility complex, class II, DQ alpha 1

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Homology

General protein information

Preferred Names
MHC class II DR alpha chain

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001011723.1NP_001011723.1  MHC class II DR alpha chain precursor

    See identical proteins and their annotated locations for NP_001011723.1

    Status: PROVISIONAL

    Source sequence(s)
    L37332
    UniProtKB/TrEMBL
    A0A8C0JK13, A0A8C0RKX0, F1PLW1, Q30437
    Conserved Domains (3) summary
    pfam00993
    Location:29108
    MHC_II_alpha; Class II histocompatibility antigen, alpha domain
    cd00096
    Location:111119
    Ig; Ig strand A [structural motif]
    cl11960
    Location:110204
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051816.1 Reference ROS_Cfam_1.0

    Range
    2409388..2414180
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038682742.1XP_038538670.1  MHC class II DR alpha chain isoform X1

    UniProtKB/TrEMBL
    A0A8C0JK13, A0A8C0RKX0, F1PLW1
    Related
    ENSCAFP00845024273.1, ENSCAFT00845030976.1
    Conserved Domains (3) summary
    pfam00993
    Location:29108
    MHC_II_alpha; Class II histocompatibility antigen, alpha domain
    cd00096
    Location:111119
    Ig; Ig strand A [structural motif]
    cl11960
    Location:110204
    Ig; Immunoglobulin domain
  2. XM_038682741.1XP_038538669.1  MHC class II DR alpha chain isoform X1

    UniProtKB/TrEMBL
    A0A8C0JK13, A0A8C0RKX0, F1PLW1
    Related
    ENSCAFP00845024244.1, ENSCAFT00845030935.1
    Conserved Domains (3) summary
    pfam00993
    Location:29108
    MHC_II_alpha; Class II histocompatibility antigen, alpha domain
    cd00096
    Location:111119
    Ig; Ig strand A [structural motif]
    cl11960
    Location:110204
    Ig; Immunoglobulin domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049272.1 Alternate UMICH_Zoey_3.1

    Range
    2132677..2136225
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

    Range
    2213826..2217378
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

    Range
    2287866..2291417
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    2282352..2285906
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)