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PTGDR2 prostaglandin D2 receptor 2 [ Canis lupus familiaris (dog) ]

Gene ID: 483805, updated on 5-Mar-2024

Summary

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Official Symbol
PTGDR2provided by VGNC
Official Full Name
prostaglandin D2 receptor 2provided by VGNC
Primary source
VGNC:VGNC:45141
See related
Ensembl:ENSCAFG00845018195
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
CRTH2; GPR44
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 18
Exon count:
3
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 18 NC_051822.1 (56474768..56479958)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 18 NC_006600.4 (54002288..54003490)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 18 NC_049239.1 (56037704..56038906)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 18 NC_049278.1 (55534988..55536190)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 18 NC_049759.1 (55156526..55157727)

Chromosome 18 - NC_051822.1Genomic Context describing neighboring genes Neighboring gene zona pellucida glycoprotein 1 Neighboring gene uncharacterized LOC119864287 Neighboring gene uncharacterized LOC119864286 Neighboring gene coiled-coil domain containing 86 Neighboring gene membrane spanning 4-domains A15

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables complement receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement receptor mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cytosolic calcium ion concentration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
prostaglandin D2 receptor 2
Names
G protein-coupled receptor 44
G-protein coupled receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001048107.1 → NP_001041572.1  prostaglandin D2 receptor 2

    See identical proteins and their annotated locations for NP_001041572.1

    Status: PROVISIONAL

    Source sequence(s)
    AM231750
    UniProtKB/TrEMBL
    A0A8C0KJZ6, A0A8C0QB37, Q2A652
    Related
    ENSCAFP00845025302.1, ENSCAFT00845032371.1
    Conserved Domains (2) summary
    cd14964
    Location:35 → 59
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:33 → 315
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051822.1 Reference ROS_Cfam_1.0

    Range
    56474768..56479958
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038423474.1 → XP_038279402.1  prostaglandin D2 receptor 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0NYW6, A0A8I3P5Y8
    Conserved Domains (2) summary
    cd14964
    Location:34 → 60
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:33 → 315
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049278.1 Alternate UMICH_Zoey_3.1

    Range
    55534988..55536190
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049759.1 Alternate UNSW_CanFamBas_1.0

    Range
    55156526..55157727
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049239.1 Alternate UU_Cfam_GSD_1.0

    Range
    56037704..56038906
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006600.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    54002288..54003490
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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