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CNOT3 CCR4-NOT transcription complex subunit 3 [ Homo sapiens (human) ]

Gene ID: 4849, updated on 3-Apr-2024

Summary

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Official Symbol
CNOT3provided by HGNC
Official Full Name
CCR4-NOT transcription complex subunit 3provided by HGNC
Primary source
HGNC:HGNC:7879
See related
Ensembl:ENSG00000088038 MIM:604910; AllianceGenome:HGNC:7879
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NOT3; LENG2; NOT3H; IDDSADF
Summary
Involved in regulation of stem cell population maintenance. Part of CCR4-NOT complex. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis (RPKM 13.9), spleen (RPKM 9.7) and 25 other tissues See more
Orthologs
mouse all
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Genomic context

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Location:
19q13.42
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (54137762..54155681)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (57217961..57235947)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (54641478..54659419)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene NADH:ubiquinone oxidoreductase subunit A3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:54617323-54618196 Neighboring gene TCF3 fusion partner Neighboring gene PRPF31 antisense RNA 1 Neighboring gene pre-mRNA processing factor 31 Neighboring gene uncharacterized LOC102724273 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:54662792-54663461 Neighboring gene leukocyte receptor cluster member 1 Neighboring gene transmembrane channel like 4 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:54676977-54677793 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:54677794-54678609 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:54683683-54684198 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:54684199-54684714 Neighboring gene membrane bound O-acyltransferase domain containing 7 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:54684715-54685229 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:54687509-54688008 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:54692762-54693444 Neighboring gene tRNA splicing endonuclease subunit 34

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Clinical features of CNOT3-associated neurodevelopmental disorder in three Chinese patients. Zhao P, et al. Neurogenetics, 2023 Apr. PMID 36802310
  2. Inherited cases of CNOT3-associated intellectual developmental disorder with speech delay, autism, and dysmorphic facies. Meyer R, et al. Clin Genet, 2020 Oct. PMID 32720325
  3. De novo variants in CNOT3 cause a variable neurodevelopmental disorder. Martin R, et al. Eur J Hum Genet, 2019 Nov. PMID 31201375, Free PMC Article
  4. CNOT3 targets negative cell cycle regulators in non-small cell lung cancer development. Shirai YT, et al. Oncogene, 2019 Apr. PMID 30531840
  5. Cnot3 enhances human embryonic cardiomyocyte proliferation by promoting cell cycle inhibitor mRNA degradation. Zhou B, et al. Sci Rep, 2017 May 4. PMID 28473716, Free PMC Article

See all (97) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Translation efficiency driven by CNOT3 subunit of the CCR4-NOT complex promotes leukemogenesis.
    Title: Translation efficiency driven by CNOT3 subunit of the CCR4-NOT complex promotes leukemogenesis.
  2. CCR4-NOT differentially controls host versus virus poly(a)-tail length and regulates HCMV infection.
    Title: CCR4-NOT differentially controls host versus virus poly(a)-tail length and regulates HCMV infection.
  3. Clinical features of CNOT3-associated neurodevelopmental disorder in three Chinese patients.
    Title: Clinical features of CNOT3-associated neurodevelopmental disorder in three Chinese patients.
  4. CNOT3 interacts with the Aurora B and MAPK/ERK kinases to promote survival of differentiating mesendodermal progenitor cells.
    Title: CNOT3 interacts with the Aurora B and MAPK/ERK kinases to promote survival of differentiating mesendodermal progenitor cells.
  5. Determinants of Disease Penetrance in PRPF31-Associated Retinopathy.
    Title: Determinants of Disease Penetrance in PRPF31-Associated Retinopathy.
  6. A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with NTNG1 and CNOT3.
    Title: A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with NTNG1 and CNOT3.
  7. Inherited cases of CNOT3-associated intellectual developmental disorder with speech delay, autism, and dysmorphic facies.
    Title: Inherited cases of CNOT3-associated intellectual developmental disorder with speech delay, autism, and dysmorphic facies.
  8. The pleiotropy associated with de novo variants in CHD4, CNOT3, and SETD5 extends to moyamoya angiopathy.
    Title: The pleiotropy associated with de novo variants in CHD4, CNOT3, and SETD5 extends to moyamoya angiopathy.
  9. De novo variants in CNOT3 cause a variable neurodevelopmental disorder.
    Title: De novo variants in CNOT3 cause a variable neurodevelopmental disorder.
  10. CCR4-NOT transcription complex subunit 3 (CNOT3) is up-regulated in lung cancer tissues and is associated with poor prognosis of the patients. Knocking down CNOT3 expression sensitizes cisplatin-resistant A549 (A549/DDP) cells to cisplatin-induced apoptosis. CNOT3 depletion up-regulates the expression level of RIPK3 and the enhanced apoptosis is mediated by the elevated RIPK3 to further trigger Caspase 8 activation.
    Title: CNOT3 contributes to cisplatin resistance in lung cancer through inhibiting RIPK3 expression.
Submit: New GeneRIF Correction See all GeneRIFs (23)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Intellectual developmental disorder with speech delay, autism, and dysmorphic facies
MedGen: C5231456 OMIM: 618672 GeneReviews: Not available
Compare labs

Copy number response

Description
Copy number response
Haploinsufficency

No evidence available (Last evaluated 2018-06-27)

ClinGen Genome Curation Page
Triplosensitivity

No evidence available (Last evaluated 2018-06-27)

ClinGen Genome Curation Page

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • KIAA0691

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in nuclear-transcribed mRNA poly(A) tail shortening IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in nuclear-transcribed mRNA poly(A) tail shortening NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in positive regulation of cold-induced thermogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of stem cell population maintenance IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of stem cell population maintenance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of translation IEA
Inferred from Electronic Annotation
more info
  
involved_in regulatory ncRNA-mediated gene silencing IEA
Inferred from Electronic Annotation
more info
  
involved_in trophectodermal cell differentiation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of CCR4-NOT complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of CCR4-NOT complex NAS
Non-traceable Author Statement
more info
 PubMed 
part_of CCR4-NOT core complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in P-body IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in P-body ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytosol TAS
Traceable Author Statement
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
CCR4-NOT transcription complex subunit 3
Names
CCR4-associated factor 3
NOT3 (negative regulator of transcription 3, yeast) homolog
leukocyte receptor cluster member 2

NCBI Reference Sequences (RefSeq)

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NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014516.4 → NP_055331.1  CCR4-NOT transcription complex subunit 3

    See identical proteins and their annotated locations for NP_055331.1

    Status: VALIDATED

    Source sequence(s)
    AC245052
    Consensus CDS
    CCDS12880.1
    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76
    UniProtKB/TrEMBL
    B7Z6J7
    Related
    ENSP00000221232.5, ENST00000221232.11
    Conserved Domains (2) summary
    COG5665
    Location:12 → 751
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    pfam04065
    Location:3 → 229
    Not3; Not1 N-terminal domain, CCR4-Not complex component

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    54137762..54155681
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047438877.1 → XP_047294833.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  2. XM_047438878.1 → XP_047294834.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  3. XM_047438866.1 → XP_047294822.1  CCR4-NOT transcription complex subunit 3 isoform X1

  4. XM_047438874.1 → XP_047294830.1  CCR4-NOT transcription complex subunit 3 isoform X5

  5. XM_047438879.1 → XP_047294835.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  6. XM_005278280.3 → XP_005278337.1  CCR4-NOT transcription complex subunit 3 isoform X1

    See identical proteins and their annotated locations for XP_005278337.1

    UniProtKB/TrEMBL
    B7Z6J7
    Conserved Domains (2) summary
    COG5665
    Location:12 → 769
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    pfam04065
    Location:3 → 230
    Not3; Not1 N-terminal domain, CCR4-Not complex component

  7. XM_047438872.1 → XP_047294828.1  CCR4-NOT transcription complex subunit 3 isoform X5

  8. XM_047438867.1 → XP_047294823.1  CCR4-NOT transcription complex subunit 3 isoform X2

  9. XM_047438875.1 → XP_047294831.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76
    Related
    ENSP00000351159.4, ENST00000358389.7

  10. XM_005278279.3 → XP_005278336.1  CCR4-NOT transcription complex subunit 3 isoform X1

    See identical proteins and their annotated locations for XP_005278336.1

    UniProtKB/TrEMBL
    B7Z6J7
    Conserved Domains (2) summary
    COG5665
    Location:12 → 769
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    pfam04065
    Location:3 → 230
    Not3; Not1 N-terminal domain, CCR4-Not complex component

  11. XM_005278282.4 → XP_005278339.1  CCR4-NOT transcription complex subunit 3 isoform X5

    See identical proteins and their annotated locations for XP_005278339.1

    UniProtKB/TrEMBL
    B7Z6J7
    Conserved Domains (2) summary
    COG5665
    Location:12 → 752
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    pfam04065
    Location:3 → 230
    Not3; Not1 N-terminal domain, CCR4-Not complex component

  12. XM_005278281.3 → XP_005278338.1  CCR4-NOT transcription complex subunit 3 isoform X2

    See identical proteins and their annotated locations for XP_005278338.1

    UniProtKB/TrEMBL
    B7Z6J7
    Conserved Domains (2) summary
    COG5665
    Location:12 → 768
    COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
    pfam04065
    Location:3 → 229
    Not3; Not1 N-terminal domain, CCR4-Not complex component

  13. XM_047438869.1 → XP_047294825.1  CCR4-NOT transcription complex subunit 3 isoform X3

  14. XM_047438871.1 → XP_047294827.1  CCR4-NOT transcription complex subunit 3 isoform X4

  15. XM_047438880.1 → XP_047294836.1  CCR4-NOT transcription complex subunit 3 isoform X8

    Related
    ENSP00000496602.1, ENST00000617930.2

  16. XM_047438870.1 → XP_047294826.1  CCR4-NOT transcription complex subunit 3 isoform X4

  17. XM_011526993.4 → XP_011525295.1  CCR4-NOT transcription complex subunit 3 isoform X7

    See identical proteins and their annotated locations for XP_011525295.1

    UniProtKB/TrEMBL
    B7Z6J7
    Conserved Domains (2) summary
    pfam04065
    Location:3 → 230
    Not3; Not1 N-terminal domain, CCR4-Not complex component
    cl02384
    Location:625 → 678
    NOT2_3_5; NOT2 / NOT3 / NOT5 family

  18. XM_047438868.1 → XP_047294824.1  CCR4-NOT transcription complex subunit 3 isoform X2

  19. XM_047438873.1 → XP_047294829.1  CCR4-NOT transcription complex subunit 3 isoform X5

  20. XM_047438876.1 → XP_047294832.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NW_003571054.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    112518..130531
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054329698.1 → XP_054185673.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  2. XM_054329685.1 → XP_054185660.1  CCR4-NOT transcription complex subunit 3 isoform X1

  3. XM_054329694.1 → XP_054185669.1  CCR4-NOT transcription complex subunit 3 isoform X5

  4. XM_054329687.1 → XP_054185662.1  CCR4-NOT transcription complex subunit 3 isoform X2

  5. XM_054329695.1 → XP_054185670.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  6. XM_054329684.1 → XP_054185659.1  CCR4-NOT transcription complex subunit 3 isoform X1

  7. XM_054329693.1 → XP_054185668.1  CCR4-NOT transcription complex subunit 3 isoform X5

  8. XM_054329686.1 → XP_054185661.1  CCR4-NOT transcription complex subunit 3 isoform X2

  9. XM_054329690.1 → XP_054185665.1  CCR4-NOT transcription complex subunit 3 isoform X3

  10. XM_054329692.1 → XP_054185667.1  CCR4-NOT transcription complex subunit 3 isoform X4

  11. XM_054329689.1 → XP_054185664.1  CCR4-NOT transcription complex subunit 3 isoform X3

  12. XM_054329691.1 → XP_054185666.1  CCR4-NOT transcription complex subunit 3 isoform X4

  13. XM_054329699.1 → XP_054185674.1  CCR4-NOT transcription complex subunit 3 isoform X7

  14. XM_054329697.1 → XP_054185672.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  15. XM_054329688.1 → XP_054185663.1  CCR4-NOT transcription complex subunit 3 isoform X2

  16. XM_054329696.1 → XP_054185671.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

Reference GRCh38.p14 ALT_REF_LOCI_2

Genomic

  1. NW_003571055.2 Reference GRCh38.p14 ALT_REF_LOCI_2

    Range
    112518..130532
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054330191.1 → XP_054186166.1  CCR4-NOT transcription complex subunit 3 isoform X5

  2. XM_054330195.1 → XP_054186170.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  3. XM_054330181.1 → XP_054186156.1  CCR4-NOT transcription complex subunit 3 isoform X1

  4. XM_054330180.1 → XP_054186155.1  CCR4-NOT transcription complex subunit 3 isoform X1

  5. XM_054330189.1 → XP_054186164.1  CCR4-NOT transcription complex subunit 3 isoform X5

  6. XM_054330183.1 → XP_054186158.1  CCR4-NOT transcription complex subunit 3 isoform X2

  7. XM_054330192.1 → XP_054186167.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  8. XM_054330179.1 → XP_054186154.1  CCR4-NOT transcription complex subunit 3 isoform X1

  9. XM_054330188.1 → XP_054186163.1  CCR4-NOT transcription complex subunit 3 isoform X5

  10. XM_054330182.1 → XP_054186157.1  CCR4-NOT transcription complex subunit 3 isoform X2

  11. XM_054330198.1 → XP_054186173.1  CCR4-NOT transcription complex subunit 3 isoform X8

  12. XM_054330187.1 → XP_054186162.1  CCR4-NOT transcription complex subunit 3 isoform X4

  13. XM_054330185.1 → XP_054186160.1  CCR4-NOT transcription complex subunit 3 isoform X3

  14. XM_054330197.1 → XP_054186172.1  CCR4-NOT transcription complex subunit 3 isoform X8

  15. XM_054330186.1 → XP_054186161.1  CCR4-NOT transcription complex subunit 3 isoform X4

  16. XM_054330196.1 → XP_054186171.1  CCR4-NOT transcription complex subunit 3 isoform X7

  17. XM_054330184.1 → XP_054186159.1  CCR4-NOT transcription complex subunit 3 isoform X2

  18. XM_054330190.1 → XP_054186165.1  CCR4-NOT transcription complex subunit 3 isoform X5

  19. XM_054330193.1 → XP_054186168.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  20. XM_054330194.1 → XP_054186169.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

Reference GRCh38.p14 ALT_REF_LOCI_3

Genomic

  1. NW_003571056.2 Reference GRCh38.p14 ALT_REF_LOCI_3

    Range
    112518..130532
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054330492.1 → XP_054186467.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  2. XM_054330478.1 → XP_054186453.1  CCR4-NOT transcription complex subunit 3 isoform X1

  3. XM_054330477.1 → XP_054186452.1  CCR4-NOT transcription complex subunit 3 isoform X1

  4. XM_054330487.1 → XP_054186462.1  CCR4-NOT transcription complex subunit 3 isoform X5

  5. XM_054330480.1 → XP_054186455.1  CCR4-NOT transcription complex subunit 3 isoform X2

  6. XM_054330490.1 → XP_054186465.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  7. XM_054330476.1 → XP_054186451.1  CCR4-NOT transcription complex subunit 3 isoform X1

  8. XM_054330486.1 → XP_054186461.1  CCR4-NOT transcription complex subunit 3 isoform X5

  9. XM_054330479.1 → XP_054186454.1  CCR4-NOT transcription complex subunit 3 isoform X2

  10. XM_054330496.1 → XP_054186471.1  CCR4-NOT transcription complex subunit 3 isoform X8

  11. XM_054330485.1 → XP_054186460.1  CCR4-NOT transcription complex subunit 3 isoform X4

  12. XM_054330483.1 → XP_054186458.1  CCR4-NOT transcription complex subunit 3 isoform X3

  13. XM_054330495.1 → XP_054186470.1  CCR4-NOT transcription complex subunit 3 isoform X8

  14. XM_054330484.1 → XP_054186459.1  CCR4-NOT transcription complex subunit 3 isoform X4

  15. XM_054330494.1 → XP_054186469.1  CCR4-NOT transcription complex subunit 3 isoform X7

  16. XM_054330481.1 → XP_054186456.1  CCR4-NOT transcription complex subunit 3 isoform X2

  17. XM_054330488.1 → XP_054186463.1  CCR4-NOT transcription complex subunit 3 isoform X5

  18. XM_054330491.1 → XP_054186466.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  19. XM_054330482.1 → XP_054186457.1  CCR4-NOT transcription complex subunit 3 isoform X2

  20. XM_054330489.1 → XP_054186464.1  CCR4-NOT transcription complex subunit 3 isoform X5

  21. XM_054330493.1 → XP_054186468.1  CCR4-NOT transcription complex subunit 3 isoform X9

Reference GRCh38.p14 ALT_REF_LOCI_4

Genomic

  1. NW_003571057.2 Reference GRCh38.p14 ALT_REF_LOCI_4

    Range
    112518..130532
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054330739.1 → XP_054186714.1  CCR4-NOT transcription complex subunit 3 isoform X5

  2. XM_054330743.1 → XP_054186718.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  3. XM_054330729.1 → XP_054186704.1  CCR4-NOT transcription complex subunit 3 isoform X1

  4. XM_054330737.1 → XP_054186712.1  CCR4-NOT transcription complex subunit 3 isoform X5

  5. XM_054330731.1 → XP_054186706.1  CCR4-NOT transcription complex subunit 3 isoform X2

  6. XM_054330740.1 → XP_054186715.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  7. XM_054330728.1 → XP_054186703.1  CCR4-NOT transcription complex subunit 3 isoform X1

  8. XM_054330736.1 → XP_054186711.1  CCR4-NOT transcription complex subunit 3 isoform X5

  9. XM_054330730.1 → XP_054186705.1  CCR4-NOT transcription complex subunit 3 isoform X2

  10. XM_054330745.1 → XP_054186720.1  CCR4-NOT transcription complex subunit 3 isoform X8

  11. XM_054330734.1 → XP_054186709.1  CCR4-NOT transcription complex subunit 3 isoform X3

  12. XM_054330735.1 → XP_054186710.1  CCR4-NOT transcription complex subunit 3 isoform X4

  13. XM_054330744.1 → XP_054186719.1  CCR4-NOT transcription complex subunit 3 isoform X7

  14. XM_054330732.1 → XP_054186707.1  CCR4-NOT transcription complex subunit 3 isoform X2

  15. XM_054330738.1 → XP_054186713.1  CCR4-NOT transcription complex subunit 3 isoform X5

  16. XM_054330742.1 → XP_054186717.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  17. XM_054330733.1 → XP_054186708.1  CCR4-NOT transcription complex subunit 3 isoform X2

  18. XM_054330741.1 → XP_054186716.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

Reference GRCh38.p14 ALT_REF_LOCI_5

Genomic

  1. NW_003571058.2 Reference GRCh38.p14 ALT_REF_LOCI_5

    Range
    112518..130532
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054330969.1 → XP_054186944.1  CCR4-NOT transcription complex subunit 3 isoform X5

  2. XM_054330971.1 → XP_054186946.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  3. XM_054330960.1 → XP_054186935.1  CCR4-NOT transcription complex subunit 3 isoform X1

  4. XM_054330967.1 → XP_054186942.1  CCR4-NOT transcription complex subunit 3 isoform X5

  5. XM_054330962.1 → XP_054186937.1  CCR4-NOT transcription complex subunit 3 isoform X2

  6. XM_054330970.1 → XP_054186945.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  7. XM_054330959.1 → XP_054186934.1  CCR4-NOT transcription complex subunit 3 isoform X1

  8. XM_054330966.1 → XP_054186941.1  CCR4-NOT transcription complex subunit 3 isoform X5

  9. XM_054330961.1 → XP_054186936.1  CCR4-NOT transcription complex subunit 3 isoform X2

  10. XM_054330976.1 → XP_054186951.1  CCR4-NOT transcription complex subunit 3 isoform X8

  11. XM_054330964.1 → XP_054186939.1  CCR4-NOT transcription complex subunit 3 isoform X3

  12. XM_054330975.1 → XP_054186950.1  CCR4-NOT transcription complex subunit 3 isoform X8

  13. XM_054330965.1 → XP_054186940.1  CCR4-NOT transcription complex subunit 3 isoform X4

  14. XM_054330974.1 → XP_054186949.1  CCR4-NOT transcription complex subunit 3 isoform X7

  15. XM_054330968.1 → XP_054186943.1  CCR4-NOT transcription complex subunit 3 isoform X5

  16. XM_054330973.1 → XP_054186948.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  17. XM_054330963.1 → XP_054186938.1  CCR4-NOT transcription complex subunit 3 isoform X2

  18. XM_054330972.1 → XP_054186947.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

Reference GRCh38.p14 ALT_REF_LOCI_6

Genomic

  1. NW_003571059.2 Reference GRCh38.p14 ALT_REF_LOCI_6

    Range
    112518..130532
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054331252.1 → XP_054187227.1  CCR4-NOT transcription complex subunit 3 isoform X5

  2. XM_054331254.1 → XP_054187229.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  3. XM_054331242.1 → XP_054187217.1  CCR4-NOT transcription complex subunit 3 isoform X1

  4. XM_054331241.1 → XP_054187216.1  CCR4-NOT transcription complex subunit 3 isoform X1

  5. XM_054331251.1 → XP_054187226.1  CCR4-NOT transcription complex subunit 3 isoform X5

  6. XM_054331244.1 → XP_054187219.1  CCR4-NOT transcription complex subunit 3 isoform X2

  7. XM_054331253.1 → XP_054187228.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  8. XM_054331240.1 → XP_054187215.1  CCR4-NOT transcription complex subunit 3 isoform X1

  9. XM_054331250.1 → XP_054187225.1  CCR4-NOT transcription complex subunit 3 isoform X5

  10. XM_054331243.1 → XP_054187218.1  CCR4-NOT transcription complex subunit 3 isoform X2

  11. XM_054331259.1 → XP_054187234.1  CCR4-NOT transcription complex subunit 3 isoform X8

  12. XM_054331249.1 → XP_054187224.1  CCR4-NOT transcription complex subunit 3 isoform X4

  13. XM_054331247.1 → XP_054187222.1  CCR4-NOT transcription complex subunit 3 isoform X3

  14. XM_054331258.1 → XP_054187233.1  CCR4-NOT transcription complex subunit 3 isoform X8

  15. XM_054331248.1 → XP_054187223.1  CCR4-NOT transcription complex subunit 3 isoform X4

  16. XM_054331257.1 → XP_054187232.1  CCR4-NOT transcription complex subunit 3 isoform X7

  17. XM_054331245.1 → XP_054187220.1  CCR4-NOT transcription complex subunit 3 isoform X2

  18. XM_054331255.1 → XP_054187230.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  19. XM_054331246.1 → XP_054187221.1  CCR4-NOT transcription complex subunit 3 isoform X2

  20. XM_054331256.1 → XP_054187231.1  CCR4-NOT transcription complex subunit 3 isoform X10

Reference GRCh38.p14 ALT_REF_LOCI_7

Genomic

  1. NW_003571060.1 Reference GRCh38.p14 ALT_REF_LOCI_7

    Range
    112518..130532
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054331525.1 → XP_054187500.1  CCR4-NOT transcription complex subunit 3 isoform X5

  2. XM_054331528.1 → XP_054187503.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  3. XM_054331517.1 → XP_054187492.1  CCR4-NOT transcription complex subunit 3 isoform X1

  4. XM_054331516.1 → XP_054187491.1  CCR4-NOT transcription complex subunit 3 isoform X1

  5. XM_054331523.1 → XP_054187498.1  CCR4-NOT transcription complex subunit 3 isoform X5

  6. XM_054331519.1 → XP_054187494.1  CCR4-NOT transcription complex subunit 3 isoform X2

  7. XM_054331526.1 → XP_054187501.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  8. XM_054331515.1 → XP_054187490.1  CCR4-NOT transcription complex subunit 3 isoform X1

  9. XM_054331522.1 → XP_054187497.1  CCR4-NOT transcription complex subunit 3 isoform X5

  10. XM_054331518.1 → XP_054187493.1  CCR4-NOT transcription complex subunit 3 isoform X2

  11. XM_054331520.1 → XP_054187495.1  CCR4-NOT transcription complex subunit 3 isoform X3

  12. XM_054331521.1 → XP_054187496.1  CCR4-NOT transcription complex subunit 3 isoform X4

  13. XM_054331529.1 → XP_054187504.1  CCR4-NOT transcription complex subunit 3 isoform X7

  14. XM_054331524.1 → XP_054187499.1  CCR4-NOT transcription complex subunit 3 isoform X5

  15. XM_054331527.1 → XP_054187502.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

Reference GRCh38.p14 ALT_REF_LOCI_8

Genomic

  1. NW_003571061.2 Reference GRCh38.p14 ALT_REF_LOCI_8

    Range
    112518..130532
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333570.1 → XP_054189545.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  2. XM_054333556.1 → XP_054189531.1  CCR4-NOT transcription complex subunit 3 isoform X1

  3. XM_054333565.1 → XP_054189540.1  CCR4-NOT transcription complex subunit 3 isoform X5

  4. XM_054333558.1 → XP_054189533.1  CCR4-NOT transcription complex subunit 3 isoform X2

  5. XM_054333568.1 → XP_054189543.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  6. XM_054333555.1 → XP_054189530.1  CCR4-NOT transcription complex subunit 3 isoform X1

  7. XM_054333564.1 → XP_054189539.1  CCR4-NOT transcription complex subunit 3 isoform X5

  8. XM_054333557.1 → XP_054189532.1  CCR4-NOT transcription complex subunit 3 isoform X2

  9. XM_054333563.1 → XP_054189538.1  CCR4-NOT transcription complex subunit 3 isoform X4

  10. XM_054333561.1 → XP_054189536.1  CCR4-NOT transcription complex subunit 3 isoform X3

  11. XM_054333573.1 → XP_054189548.1  CCR4-NOT transcription complex subunit 3 isoform X8

  12. XM_054333562.1 → XP_054189537.1  CCR4-NOT transcription complex subunit 3 isoform X4

  13. XM_054333572.1 → XP_054189547.1  CCR4-NOT transcription complex subunit 3 isoform X7

  14. XM_054333559.1 → XP_054189534.1  CCR4-NOT transcription complex subunit 3 isoform X2

  15. XM_054333566.1 → XP_054189541.1  CCR4-NOT transcription complex subunit 3 isoform X5

  16. XM_054333571.1 → XP_054189546.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  17. XM_054333560.1 → XP_054189535.1  CCR4-NOT transcription complex subunit 3 isoform X2

  18. XM_054333567.1 → XP_054189542.1  CCR4-NOT transcription complex subunit 3 isoform X5

  19. XM_054333569.1 → XP_054189544.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

Reference GRCh38.p14 ALT_REF_LOCI_9

Genomic

  1. NT_187693.1 Reference GRCh38.p14 ALT_REF_LOCI_9

    Range
    112518..130532
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333668.1 → XP_054189643.1  CCR4-NOT transcription complex subunit 3 isoform X5

  2. XM_054333671.1 → XP_054189646.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  3. XM_054333658.1 → XP_054189633.1  CCR4-NOT transcription complex subunit 3 isoform X1

  4. XM_054333656.1 → XP_054189631.1  CCR4-NOT transcription complex subunit 3 isoform X1

  5. XM_054333666.1 → XP_054189641.1  CCR4-NOT transcription complex subunit 3 isoform X5

  6. XM_054333660.1 → XP_054189635.1  CCR4-NOT transcription complex subunit 3 isoform X2

  7. XM_054333669.1 → XP_054189644.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  8. XM_054333657.1 → XP_054189632.1  CCR4-NOT transcription complex subunit 3 isoform X1

  9. XM_054333665.1 → XP_054189640.1  CCR4-NOT transcription complex subunit 3 isoform X5

  10. XM_054333659.1 → XP_054189634.1  CCR4-NOT transcription complex subunit 3 isoform X2

  11. XM_054333675.1 → XP_054189650.1  CCR4-NOT transcription complex subunit 3 isoform X8

  12. XM_054333664.1 → XP_054189639.1  CCR4-NOT transcription complex subunit 3 isoform X4

  13. XM_054333662.1 → XP_054189637.1  CCR4-NOT transcription complex subunit 3 isoform X3

  14. XM_054333674.1 → XP_054189649.1  CCR4-NOT transcription complex subunit 3 isoform X8

  15. XM_054333663.1 → XP_054189638.1  CCR4-NOT transcription complex subunit 3 isoform X4

  16. XM_054333673.1 → XP_054189648.1  CCR4-NOT transcription complex subunit 3 isoform X7

  17. XM_054333661.1 → XP_054189636.1  CCR4-NOT transcription complex subunit 3 isoform X2

  18. XM_054333667.1 → XP_054189642.1  CCR4-NOT transcription complex subunit 3 isoform X5

  19. XM_054333672.1 → XP_054189647.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  20. XM_054333670.1 → XP_054189645.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    57217961..57235947
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054321095.1 → XP_054177070.1  CCR4-NOT transcription complex subunit 3 isoform X5

  2. XM_054321098.1 → XP_054177073.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  3. XM_054321099.1 → XP_054177074.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  4. XM_054321082.1 → XP_054177057.1  CCR4-NOT transcription complex subunit 3 isoform X1

  5. XM_054321094.1 → XP_054177069.1  CCR4-NOT transcription complex subunit 3 isoform X5

  6. XM_054321100.1 → XP_054177075.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  7. XM_054321081.1 → XP_054177056.1  CCR4-NOT transcription complex subunit 3 isoform X1

  8. XM_054321092.1 → XP_054177067.1  CCR4-NOT transcription complex subunit 3 isoform X5

  9. XM_054321084.1 → XP_054177059.1  CCR4-NOT transcription complex subunit 3 isoform X2

  10. XM_054321096.1 → XP_054177071.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  11. XM_054321080.1 → XP_054177055.1  CCR4-NOT transcription complex subunit 3 isoform X1

  12. XM_054321091.1 → XP_054177066.1  CCR4-NOT transcription complex subunit 3 isoform X5

  13. XM_054321083.1 → XP_054177058.1  CCR4-NOT transcription complex subunit 3 isoform X2

  14. XM_054321088.1 → XP_054177063.1  CCR4-NOT transcription complex subunit 3 isoform X3

  15. XM_054321103.1 → XP_054177078.1  CCR4-NOT transcription complex subunit 3 isoform X8

  16. XM_054321090.1 → XP_054177065.1  CCR4-NOT transcription complex subunit 3 isoform X4

  17. XM_054321087.1 → XP_054177062.1  CCR4-NOT transcription complex subunit 3 isoform X3

  18. XM_054321102.1 → XP_054177077.1  CCR4-NOT transcription complex subunit 3 isoform X8

  19. XM_054321089.1 → XP_054177064.1  CCR4-NOT transcription complex subunit 3 isoform X4

  20. XM_054321101.1 → XP_054177076.1  CCR4-NOT transcription complex subunit 3 isoform X7

  21. XM_054321085.1 → XP_054177060.1  CCR4-NOT transcription complex subunit 3 isoform X2

  22. XM_054321093.1 → XP_054177068.1  CCR4-NOT transcription complex subunit 3 isoform X5

  23. XM_054321097.1 → XP_054177072.1  CCR4-NOT transcription complex subunit 3 isoform X6

    UniProtKB/Swiss-Prot
    O75175, Q9NZN7, Q9UF76

  24. XM_054321086.1 → XP_054177061.1  CCR4-NOT transcription complex subunit 3 isoform X2

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O75175.1 GenPept UniProtKB/Swiss-Prot:O75175

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