AK5 adenylate kinase 5 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: AK5provided by VGNC
Official Full Name: adenylate kinase 5provided by VGNC
Primary source: VGNC:VGNC:37747
See related: Ensembl:ENSCAFG00845003950
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	6	NC_051810.1 (69869373..70108061, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	6	NC_006588.4 (71941051..72178506, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	6	NC_049227.1 (69806208..70043686, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	6	NC_049266.1 (69374102..69611148, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	6	NC_049747.1 (69320227..69557015, complement)

Chromosome 6 - NC_051810.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables adenylate kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables nucleoside diphosphate kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in ATP metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in nucleoside triphosphate biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: adenylate kinase isoenzyme 5

XP_005622110.1

EC 2.7.4.3

XP_038336217.1

EC 2.7.4.3

XP_038336218.1

EC 2.7.4.3

XP_038336219.1

EC 2.7.4.3

XP_038397560.1

EC 2.7.4.3

XP_038397561.1

EC 2.7.4.3

XP_038461698.1

EC 2.7.4.3

XP_038461699.1

EC 2.7.4.3

XP_038526300.1

EC 2.7.4.3

XP_038526301.1

EC 2.7.4.3

XP_038526302.1

EC 2.7.4.3

XP_547325.4

EC 2.7.4.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051810.1 Reference ROS_Cfam_1.0

Range

69869373..70108061 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038670373.1 → XP_038526301.1 adenylate kinase isoenzyme 5 isoform X3

UniProtKB/TrEMBL

A0A8I3MRL9

Related

ENSCAFP00845005677.1, ENSCAFT00845007120.1

Conserved Domains (2) summary

TIGR01360
Location:350 → 536

aden_kin_iso1; adenylate kinase, isozyme 1 subfamily

cd01428
Location:110 → 283

ADK; Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for ...
XM_038670374.1 → XP_038526302.1 adenylate kinase isoenzyme 5 isoform X1

UniProtKB/TrEMBL

A0A8C0KWQ8

Conserved Domains (2) summary

TIGR01360
Location:310 → 496

aden_kin_iso1; adenylate kinase, isozyme 1 subfamily

cd01428
Location:134 → 245

ADK; Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for ...
XM_038670372.1 → XP_038526300.1 adenylate kinase isoenzyme 5 isoform X2

UniProtKB/TrEMBL

A0A8C0KWQ8, A0A8I3MSE3

Related

ENSCAFP00845005692.1, ENSCAFT00845007146.1

Conserved Domains (2) summary

TIGR01360
Location:374 → 560

aden_kin_iso1; adenylate kinase, isozyme 1 subfamily

cd01428
Location:134 → 307

ADK; Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049266.1 Alternate UMICH_Zoey_3.1

Range

69374102..69611148 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038480290.1 → XP_038336218.1 adenylate kinase isoenzyme 5 isoform X3
XM_038480291.1 → XP_038336219.1 adenylate kinase isoenzyme 5 isoform X1
XM_038480289.1 → XP_038336217.1 adenylate kinase isoenzyme 5 isoform X2

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049747.1 Alternate UNSW_CanFamBas_1.0

Range

69320227..69557015 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038605771.1 → XP_038461699.1 adenylate kinase isoenzyme 5 isoform X3

Conserved Domains (2) summary

TIGR01360
Location:350 → 536

aden_kin_iso1; adenylate kinase, isozyme 1 subfamily

cd01428
Location:110 → 283

ADK; Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for ...
XM_038605770.1 → XP_038461698.1 adenylate kinase isoenzyme 5 isoform X2

Conserved Domains (2) summary

TIGR01360
Location:374 → 560

aden_kin_iso1; adenylate kinase, isozyme 1 subfamily

cd01428
Location:134 → 307

ADK; Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for ...

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049227.1 Alternate UU_Cfam_GSD_1.0

Range

69806208..70043686 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038541633.1 → XP_038397561.1 adenylate kinase isoenzyme 5 isoform X3

UniProtKB/TrEMBL

A0A8I3MRL9

Conserved Domains (2) summary

TIGR01360
Location:350 → 536

aden_kin_iso1; adenylate kinase, isozyme 1 subfamily

cd01428
Location:110 → 283

ADK; Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for ...
XM_038541632.1 → XP_038397560.1 adenylate kinase isoenzyme 5 isoform X2

UniProtKB/TrEMBL

A0A8C0KWQ8, A0A8I3MSE3

Conserved Domains (2) summary

TIGR01360
Location:374 → 560

aden_kin_iso1; adenylate kinase, isozyme 1 subfamily

cd01428
Location:134 → 307

ADK; Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

71941051..72178506 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005622053.4 → XP_005622110.1 adenylate kinase isoenzyme 5 isoform X3

UniProtKB/TrEMBL

A0A8P0PPK9

Conserved Domains (2) summary

cd01428
Location:110 → 283

ADK; Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for ...

cl27057
Location:350 → 536

ADK; Adenylate kinase
XM_547325.7 → XP_547325.4 adenylate kinase isoenzyme 5 isoform X2

UniProtKB/TrEMBL

A0A8C0KWQ8, A0A8P0SPG6

Conserved Domains (2) summary

cd01428
Location:134 → 307

ADK; Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for ...

cl27057
Location:374 → 560

ADK; Adenylate kinase