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CXCR3 C-X-C motif chemokine receptor 3 [ Canis lupus familiaris (dog) ]

Gene ID: 491952, updated on 28-Sep-2021

Summary

Official Symbol
CXCR3provided by VGNC
Official Full Name
C-X-C motif chemokine receptor 3provided by VGNC
Primary source
VGNC:VGNC:39750
See related
EnsemblRapid:ENSCAFG00845019157
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

See CXCR3 in Genome Data Viewer
Location:
chromosome: X
Exon count:
2
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (56851684..56853833, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (46709139..46711288, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (56078430..56080579, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (54818992..54821141, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (56150994..56153143, complement)
105 previous assembly CanFam3.1 (GCF_000002285.3) X NC_006621.3 (55882433..55884582, complement)

Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene O-linked N-acetylglucosamine (GlcNAc) transferase Neighboring gene germ cell nuclear acidic peptidase Neighboring gene uncharacterized protein CXorf49-like Neighboring gene uncharacterized protein CXorf49 homolog

Genomic regions, transcripts, and products

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables C-X-C chemokine binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables C-X-C chemokine receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables signaling receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in angiogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in chemokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of execution phase of apoptosis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of angiogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of cell population proliferation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of chemotaxis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of release of sequestered calcium ion into cytosol ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of leukocyte migration IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
C-X-C chemokine receptor type 3
Names
IP-10 receptor
chemokine (C-X-C motif) receptor 3
interferon-inducible protein 10 receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001011887.3NP_001011887.2  C-X-C chemokine receptor type 3

    Status: VALIDATED

    Source sequence(s)
    JAAUVH010000175
    Related
    ENSCAFP00845026459.1, ENSCAFT00845033811.1
    Conserved Domains (1) summary
    cd15180
    Location:54329
    7tmA_CXCR3; CXC chemokine receptor type 3, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051843.1 Reference ROS_Cfam_1.0

    Range
    56851684..56853833 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049299.1 Alternate UMICH_Zoey_3.1

    Range
    54818992..54821141 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

    Range
    56150994..56153143 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

    Range
    56078430..56080579 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    46709139..46711288 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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