amdhd1 amidohydrolase domain containing 1 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: amdhd1provided by Xenbase
Official Full Name: amidohydrolase domain containing 1provided by Xenbase
Primary source: Xenbase:XB-GENE-5845038
See related: Ensembl:ENSXETG00000021636
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	3	NC_030679.2 (57063313..57073326)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	3	NC_030679.1 (47649471..47659524)

Chromosome 3 - NC_030679.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	IEA Inferred from Electronic Annotation more info
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	IEA Inferred from Electronic Annotation more info
enables imidazolonepropionase activity	IBA Inferred from Biological aspect of Ancestor more info
enables imidazolonepropionase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in histidine catabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within histidine catabolic process to glutamate and formamide	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within histidine catabolic process to glutamate and formate	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within histidine metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: probable imidazolonepropionase

Names: amidohydrolase domain-containing protein 1

NP_001007888.1

EC 3.5.2.7

XP_012814327.1

EC 3.5.2.7

XP_017947532.1

EC 3.5.2.7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001007887.1 → NP_001007888.1 probable imidazolonepropionase

See identical proteins and their annotated locations for NP_001007888.1

Status: PROVISIONAL

Source sequence(s)

BC080159

UniProtKB/Swiss-Prot

Q68EP2

Conserved Domains (1) summary

cd01296
Location:43 → 420

Imidazolone-5PH; Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria, ...

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

Range

57063313..57073326

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_012958873.3 → XP_012814327.1 probable imidazolonepropionase isoform X1

See identical proteins and their annotated locations for XP_012814327.1

UniProtKB/Swiss-Prot

Q68EP2

Related

ENSXETP00000046755.4, ENSXETT00000046755.5

Conserved Domains (1) summary

cd01296
Location:43 → 420

Imidazolone-5PH; Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria, ...
XM_018092043.2 → XP_017947532.1 probable imidazolonepropionase isoform X1

UniProtKB/Swiss-Prot

Q68EP2

Conserved Domains (1) summary

cd01296
Location:43 → 420

Imidazolone-5PH; Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria, ...