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eif4eb eukaryotic translation initiation factor 4eb [ Danio rerio (zebrafish) ]

Gene ID: 493617, updated on 27-Mar-2024

Summary

Official Symbol
eif4ebprovided by ZNC
Official Full Name
eukaryotic translation initiation factor 4ebprovided by ZNC
Primary source
ZFIN:ZDB-GENE-041121-14
See related
Ensembl:ENSDARG00000013274 AllianceGenome:ZFIN:ZDB-GENE-041121-14
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:101581
Summary
Predicted to enable RNA 7-methylguanosine cap binding activity and translation initiation factor activity. Predicted to act upstream of or within translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 4F complex. Is expressed in several structures, including hatching gland; head; optic tectum; polster; and solid lens vesicle. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human EIF4E (eukaryotic translation initiation factor 4E). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See eif4eb in Genome Data Viewer
Location:
chromosome: 13
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (12671534..12681979)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (12539059..12549504)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene alcohol dehydrogenase 8a Neighboring gene family with sequence similarity 241 member A Neighboring gene leucine rich repeat and Ig domain containing 2b Neighboring gene zgc:100846

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA 7-methylguanosine cap binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables translation initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
 
involved_in translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within translational initiation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
part_of eukaryotic translation initiation factor 4F complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
eukaryotic translation initiation factor 4eb

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007777.1NP_001007778.1  eukaryotic translation initiation factor 4eb

    See identical proteins and their annotated locations for NP_001007778.1

    Status: PROVISIONAL

    Source sequence(s)
    BC085374
    UniProtKB/TrEMBL
    Q5RKQ5
    Related
    ENSDARP00000007117.6, ENSDART00000010517.8
    Conserved Domains (1) summary
    pfam01652
    Location:40196
    IF4E; Eukaryotic initiation factor 4E

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    12671534..12681979
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394870.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    110600..121045
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)