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DIABLO diablo IAP-binding mitochondrial protein [ Bos taurus (cattle) ]

Gene ID: 493999, updated on 6-Jun-2024

Summary

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Official Symbol
DIABLOprovided by VGNC
Official Full Name
diablo IAP-binding mitochondrial proteinprovided by VGNC
Primary source
VGNC:VGNC:28061
See related
BGD:BT15940; Ensembl:ENSBTAG00000004199
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
SMAC
Orthologs
human mouse all
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Genomic context

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See DIABLO in Genome Data Viewer
Location:
chromosome: 17
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 17 NC_037344.1 (53156291..53173980)

Chromosome 17 - NC_037344.1Genomic Context describing neighboring genes Neighboring gene VPS33A core subunit of CORVET and HOPS complexes Neighboring gene large ribosomal subunit protein uL6-like Neighboring gene uncharacterized LOC132342613 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 Neighboring gene leucine rich repeat containing 43

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037344.1 Chromosome 17 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC134245

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intrinsic apoptotic signaling pathway in response to oxidative stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuron apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
diablo IAP-binding mitochondrial protein
Names
diablo homolog
second mitochondrial derived activator of caspases

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001045882.2 → NP_001039347.1  diablo IAP-binding mitochondrial protein

    See identical proteins and their annotated locations for NP_001039347.1

    Status: PROVISIONAL

    Source sequence(s)
    BC111127
    UniProtKB/TrEMBL
    A0AAA9T9X9, Q2NL36
    Related
    ENSBTAP00000094825.1, ENSBTAT00000126769.1
    Conserved Domains (1) summary
    pfam09057
    Location:9 → 238
    Smac_DIABLO; Second Mitochondria-derived Activator of Caspases

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037344.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    53156291..53173980
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005217750.5 → XP_005217807.1  diablo IAP-binding mitochondrial protein isoform X3

    See identical proteins and their annotated locations for XP_005217807.1

    Conserved Domains (1) summary
    pfam09057
    Location:1 → 167
    Smac_DIABLO; Second Mitochondria-derived Activator of Caspases

  2. XM_010813884.4 → XP_010812186.1  diablo IAP-binding mitochondrial protein isoform X1

    UniProtKB/TrEMBL
    A0AAA9SMQ0
    Related
    ENSBTAP00000085245.1, ENSBTAT00000102213.1
    Conserved Domains (1) summary
    pfam09057
    Location:9 → 194
    Smac_DIABLO; Second Mitochondria-derived Activator of Caspases

  3. XM_005217748.5 → XP_005217805.1  diablo IAP-binding mitochondrial protein isoform X2

    UniProtKB/TrEMBL
    A0AAA9SMQ0
    Conserved Domains (1) summary
    pfam09057
    Location:9 → 172
    Smac_DIABLO; Second Mitochondria-derived Activator of Caspases

  4. XM_005217751.4 → XP_005217808.1  diablo IAP-binding mitochondrial protein isoform X3

    See identical proteins and their annotated locations for XP_005217808.1

    Conserved Domains (1) summary
    pfam09057
    Location:1 → 167
    Smac_DIABLO; Second Mitochondria-derived Activator of Caspases
Nucleotide Protein Strain
Heading Accession and Version

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