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ORF67 ORF67 [ Human gammaherpesvirus 8 ]

Gene ID: 4961524, updated on 18-Aug-2023

Summary

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Gene symbol
ORF67
Gene description
ORF67
Locus tag
HHV8GK18_gp74
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Human gammaherpesvirus 8 (strain: GK18, type: P, common: Kaposi's sarcoma-associated herpesvirus, acronym: HHV-8, acronym: KSHV, nat-host: Homo sapiens)
Lineage
Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Gammaherpesvirinae; Rhadinovirus
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Genomic context

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Sequence:
NC_009333.1 (111927..114614, complement)

NC_009333.1Genomic Context describing neighboring genes Neighboring gene vIRF-2 Neighboring gene ORF58 Neighboring gene ORF60 Neighboring gene ORF61 Neighboring gene ORF59 Neighboring gene ORF62 Neighboring gene ORF63 Neighboring gene ORF64 Neighboring gene ORF67A Neighboring gene ORF65 Neighboring gene ORF66 Neighboring gene ORF68 Neighboring gene ORF69 Neighboring gene K12

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009333.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. KSHV ORF67 encoded lytic protein localizes on the nuclear membrane and alters emerin distribution. Farina A, et al. Virus Res, 2013 Aug. PMID 23623980
  2. Reconstitution of the Kaposi's sarcoma-associated herpesvirus nuclear egress complex and formation of nuclear membrane vesicles by coexpression of ORF67 and ORF69 gene products. Desai PJ, et al. J Virol, 2012 Jan. PMID 22013050, Free PMC Article
  3. Kaposi's sarcoma-associated herpesvirus immune modulation: an overview. Rezaee SAR, et al. J Gen Virol, 2006 Jul. PMID 16760382
  4. Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes. Davis ZH, et al. Mol Cell, 2015 Jan 22. PMID 25544563, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Immunofluorescence assay and biochemical analysis of infected or transfected cells showed that Kaposi's sarcoma-associated herpesvirus p29 expression resulted in delocalization and hyperphosphorylation of emerin.
    Title: KSHV ORF67 encoded lytic protein localizes on the nuclear membrane and alters emerin distribution.
  2. ORF67 and ORF69 proteins form a complex at the nuclear membrane derived vesicles.
    Title: Reconstitution of the Kaposi's sarcoma-associated herpesvirus nuclear egress complex and formation of nuclear membrane vesicles by coexpression of ORF67 and ORF69 gene products.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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regulatory

  • Loc: c111932-111927 regulatory_class = polyA_signal_sequence

General protein information

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Preferred Names
ORF67
YP_001129424.1
  • herpesvirus core gene UL34 family

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_009333.1 Reference assembly

    Range
    111927..114614 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_001129424.1 ORF67 [Human gammaherpesvirus 8]

    See identical proteins and their annotated locations for YP_001129424.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    F5HA27
    UniProtKB/TrEMBL
    A0A0N9RM30, P88957, Q2HR61, Q76RF3
    Conserved Domains (1) summary
    pfam04541
    Location:5 → 194
    Herpes_U34; Herpesvirus virion protein U34
Nucleotide Protein
Heading Accession and Version

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