proz protein Z, vitamin K-dependent plasma glycoprotein [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: prozprovided by Xenbase
Official Full Name: protein Z, vitamin K-dependent plasma glycoproteinprovided by Xenbase
Primary source: Xenbase:XB-GENE-971425
See related: Ensembl:ENSXETG00000025493
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	2	NC_030678.2 (116052325..116060162, complement)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	2	NC_030678.1 (112493548..112501386, complement)

Chromosome 2 - NC_030678.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables serine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within blood coagulation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within proteolysis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: vitamin K-dependent protein Z

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001122717.1 → NP_001116189.1 vitamin K-dependent protein Z precursor

Status: VALIDATED

Source sequence(s)

BC088065, BC160557

UniProtKB/TrEMBL

A0A6I8PTX3, Q5M8E7

Related

ENSXETP00000058417.1, ENSXETT00000064858.3

Conserved Domains (4) summary

smart00069
Location:22 → 85

GLA; Domain containing Gla (gamma-carboxyglutamate) residues

cd00054
Location:92 → 123

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

pfam14670
Location:136 → 167

FXa_inhibition; Coagulation Factor Xa inhibitory site

cl21584
Location:197 → 414

Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...