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serpinb1 serpin family B member 1 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 496899, updated on 5-Mar-2024

Summary

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Official Symbol
serpinb1provided by Xenbase
Official Full Name
serpin family B member 1provided by Xenbase
Primary source
Xenbase:XB-GENE-1217264
See related
Ensembl:ENSXETG00000027588
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
lei; pi2; mnei; m/nei; elanh2
Orthologs
human all
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Genomic context

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See serpinb1 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
7
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 6 NC_030682.2 (86027919..86042129)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 6 NC_030682.1 (52367252..52382353, complement)

Chromosome 6 - NC_030682.2Genomic Context describing neighboring genes Neighboring gene serpin peptidase inhibitor, clade B (ovalbumin), member 10 Neighboring gene serpin family B member 6 Neighboring gene Werner helicase interacting protein 1 Neighboring gene myosin light chain kinase family member 4 Neighboring gene uncharacterized LOC116411474

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables peptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in negative regulation of endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
leukocyte elastase inhibitor
Names
serpin B1
serpin peptidase inhibitor, clade B (ovalbumin), member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001011419.1 → NP_001011419.1  leukocyte elastase inhibitor

    See identical proteins and their annotated locations for NP_001011419.1

    Status: PROVISIONAL

    Source sequence(s)
    BC088021
    UniProtKB/Swiss-Prot
    Q5I0S8
    Conserved Domains (1) summary
    cl00137
    Location:4 → 377
    SERPIN; SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030682.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    86027919..86042129
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012964624.3 → XP_012820078.2  leukocyte elastase inhibitor isoform X1

    Related
    ENSXETP00000001376.4, ENSXETT00000001376.5
    Conserved Domains (1) summary
    cd19560
    Location:1 → 377
    serpinB1_LEI; serpin family B member 1 (serpin B1), leukocyte elastase inhibitor (LEI)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5I0S8.1 GenPept UniProtKB/Swiss-Prot:Q5I0S8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.