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Arl5c ADP-ribosylation factor like GTPase 5C [ Rattus norvegicus (Norway rat) ]

Gene ID: 497990, updated on 13-Apr-2024

Summary

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Official Symbol
Arl5cprovided by RGD
Official Full Name
ADP-ribosylation factor like GTPase 5Cprovided by RGD
Primary source
RGD:1563128
See related
Ensembl:ENSRNOG00000036880 AllianceGenome:RGD:1563128
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1563128
Summary
Predicted to enable GTP binding activity. Predicted to be involved in intracellular protein transport; protein localization to Golgi membrane; and vesicle-mediated transport. Predicted to be active in trans-Golgi network. Orthologous to human ARL5C (ADP ribosylation factor like GTPase 5C). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 581.0) and Spleen (RPKM 153.5) See more
Orthologs
human mouse all
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Genomic context

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Location:
10q31
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (83481540..83492915, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (82985213..82993425, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (85939836..85948131, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene transfer RNA cysteine (anticodon GCA) 36 Neighboring gene transfer RNA cysteine (anticodon GCA) 37 Neighboring gene uncharacterized LOC134480866 Neighboring gene calcium voltage-gated channel auxiliary subunit beta 1 Neighboring gene ribosomal protein L19 Neighboring gene SH3 and cysteine rich domain 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein localization to Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
putative ADP-ribosylation factor-like protein 5C
Names
ADP-ribosylation factor-like 5C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109046.2 → NP_001102516.1  putative ADP-ribosylation factor-like protein 5C

    See identical proteins and their annotated locations for NP_001102516.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A0A0G2JUX1, A6HIP1, D3ZES1
    Related
    ENSRNOP00000029510.4, ENSRNOT00000037318.5
    Conserved Domains (1) summary
    cd04153
    Location:3 → 175
    Arl5_Arl8; Arf-like 5 (Arl5) and 8 (Arl8) GTPases

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    83481540..83492915 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039086633.2 → XP_038942561.1  putative ADP-ribosylation factor-like protein 5C isoform X2

    Conserved Domains (1) summary
    cl38936
    Location:79 → 189
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. XM_039086632.2 → XP_038942560.1  putative ADP-ribosylation factor-like protein 5C isoform X1

    Conserved Domains (1) summary
    cl38936
    Location:79 → 217
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_063269660.1 → XP_063125730.1  putative ADP-ribosylation factor-like protein 5C isoform X4

  4. XM_039086634.2 → XP_038942562.1  putative ADP-ribosylation factor-like protein 5C isoform X3

    Conserved Domains (1) summary
    cl38936
    Location:79 → 130
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein Strain
Heading Accession and Version

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