Format

Send to:

Choose Destination

Prxl2c peroxiredoxin like 2C [ Rattus norvegicus (Norway rat) ]

Gene ID: 498685, updated on 5-Jun-2021

Summary

Official Symbol
Prxl2cprovided by RGD
Official Full Name
peroxiredoxin like 2Cprovided by RGD
Primary source
RGD:1589650
See related
Ensembl:ENSRNOG00000018886
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Aaed1
Expression
Biased expression in Kidney (RPKM 95.0), Heart (RPKM 89.8) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Prxl2c in Genome Data Viewer
Location:
17p14
Exon count:
9
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (812199..844075)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (1798224..1830011, complement)

Chromosome 17 - NC_051352.1Genomic Context describing neighboring genes Neighboring gene serine/arginine-rich splicing factor 3-like Neighboring gene cathepsin L Neighboring gene U6 spliceosomal RNA Neighboring gene transfer RNA serine (anticodon AGA) Neighboring gene cell division cycle 14B Neighboring gene U4 spliceosomal RNA Neighboring gene hyaluronan binding protein 4

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables antioxidant activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular oxidant detoxification IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of glycolytic process ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
peroxiredoxin-like 2C
Names
AhpC/TSA antioxidant enzyme domain containing 1
thioredoxin-like protein AAED1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109114.1NP_001102584.1  peroxiredoxin-like 2C

    See identical proteins and their annotated locations for NP_001102584.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474087
    UniProtKB/TrEMBL
    D3ZAK1
    Related
    ENSRNOP00000062637.1, ENSRNOT00000066230.1
    Conserved Domains (1) summary
    cd02970
    Location:34141
    PRX_like2; Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051352.1 Reference mRatBN7.2 Primary Assembly

    Range
    812199..844075
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039095988.1XP_038951916.1  peroxiredoxin-like 2C isoform X3

    Conserved Domains (1) summary
    cd02970
    Location:34134
    PRX_like2; Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these ...
  2. XM_039095987.1XP_038951915.1  peroxiredoxin-like 2C isoform X1

    Conserved Domains (1) summary
    cd02970
    Location:34192
    PRX_like2; Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these ...
  3. XM_006253497.4XP_006253559.1  peroxiredoxin-like 2C isoform X4

    Conserved Domains (1) summary
    cd02970
    Location:34168
    PRX_like2; Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these ...
  4. XM_006253495.4XP_006253557.1  peroxiredoxin-like 2C isoform X2

    See identical proteins and their annotated locations for XP_006253557.1

    Conserved Domains (1) summary
    cd02970
    Location:34195
    PRX_like2; Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these ...

RNA

  1. XR_005495312.1 RNA Sequence

Support Center