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Idnk Idnk, gluconokinase [ Rattus norvegicus (Norway rat) ]

Gene ID: 498695, updated on 11-Apr-2024

Summary

Official Symbol
Idnkprovided by RGD
Official Full Name
Idnk, gluconokinaseprovided by RGD
Primary source
RGD:1564546
See related
Ensembl:ENSRNOG00000019519 AllianceGenome:RGD:1564546
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable gluconokinase activity. Predicted to be involved in D-gluconate catabolic process. Orthologous to human IDNK (IDNK gluconokinase). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 30.6), Liver (RPKM 18.5) and 9 other tissues See more
Orthologs
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Genomic context

Location:
17p14
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (6489397..6496520, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (6483575..6490780, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (6885323..6892603, complement)

Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD113/SNORD114 family Neighboring gene ubiquilin 1 Neighboring gene uncharacterized LOC134482668 Neighboring gene heterogeneous nuclear ribonucleoprotein A0

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Clone Names

  • MGC125086

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables gluconokinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in D-gluconate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in D-gluconate catabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in biological_process ND
No biological Data available
more info
 

General protein information

Preferred Names
probable gluconokinase
Names
gluconate kinase
idnK, gluconokinase homolog
NP_001032439.1
XP_006253625.1
XP_006253626.1
XP_038951917.1
XP_038951918.2
XP_063132752.1
XP_063132754.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037362.1NP_001032439.1  probable gluconokinase

    See identical proteins and their annotated locations for NP_001032439.1

    Status: PROVISIONAL

    Source sequence(s)
    BC107923
    UniProtKB/Swiss-Prot
    Q32PY9
    UniProtKB/TrEMBL
    A0A8I5Y4K0, A6KAL2
    Related
    ENSRNOP00000082724.1, ENSRNOT00000116956.1
    Conserved Domains (2) summary
    COG0703
    Location:10185
    AroK; Shikimate kinase [Amino acid transport and metabolism]
    COG3265
    Location:10185
    GntK; Gluconate kinase [Carbohydrate transport and metabolism]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086035.1 Reference GRCr8

    Range
    6489397..6496520 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039095990.2XP_038951918.2  probable gluconokinase isoform X4

  2. XM_006253563.5XP_006253625.1  probable gluconokinase isoform X1

    UniProtKB/TrEMBL
    A0A8I5Y4K0, A0A8I6AFF0
    Related
    ENSRNOP00000091550.1
    Conserved Domains (1) summary
    cl17190
    Location:38196
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
  3. XM_006253564.5XP_006253626.1  probable gluconokinase isoform X6

    UniProtKB/TrEMBL
    A0A8L2QEZ2
    Related
    ENSRNOP00000026407.5
    Conserved Domains (1) summary
    cl17190
    Location:655
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
  4. XM_039095989.2XP_038951917.1  probable gluconokinase isoform X2

    UniProtKB/TrEMBL
    A0A8I5Y4K0
    Conserved Domains (1) summary
    cl17190
    Location:1139
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
  5. XM_063276682.1XP_063132752.1  probable gluconokinase isoform X3

    UniProtKB/TrEMBL
    A6KAL3
  6. XM_063276684.1XP_063132754.1  probable gluconokinase isoform X5