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Sertad3 SERTA domain containing 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 499108, updated on 5-Mar-2024

Summary

Official Symbol
Sertad3provided by RGD
Official Full Name
SERTA domain containing 3provided by RGD
Primary source
RGD:1564271
See related
Ensembl:ENSRNOG00000037690 AllianceGenome:RGD:1564271
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in positive regulation of transcription, DNA-templated. Predicted to act upstream of or within negative regulation of cell growth. Predicted to be active in nucleus. Orthologous to human SERTAD3 (SERTA domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Spleen (RPKM 30.8), Thymus (RPKM 29.0) and 9 other tissues See more
Orthologs
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Genomic context

Location:
1q21
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (91891141..91894861)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (82763535..82767271)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (84280945..84284681)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene spectrin, beta, non-erythrocytic 4 Neighboring gene biliverdin reductase B Neighboring gene SERTA domain containing 1 Neighboring gene transmembrane protein 258, pseudogene 4 Neighboring gene periaxin

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
SERTA domain-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017513.1NP_001017513.1  SERTA domain-containing protein 3

    See identical proteins and their annotated locations for NP_001017513.1

    Status: PROVISIONAL

    Source sequence(s)
    BC091229
    UniProtKB/TrEMBL
    A0A8I5ZNI4, Q5BK27
    Related
    ENSRNOP00000081979.1, ENSRNOT00000114037.1
    Conserved Domains (1) summary
    pfam06031
    Location:3468
    SERTA; SERTA motif

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    91891141..91894861
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006228582.2XP_006228644.1  SERTA domain-containing protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006228644.1

    UniProtKB/TrEMBL
    A0A8I5ZNI4, Q5BK27
    Related
    ENSRNOP00000079647.1
    Conserved Domains (1) summary
    pfam06031
    Location:3468
    SERTA; SERTA motif