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Gstt3 glutathione S-transferase, theta 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 499422, updated on 13-Apr-2024

Summary

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Official Symbol
Gstt3provided by RGD
Official Full Name
glutathione S-transferase, theta 3provided by RGD
Primary source
RGD:1562732
See related
Ensembl:ENSRNOG00000001242 AllianceGenome:RGD:1562732
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1562732
Summary
Predicted to enable glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 991.7), Adrenal (RPKM 614.9) and 5 other tissues See more
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Genomic context

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Location:
20p12
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (12873618..12881974)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (12875184..12882540)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (13817795..13825475)

Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene glutathione S-transferase, theta 4 Neighboring gene glutathione S-transferase theta 1 Neighboring gene uncharacterized LOC134483890 Neighboring gene D-dopachrome tautomerase Neighboring gene calcineurin binding protein 1 Neighboring gene uncharacterized LOC102556116

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Expression levels of pituitary tumor transforming 1 and glutathione-S-transferase theta 3 are associated with the individual susceptibility to D-galactosamine-induced hepatotoxicity. Yun JW, et al. Toxicol Appl Pharmacol, 2010 Jan 1. PMID 19800905
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Gstt3 could predict inter-individual susceptibility to D-galactosamine induced hepatotoxicity
    Title: Expression levels of pituitary tumor transforming 1 and glutathione-S-transferase theta 3 are associated with the individual susceptibility to D-galactosamine-induced hepatotoxicity.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

General protein information

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Preferred Names
glutathione S-transferase, theta 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399042.1 → NP_001385971.1  glutathione S-transferase, theta 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000020
    Related
    ENSRNOP00000078933.1, ENSRNOT00000098201.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086038.1 Reference GRCr8

    Range
    12873618..12881974
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063279467.1 → XP_063135537.1  glutathione S-transferase, theta 3 isoform X2

  2. XM_063279466.1 → XP_063135536.1  glutathione S-transferase, theta 3 isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001137643.1: Suppressed sequence

    Description
    NM_001137643.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

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