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COX7A Cytochrome c oxidase subunit 7A [ Drosophila melanogaster (fruit fly) ]

Gene ID: 50002, updated on 14-Jun-2022

Summary

Official Symbol
COX7Aprovided by FlyBase
Official Full Name
Cytochrome c oxidase subunit 7Aprovided by FlyBase
Primary source
FLYBASE:FBgn0040529
Locus tag
Dmel_CG9603
See related
AllianceGenome:FB:FBgn0040529
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG9603; Cox7a; COXJ; COXK; Dmel\CG9603; VIIa
Summary
Predicted to enable cytochrome-c oxidase activity. Predicted to be involved in mitochondrial respirasome assembly and regulation of oxidative phosphorylation. Located in mitochondrion. Is expressed in adult head and adult heart. Used to study cytochrome-c oxidase deficiency disease. Orthologous to several human genes including COX7A1 (cytochrome c oxidase subunit 7A1) and COX7A2 (cytochrome c oxidase subunit 7A2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See COX7A in Genome Data Viewer
Location:
84F13-84F13; 3-48 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8339944..8341043, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4165666..4166765, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Pox meso Neighboring gene Odorant receptor 85a Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ADP ribosylation factor-like 2 Neighboring gene Cytochrome c oxidase subunit 7A-like

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
cytochrome c oxidase subunit 7A
Names
CG9603-PA
CG9603-PB
COX7A-PA
COX7A-PB
cytochrome c oxidase VIIa
cytochrome c oxidase polypeptide VIIa
NP_001246986.1
NP_652184.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    8339944..8341043 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143927.4NP_652184.2  cytochrome c oxidase subunit 7A, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_652184.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VHS2
    Related
    FBpp0081344, FBtr0081855
    Conserved Domains (1) summary
    cd00928
    Location:3185
    Cyt_c_Oxidase_VIIa; Cytochrome c oxidase subunit VIIa. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...
  2. NM_001260057.1NP_001246986.1  cytochrome c oxidase subunit 7A, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246986.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K6C3
    Related
    FBpp0296960, FBtr0305680
    Conserved Domains (1) summary
    cd00928
    Location:4094
    Cyt_c_Oxidase_VIIa; Cytochrome c oxidase subunit VIIa. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...