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CG45263 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 50003, updated on 10-May-2024

Summary

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Official Symbol
CG45263provided by FlyBase
Primary source
FLYBASE:FBgn0266801
Locus tag
Dmel_CG45263
See related
AllianceGenome:FB:FBgn0266801
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
43462; anon-EST:Posey178; BcDNA:AT05815; BcDNA:GH22170; CG11718; CG11729; CG11730; CG11731; CG11733; CG31264; CG31369; CG31462; CG42285; CG42286; CG43462; CT32186; Dmel\CG45263; GH22170; GS3056; MRE1
Old locus tag
Dmel_CG11718; Dmel_CG31369; Dmel_CG31462; Dmel_CG42285; Dmel_CG42286; Dmel_CG43462
Summary
Predicted to enable cell adhesion molecule binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be active in cell-cell junction. Predicted to be integral component of plasma membrane. Is expressed in several structures, including dorsal ectoderm; extended germ band embryo; gastrula embryo; presumptive embryonic/larval system; and sensory nervous system primordium. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See CG45263 in Genome Data Viewer
Location:
84F15-85A2; 3-48 cM
Exon count:
18
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8364328..8477617, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4190050..4303339, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene veneno Neighboring gene steamer duck Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46126 Neighboring gene Odorant-binding protein 85a Neighboring gene long non-coding RNA:CR46125 Neighboring gene Odorant receptor 85b Neighboring gene Odorant receptor 85c

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila PQBP1 regulates learning acquisition at projection neurons in aversive olfactory conditioning. Tamura T, et al. J Neurosci, 2010 Oct 20. PMID 20962230, Free PMC Article
  2. Classifying Drosophila Olfactory Projection Neuron Subtypes by Single-Cell RNA Sequencing. Li H, et al. Cell, 2017 Nov 16. PMID 29149607, Free PMC Article
  3. Cross-phenotype association tests uncover genes mediating nutrient response in Drosophila. Nelson CS, et al. BMC Genomics, 2016 Nov 4. PMID 27809764, Free PMC Article
  4. Application of the gene search system to screen for longevity genes in Drosophila. Seong KH, et al. Biogerontology, 2001. PMID 11708722
  5. Target genes of Dpp/BMP signaling pathway revealed by transcriptome profiling in the early D.melanogaster embryo. Dominguez C, et al. Gene, 2016 Oct 10. PMID 27397649

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. these findings identify dPQBP1 as a novel gene regulating learning acquisition at projection neurons
    Title: Drosophila PQBP1 regulates learning acquisition at projection neurons in aversive olfactory conditioning.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables cell adhesion molecule binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cell-cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cell-cell junction IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG45263-PB
CG45263-PC
CG45263-PD
CG45263-PE
CG45263-PF
CG45263-PG
mRNA-like ncRNA in embryogenesis 1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    8364328..8477617 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001260059.2 → NP_001246988.1  uncharacterized protein Dmel_CG45263, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246988.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K609
    Conserved Domains (4) summary
    smart00408
    Location:302 → 357
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:478 → 570
    IG_like; Immunoglobulin like
    pfam07679
    Location:53 → 149
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:198 → 281
    Ig; Immunoglobulin domain

  2. NM_001260060.2 → NP_001246989.1  uncharacterized protein Dmel_CG45263, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246989.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K642
    Conserved Domains (4) summary
    smart00408
    Location:302 → 357
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:478 → 570
    IG_like; Immunoglobulin like
    pfam07679
    Location:53 → 149
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:198 → 281
    Ig; Immunoglobulin domain

  3. NM_001316568.1 → NP_001303497.1  uncharacterized protein Dmel_CG45263, isoform F [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A126GUR3, B5X504
    Conserved Domains (4) summary
    smart00408
    Location:302 → 357
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:478 → 570
    IG_like; Immunoglobulin like
    pfam07679
    Location:53 → 149
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:198 → 281
    Ig; Immunoglobulin domain

  4. NM_169223.4 → NP_731247.3  uncharacterized protein Dmel_CG45263, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_731247.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    B5X504, Q9VHQ8
    Conserved Domains (4) summary
    smart00408
    Location:302 → 357
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:478 → 570
    IG_like; Immunoglobulin like
    pfam07679
    Location:53 → 149
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:198 → 281
    Ig; Immunoglobulin domain

  5. NM_169222.3 → NP_731246.2  uncharacterized protein Dmel_CG45263, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_731246.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VHR2
    Conserved Domains (4) summary
    smart00408
    Location:302 → 357
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:478 → 570
    IG_like; Immunoglobulin like
    pfam07679
    Location:53 → 149
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:198 → 281
    Ig; Immunoglobulin domain

  6. NM_001316569.1 → NP_001303498.1  uncharacterized protein Dmel_CG45263, isoform G [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A126GUS1, B5X504
    Conserved Domains (4) summary
    smart00408
    Location:302 → 357
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:478 → 570
    IG_like; Immunoglobulin like
    pfam07679
    Location:53 → 149
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:198 → 281
    Ig; Immunoglobulin domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4K609 A0A0B4K609
A0A0B4K642 A0A0B4K642
A0A126GUR3 A0A126GUR3
A0A126GUS1 A0A126GUS1
Q8T916 Q8T916
Q95T48 Q95T48
Q9N9Z4 Q9N9Z4
Q9VHQ8 Q9VHQ8
Q9VHR2 Q9VHR2

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