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C2cd6 C2 calcium dependent domain containing 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 501147, updated on 6-Jun-2024

Summary

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Symbol
C2cd6provided by RGD
Full Name
C2 calcium dependent domain containing 6provided by RGD
Primary source
RGD:1565450
See related
Ensembl:ENSRNOG00000012637 AllianceGenome:RGD:1565450
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Als2cr11
Summary
Orthologous to human C2CD6 (C2 calcium dependent domain containing 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 588.3) See more
Orthologs
human mouse all
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Genomic context

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See C2cd6 in Genome Data Viewer
Location:
9q31
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (67929069..68024993, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (60434926..60530842, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (65817039..65879564, complement)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120094796 Neighboring gene trafficking kinesin protein 2 Neighboring gene transfer RNA valine (anticodon AAC) 15 Neighboring gene STE20 related adaptor beta Neighboring gene uncharacterized LOC120094795 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene transmembrane protein 237 Neighboring gene mitochondrial intermembrane space import and assembly protein 40-like Neighboring gene MAGUK p55 scaffold protein 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in flagellated sperm motility ISO
Inferred from Sequence Orthology
more info
  
involved_in sperm capacitation ISO
Inferred from Sequence Orthology
more info
  
involved_in spermatogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in vesicle-mediated transport to the plasma membrane ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of CatSper complex ISO
Inferred from Sequence Orthology
more info
  
located_in sperm principal piece ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
cation channel sperm-associated targeting subunit tau
Names
C2 calcium-dependent domain-containing protein 6
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11
amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein
amyotrophic lateral sclerosis 2 chromosome region, candidate 11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024363.1 → NP_001019534.2  cation channel sperm-associated targeting subunit tau isoform 1

    Status: VALIDATED

    Source sequence(s)
    BC083917
    UniProtKB/TrEMBL
    F7ENY6, Q5XHY2
    Conserved Domains (1) summary
    pfam15729
    Location:129 → 537
    ALS2CR11; Amyotrophic lateral sclerosis 2 candidate 11

  2. NM_001409059.1 → NP_001395988.1  cation channel sperm-associated targeting subunit tau isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    A0A8I5ZTA5, A0A8I6G3E6
    Related
    ENSRNOP00000078612.1, ENSRNOT00000103146.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    67929069..68024993 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039084092.2 → XP_038940020.1  cation channel sperm-associated targeting subunit tau isoform X1

    Conserved Domains (1) summary
    COG5099
    Location:248 → 682
    COG5099; RNA-binding protein of the Puf family, translational repressor [Translation, ribosomal structure and biogenesis]

  2. XM_039084093.2 → XP_038940021.1  cation channel sperm-associated targeting subunit tau isoform X2

    Conserved Domains (1) summary
    COG5099
    Location:155 → 589
    COG5099; RNA-binding protein of the Puf family, translational repressor [Translation, ribosomal structure and biogenesis]

  3. XM_039084094.2 → XP_038940022.1  cation channel sperm-associated targeting subunit tau isoform X2

    Conserved Domains (1) summary
    COG5099
    Location:155 → 589
    COG5099; RNA-binding protein of the Puf family, translational repressor [Translation, ribosomal structure and biogenesis]

  4. XM_039084095.2 → XP_038940023.1  cation channel sperm-associated targeting subunit tau isoform X4

    Conserved Domains (1) summary
    pfam15729
    Location:129 → 537
    ALS2CR11; Amyotrophic lateral sclerosis 2 candidate 11

  5. XM_017596604.3 → XP_017452093.1  cation channel sperm-associated targeting subunit tau isoform X3

Nucleotide Protein Strain
Heading Accession and Version

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