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Cesl1 carboxylesterase-like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 501232, updated on 29-Feb-2024

Summary

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Official Symbol
Cesl1provided by RGD
Official Full Name
carboxylesterase-like 1provided by RGD
Primary source
RGD:1565666
See related
Ensembl:ENSRNOG00000070517 AllianceGenome:RGD:1565666
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable methyl indole-3-acetate esterase activity. Predicted to be located in endoplasmic reticulum lumen. Orthologous to human CES1 (carboxylesterase 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See Cesl1 in Genome Data Viewer
Location:
19q11
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (38554365..38612663, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (22670709..23006329, complement)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene carboxylesterase 1E-like Neighboring gene KH homology domain-containing protein 1-like Neighboring gene disks large homolog 5-like Neighboring gene zinc finger CCCH-type containing, antiviral 1, pseudogene 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Rat kidney carboxylesterase. Cloning, sequencing, cellular localization, and relationship to rat liver hydrolase. Yan B, et al. J Biol Chem, 1994 Nov 25. PMID 7961958
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables carboxylesterase activity IEA
Inferred from Electronic Annotation
more info
  
enables carboxylic ester hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum lumen IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
liver carboxylesterase B-1
Names
liver microsomal carboxylesterase
NP_001019536.1
XP_038953872.1
XP_038953873.1
XP_063134329.1
XP_063134330.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024365.1 → NP_001019536.1  liver carboxylesterase B-1 precursor

    See identical proteins and their annotated locations for NP_001019536.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079129
    UniProtKB/Swiss-Prot
    Q63010, Q6AYA3, Q9QUX6
    UniProtKB/TrEMBL
    F1LLV6, M0R7R1
    Related
    ENSRNOP00000065493.3, ENSRNOT00000074070.3
    Conserved Domains (2) summary
    COG0657
    Location:121 → 234
    Aes; Acetyl esterase/lipase [Lipid transport and metabolism]
    pfam00135
    Location:24 → 545
    COesterase; Carboxylesterase family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    38554365..38612663 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063278260.1 → XP_063134330.1  liver carboxylesterase B-1 isoform X3

  2. XM_063278259.1 → XP_063134329.1  liver carboxylesterase B-1 isoform X1

  3. XM_039097945.2 → XP_038953873.1  liver carboxylesterase B-1 isoform X2

    UniProtKB/TrEMBL
    A0A8I6A7X1
    Conserved Domains (1) summary
    pfam00135
    Location:14 → 537
    COesterase; Carboxylesterase family

  4. XM_039097944.1 → XP_038953872.1  liver carboxylesterase B-1 isoform X2

    UniProtKB/TrEMBL
    A0A8I6A7X1
    Conserved Domains (1) summary
    pfam00135
    Location:14 → 537
    COesterase; Carboxylesterase family

RNA

  1. XR_010060021.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q63010.1 GenPept UniProtKB/Swiss-Prot:Q63010

Gene LinkOut

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