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Nemp2 nuclear envelope integral membrane protein 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 503257, updated on 5-Mar-2024

Summary

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Symbol
Nemp2provided by RGD
Full Name
nuclear envelope integral membrane protein 2provided by RGD
Primary source
RGD:1560421
See related
Ensembl:ENSRNOG00000012924 AllianceGenome:RGD:1560421
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Tmem194b; RGD1560421
Summary
Predicted to be located in nuclear inner membrane. Predicted to be integral component of membrane. Predicted to be active in nuclear envelope. Orthologous to human NEMP2 (nuclear envelope integral membrane protein 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 63.4), Spleen (RPKM 45.5) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
9q22
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (56353233..56372586, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (48861252..48880565, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (53713598..53732858, complement)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene BCL2 interacting protein 3, pseudogene 1 Neighboring gene major facilitator superfamily domain containing 6 Neighboring gene developmental pluripotency-associated protein 3-like Neighboring gene Ngfi-A binding protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
is_active_in nuclear envelope IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nuclear inner membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
nuclear envelope integral membrane protein 2
Names
transmembrane protein 194B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134642.1 → NP_001128114.1  nuclear envelope integral membrane protein 2 precursor

    See identical proteins and their annotated locations for NP_001128114.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473965
    UniProtKB/Swiss-Prot
    P0C8N6
    UniProtKB/TrEMBL
    A6INV9
    Related
    ENSRNOP00000032860.3, ENSRNOT00000029204.4
    Conserved Domains (1) summary
    pfam10225
    Location:142 → 389
    DUF2215; Uncharacterized conserved protein (DUF2215)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    56353233..56372586 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039084132.2 → XP_038940060.1  nuclear envelope integral membrane protein 2 isoform X1

    Conserved Domains (1) summary
    pfam10225
    Location:142 → 376
    NEMP; NEMP family

  2. XM_039084133.2 → XP_038940061.1  nuclear envelope integral membrane protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8I6G4K5, A6INW2
    Related
    ENSRNOP00000079039.1
    Conserved Domains (1) summary
    pfam10225
    Location:142 → 203
    NEMP; NEMP family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0C8N6.1 GenPept UniProtKB/Swiss-Prot:P0C8N6

Gene LinkOut

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