U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ear14 eosinophil-associated, ribonuclease A family, member 14 [ Mus musculus (house mouse) ]

Gene ID: 503847, updated on 8-Feb-2024

Summary

Official Symbol
Ear14provided by MGI
Official Full Name
eosinophil-associated, ribonuclease A family, member 14provided by MGI
Primary source
MGI:MGI:3528616
See related
Ensembl:ENSMUSG00000050766 AllianceGenome:MGI:3528616
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable ribonuclease activity. Predicted to be involved in chemotaxis and innate immune response in mucosa. Predicted to be active in extracellular space. Orthologous to human RNASE2 (ribonuclease A family member 2). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Ear14 in Genome Data Viewer
Location:
14 C1; 14 26.42 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (51441152..51441613)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (51203695..51204156)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene eosinophil-associated, ribonuclease A family, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_36667 Neighboring gene STARR-seq mESC enhancer starr_36668 Neighboring gene angiogenin, ribonuclease A family, member 2 Neighboring gene STARR-seq mESC enhancer starr_36669 Neighboring gene STARR-seq mESC enhancer starr_36670 Neighboring gene ribonuclease, RNase A family, 2A (liver, eosinophil-derived neurotoxin) Neighboring gene predicted gene 7106

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA nuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA nuclease activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in defense response to Gram-positive bacterium IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in innate immune response in mucosa IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
eosinophil-associated, ribonuclease A family, member 14

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017389.2NP_059085.2  eosinophil-associated, ribonuclease A family, member 14 precursor

    See identical proteins and their annotated locations for NP_059085.2

    Status: PROVISIONAL

    Source sequence(s)
    AY665809
    Consensus CDS
    CCDS88652.1
    UniProtKB/TrEMBL
    Q5GAN2, W0UTF4
    Related
    ENSMUSP00000056293.2, ENSMUST00000049559.2
    Conserved Domains (1) summary
    pfam00074
    Location:29150
    RnaseA; Pancreatic ribonuclease

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    51441152..51441613
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)