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SPOCK3 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 [ Homo sapiens (human) ]

Gene ID: 50859, updated on 11-Apr-2024

Summary

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Official Symbol
SPOCK3provided by HGNC
Official Full Name
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3provided by HGNC
Primary source
HGNC:HGNC:13565
See related
Ensembl:ENSG00000196104 MIM:607989; AllianceGenome:HGNC:13565
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TES-3; TICN3; HSAJ1454
Summary
This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Expression
Biased expression in brain (RPKM 28.5), prostate (RPKM 28.2) and 2 other tissues See more
Orthologs
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Genomic context

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Location:
4q32.3
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (166733384..167234945, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (170090608..170592260, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (167654535..168155645, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105377521 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr4:166888016-166889215 Neighboring gene Sharpr-MPRA regulatory region 2915 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr4:166963784-166964983 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22120 Neighboring gene tolloid like 1 Neighboring gene RNA, 5S ribosomal pseudogene 170 Neighboring gene Sharpr-MPRA regulatory region 13283 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_75833 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_75852 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_75875 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_75970 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_75989 Neighboring gene Sharpr-MPRA regulatory region 523 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_76035 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:167491405-167492062 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:167490745-167491404 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22121 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:167636733-167637577 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:167637578-167638421 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:167642620-167643500 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22122 Neighboring gene NANOG hESC enhancer GRCh37_chr4:167796983-167797484 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15787 Neighboring gene RNA, 5S ribosomal pseudogene 171 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22123 Neighboring gene RNA, 7SL, cytoplasmic 776, pseudogene Neighboring gene MED14-independent group 3 enhancer GRCh37_chr4:168508591-168509790 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_76084 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_76088 Neighboring gene PHB1 pseudogene 14

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. SPOCK3, a risk gene for adult ADHD and personality disorders. Weber H, et al. Eur Arch Psychiatry Clin Neurosci, 2014 Aug. PMID 24292267
  2. Testican 3 expression in adult T-cell leukemia. Kamioka M, et al. Leuk Res, 2009 Jul. PMID 19144404
  3. Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Debette S, et al. Biol Psychiatry, 2015 Apr 15. PMID 25648963, Free PMC Article
  4. Suppression of membrane-type 1 matrix metalloproteinase (MMP)-mediated MMP-2 activation and tumor invasion by testican 3 and its splicing variant gene product, N-Tes. Nakada M, et al. Cancer Res, 2001 Dec 15. PMID 11751414
  5. Testican 2 abrogates inhibition of membrane-type matrix metalloproteinases by other testican family proteins. Nakada M, et al. Cancer Res, 2003 Jun 15. PMID 12810672

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Mechanism of prognostic marker SPOCK3 affecting malignant progression of prostate cancer and construction of prognostic model.
    Title: Mechanism of prognostic marker SPOCK3 affecting malignant progression of prostate cancer and construction of prognostic model.
  2. associations, near SPOCK3 were identified and other putative modulators of memory performance were revealed by a
    Title: Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.
  3. The results of this study suggest that SPOCK3 may modify the genetic risk for Attention-deficit/hyperactivity disorder and personality disorders
    Title: SPOCK3, a risk gene for adult ADHD and personality disorders.
  4. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
    Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
  5. High expression of testican 3 is associated with adult T-cell leukemia.
    Title: Testican 3 expression in adult T-cell leukemia.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.
EBI GWAS Catalog
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables glycosaminoglycan binding IEA
Inferred from Electronic Annotation
more info
  
enables metalloendopeptidase inhibitor activity TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of cell motility TAS
Traceable Author Statement
more info
 PubMed 
involved_in negative regulation of endopeptidase activity TAS
Traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
testican-3
Names
SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_030414.1 RefSeqGene

    Range
    5097..506207
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001040159.2 → NP_001035249.1  testican-3 isoform 1 precursor

    See identical proteins and their annotated locations for NP_001035249.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) lacks an alternate in-frame exon compared to variant 2. The resulting isoform (1) has the same N- and C-termini but is shorter compared to isoform 2.
    Source sequence(s)
    AC020599, BC003017
    Consensus CDS
    CCDS34095.1
    UniProtKB/TrEMBL
    B4DFW5
    Related
    ENSP00000350153.4, ENST00000357545.9
    Conserved Domains (3) summary
    smart00280
    Location:137 → 180
    KAZAL; Kazal type serine protease inhibitors
    cd00191
    Location:313 → 377
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
    cd16239
    Location:198 → 310
    EFh_SPARC_TICN3; EF-hand, extracellular calcium-binding (EC) motif, found in testican-3 (TICN3)

  2. NM_001204352.2 → NP_001191281.1  testican-3 isoform 3

    See identical proteins and their annotated locations for NP_001191281.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks an exon, includes an alternate exon in the 5' coding region, and uses an alternate start codon, compared to variant 2. The encoded isoform (3) is shorter and has a distinct N-terminus, compared to isoform 2.
    Source sequence(s)
    AC020599, AK295015, BI603782
    Consensus CDS
    CCDS56344.1
    UniProtKB/TrEMBL
    B4DI52
    Related
    ENSP00000411344.2, ENST00000421836.6
    Conserved Domains (4) summary
    smart00280
    Location:89 → 132
    KAZAL; Kazal type serine protease inhibitors
    cd00191
    Location:265 → 329
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
    cd00252
    Location:149 → 268
    SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
    pfam10591
    Location:148 → 255
    SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region

  3. NM_001204353.1 → NP_001191282.1  testican-3 isoform 4

    See identical proteins and their annotated locations for NP_001191282.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, lacks two exons and uses a downstream, in-frame start codon, compared to variant 2. The encoded isoform (4) has a shorter N-terminus, compared to isoform 2.
    Source sequence(s)
    AC020599, AK295407
    Consensus CDS
    CCDS56343.1
    UniProtKB/TrEMBL
    B4DI52
    Related
    ENSP00000444789.1, ENST00000541354.5
    Conserved Domains (4) summary
    smart00280
    Location:20 → 63
    KAZAL; Kazal type serine protease inhibitors
    cd00191
    Location:196 → 260
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
    cd00252
    Location:80 → 199
    SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
    pfam10591
    Location:79 → 186
    SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region

  4. NM_001204354.2 → NP_001191283.1  testican-3 isoform 5

    See identical proteins and their annotated locations for NP_001191283.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) lacks two consecutive exons and uses a downstream, in-frame start codon, compared to variant 2. The encoded isoform (5) has a shorter N-terminus, compared to isoform 2.
    Source sequence(s)
    AC020599, AK091078, AK295414
    Consensus CDS
    CCDS75207.1
    UniProtKB/TrEMBL
    A0A0A0MTJ2, B4DI52
    Related
    ENSP00000441396.2, ENST00000535728.5
    Conserved Domains (4) summary
    smart00280
    Location:48 → 91
    KAZAL; Kazal type serine protease inhibitors
    cd00191
    Location:224 → 288
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
    cd00252
    Location:108 → 227
    SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
    pfam10591
    Location:107 → 214
    SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region

  5. NM_001204355.2 → NP_001191284.1  testican-3 isoform 6

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) lacks three consecutive coding exons and uses an alternate start codon, compared to variant 2. The encoded isoform (6) is shorter and has a distinct N-terminus, compared to isoform 2.
    Source sequence(s)
    AC020599, AK295281, BI603782
    UniProtKB/TrEMBL
    B4DI52
    Conserved Domains (4) summary
    smart00280
    Location:44 → 87
    KAZAL; Kazal type serine protease inhibitors
    cd00191
    Location:220 → 284
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
    cd00252
    Location:104 → 223
    SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
    pfam10591
    Location:103 → 210
    SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region

  6. NM_001204356.2 → NP_001191285.1  testican-3 isoform 7 precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) lacks two alternate in-frame exons compared to variant 2. The resulting isoform (7) has the same N- and C-termini but is shorter compared to isoform 2.
    Source sequence(s)
    AC020599, AK296291, BI603782
    Consensus CDS
    CCDS56346.1
    UniProtKB/TrEMBL
    B4DFW5
    Related
    ENSP00000426716.1, ENST00000510741.5
    Conserved Domains (3) summary
    smart00280
    Location:137 → 180
    KAZAL; Kazal type serine protease inhibitors
    cd00191
    Location:273 → 337
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
    cd00252
    Location:195 → 276
    SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...

  7. NM_001204358.2 → NP_001191287.1  testican-3 isoform 9 precursor

    See identical proteins and their annotated locations for NP_001191287.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) lacks an alternate in-frame exon and differs in the 3' UTR and coding sequence compared to variant 2. The resulting isoform (9, also known as N-TES) has a shorter and distinct C-terminus and lacks an alternate internal segment compared to isoform 2.
    Source sequence(s)
    AB056866, AC020599
    Consensus CDS
    CCDS56347.1
    UniProtKB/Swiss-Prot
    Q9BQ16
    Related
    ENSP00000426177.1, ENST00000512648.5
    Conserved Domains (3) summary
    smart00280
    Location:137 → 180
    KAZAL; Kazal type serine protease inhibitors
    cd00252
    Location:197 → 311
    SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
    pfam10591
    Location:196 → 303
    SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region

  8. NM_001251967.2 → NP_001238896.1  testican-3 isoform 11 precursor

    See identical proteins and their annotated locations for NP_001238896.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11) lacks four consecutive coding exons but maintains the reading frame, compared to variant 2. The encoded isoform (11) is shorter than isoform 2.
    Source sequence(s)
    AC020599, AK294637, BI603782
    Consensus CDS
    CCDS58931.1
    UniProtKB/TrEMBL
    B4DI52
    Related
    ENSP00000426318.1, ENST00000512681.5
    Conserved Domains (3) summary
    cd00191
    Location:218 → 282
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
    cd00252
    Location:102 → 221
    SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
    pfam10591
    Location:101 → 208
    SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region

  9. NM_016950.3 → NP_058646.2  testican-3 isoform 2 precursor

    See identical proteins and their annotated locations for NP_058646.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) encodes the longest isoform (2).
    Source sequence(s)
    AC020599, AY358973
    Consensus CDS
    CCDS54817.1
    UniProtKB/Swiss-Prot
    B2R7M7, B3KR67, B4DGK5, B4DHB4, B4DHV3, B4DI46, B4DJY3, E7EP61, F5H099, O75705, Q6UW53, Q96Q26, Q9BQ16
    UniProtKB/TrEMBL
    B4DFW5
    Related
    ENSP00000349677.3, ENST00000357154.7
    Conserved Domains (4) summary
    smart00280
    Location:140 → 183
    KAZAL; Kazal type serine protease inhibitors
    cd00191
    Location:316 → 380
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
    cd00252
    Location:200 → 319
    SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
    pfam10591
    Location:199 → 306
    SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    166733384..167234945 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017008258.2 → XP_016863747.1  testican-3 isoform X3

    UniProtKB/TrEMBL
    B4DFW5
    Related
    ENSP00000425570.1, ENST00000504953.5
    Conserved Domains (3) summary
    smart00280
    Location:137 → 180
    KAZAL; Kazal type serine protease inhibitors
    cd00191
    Location:313 → 377
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
    cd16239
    Location:198 → 310
    EFh_SPARC_TICN3; EF-hand, extracellular calcium-binding (EC) motif, found in testican-3 (TICN3)

  2. XM_011532018.2 → XP_011530320.1  testican-3 isoform X2

    See identical proteins and their annotated locations for XP_011530320.1

    UniProtKB/Swiss-Prot
    B2R7M7, B3KR67, B4DGK5, B4DHB4, B4DHV3, B4DI46, B4DJY3, E7EP61, F5H099, O75705, Q6UW53, Q96Q26, Q9BQ16
    UniProtKB/TrEMBL
    B4DFW5
    Related
    ENSP00000420920.1, ENST00000506886.5
    Conserved Domains (4) summary
    smart00280
    Location:140 → 183
    KAZAL; Kazal type serine protease inhibitors
    cd00191
    Location:316 → 380
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
    cd00252
    Location:200 → 319
    SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
    pfam10591
    Location:199 → 306
    SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region

  3. XM_017008257.2 → XP_016863746.1  testican-3 isoform X1

    UniProtKB/TrEMBL
    B4DFW5
    Related
    ENSP00000425502.1, ENST00000511269.5

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    170090608..170592260 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054350129.1 → XP_054206104.1  testican-3 isoform X3

  2. XM_054350128.1 → XP_054206103.1  testican-3 isoform X2

    UniProtKB/Swiss-Prot
    B2R7M7, B3KR67, B4DGK5, B4DHB4, B4DHV3, B4DI46, B4DJY3, E7EP61, F5H099, O75705, Q6UW53, Q96Q26, Q9BQ16

  3. XM_054350127.1 → XP_054206102.1  testican-3 isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001204359.1: Suppressed sequence

    Description
    NM_001204359.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9BQ16.2 GenPept UniProtKB/Swiss-Prot:Q9BQ16

Gene LinkOut

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