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PHF20L1 PHD finger protein 20 like 1 [ Homo sapiens (human) ]

Gene ID: 51105, updated on 16-Apr-2024

Summary

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Official Symbol
PHF20L1provided by HGNC
Official Full Name
PHD finger protein 20 like 1provided by HGNC
Primary source
HGNC:HGNC:24280
See related
Ensembl:ENSG00000129292 MIM:620050; AllianceGenome:HGNC:24280
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
URLC1; CGI-72; TDRD20B
Summary
Predicted to enable metal ion binding activity. Predicted to be involved in histone acetylation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of NSL complex. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thyroid (RPKM 8.3), testis (RPKM 4.7) and 25 other tissues See more
Orthologs
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Genomic context

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See PHF20L1 in Genome Data Viewer
Location:
8q24.22
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (132775388..132848807)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (133898574..133971990)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (133787634..133861052)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene dynein axonemal assembly factor 11 Neighboring gene Helicobacter pylori responsive 1 Neighboring gene uncharacterized LOC105375767 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr8:133699646-133700172 Neighboring gene transmembrane protein 71 Neighboring gene H3K27ac hESC enhancer GRCh37_chr8:133787363-133787864 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19559 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:133894667-133895168 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:133895169-133895668 Neighboring gene thyroglobulin Neighboring gene uncharacterized LOC105375768 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27992 Neighboring gene ribosomal protein L21 pseudogene 78

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. PHF20L1 mediates PAX2 expression to promote angiogenesis and liver metastasis in colorectal cancer through regulating HIC1. Zhu QC, et al. Biol Chem, 2022 Sep 27. PMID 35357096
  2. An insight into the promoter methylation of PHF20L1 and the gene association with metastasis in breast cancer. Sierra-Ramirez JA, et al. Adv Clin Exp Med, 2021 May. PMID 33847474
  3. PHF20L1 as a H3K27me2 reader coordinates with transcriptional repressors to promote breast tumorigenesis. Hou Y, et al. Sci Adv, 2020 Apr. PMID 32494608, Free PMC Article
  4. Tudor-domain protein PHF20L1 reads lysine methylated retinoblastoma tumour suppressor protein. Carr SM, et al. Cell Death Differ, 2017 Dec. PMID 28841214, Free PMC Article
  5. An integrated genomic analysis of Tudor domain-containing proteins identifies PHD finger protein 20-like 1 (PHF20L1) as a candidate oncogene in breast cancer. Jiang Y, et al. Mol Oncol, 2016 Feb. PMID 26588862, Free PMC Article

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Single-genome analysis reveals a heterogeneous association of the herpes simplex virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts.
    Title: Single-genome analysis reveals a heterogeneous association of the herpes simplex virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts.
  2. PHF20L1 mediates PAX2 expression to promote angiogenesis and liver metastasis in colorectal cancer through regulating HIC1.
    Title: PHF20L1 mediates PAX2 expression to promote angiogenesis and liver metastasis in colorectal cancer through regulating HIC1.
  3. PHF20L1 as a H3K27me2 reader coordinates with transcriptional repressors to promote breast tumorigenesis.
    Title: PHF20L1 as a H3K27me2 reader coordinates with transcriptional repressors to promote breast tumorigenesis.
  4. An insight into the promoter methylation of PHF20L1 and the gene association with metastasis in breast cancer.
    Title: An insight into the promoter methylation of PHF20L1 and the gene association with metastasis in breast cancer.
  5. associates with SOX2, antagonizes SOX2 ubiquitination and the sequential degradation induced by the MLL1/WDR5 complexes
    Title: PHF20L1 antagonizes SOX2 proteolysis triggered by the MLL1/WDR5 complexes.
  6. Data suggest that, in human ovarian teratocarcinoma cell line, methylation-dependent proteolysis of SOX2 is controlled by LSD1 and PHF20L1 via regulation of SET7 activity; these data are consistent with previous studies in mouse primary stem cells. (SOX2 = SRY-box 2 transcription factor; LSD1 = lysine demethylase-1A; PHF20L1 = PHD finger protein 20 like-1; SET7 = histone-lysine N-methyltransferase SETD7)
    Title: LSD1 demethylase and the methyl-binding protein PHF20L1 prevent SET7 methyltransferase-dependent proteolysis of the stem-cell protein SOX2.
  7. Authors find that the interplay between PHF20L1 and mono-methyl pRb is important for maintaining the integrity of a pRb-dependent G1-S-phase checkpoint. Results highlight the distinct roles that methyl-lysine readers have in regulating the biological activity of pRb.
    Title: Tudor-domain protein PHF20L1 reads lysine methylated retinoblastoma tumour suppressor protein.
  8. results demonstrated the oncogenic potential of PHF20L1 and its association with poor prognostic parameters in breast cancer.
    Title: An integrated genomic analysis of Tudor domain-containing proteins identifies PHD finger protein 20-like 1 (PHF20L1) as a candidate oncogene in breast cancer.
  9. Malignant brain tumor domain of PHF20L1 reads and controls enzyme levels of methylated DNMT1 in cells, thus representing a novel antagonist of DNMT1 degradation.
    Title: Methyllysine reader plant homeodomain (PHD) finger protein 20-like 1 (PHF20L1) antagonizes DNA (cytosine-5) methyltransferase 1 (DNMT1) proteasomal degradation.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC64923

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables methylation-dependent protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of proteasomal ubiquitin-dependent protein catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of protein catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of NSL complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleoplasm TAS
Traceable Author Statement
more info
  

General protein information

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Preferred Names
PHD finger protein 20-like protein 1
Names
tudor domain containing 20B
tudor domain-containing protein PHF20L1
up-regulated in lung cancer 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001277196.2 → NP_001264125.1  PHD finger protein 20-like protein 1 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (4) has the same N- and C-termini but is shorter compared to isoform 1. Variants 4 and 5 encode the same isoform (4).
    Source sequence(s)
    AF228727, AF230666, BC144654, DB498348
    Consensus CDS
    CCDS75791.1
    UniProtKB/TrEMBL
    A0A0A0MQS0
    Conserved Domains (5) summary
    cd04508
    Location:90 → 135
    TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
    cd15633
    Location:657 → 702
    PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
    pfam12618
    Location:184 → 291
    DUF3776; Protein of unknown function (DUF3776)
    pfam16660
    Location:292 → 388
    PHD20L1_u1; PHD finger protein 20-like protein 1
    cl17705
    Location:3 → 68
    MBT; mbt repeat

  2. NM_001362971.2 → NP_001349900.1  PHD finger protein 20-like protein 1 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AF228727, AF230666, BC144654, DB498348
    Consensus CDS
    CCDS75791.1
    UniProtKB/TrEMBL
    A0A0A0MQS0
    Related
    ENSP00000220847.8, ENST00000220847.8
    Conserved Domains (5) summary
    cd04508
    Location:90 → 135
    TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
    cd15633
    Location:657 → 702
    PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
    pfam12618
    Location:184 → 291
    DUF3776; Protein of unknown function (DUF3776)
    pfam16660
    Location:292 → 388
    PHD20L1_u1; PHD finger protein 20-like protein 1
    cl17705
    Location:3 → 68
    MBT; mbt repeat

  3. NM_016018.5 → NP_057102.4  PHD finger protein 20-like protein 1 isoform 1

    See identical proteins and their annotated locations for NP_057102.4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and it encodes the longest protein (isoform 1).
    Source sequence(s)
    AF230666, AK057961, BC002822, DA196349, DB498348
    Consensus CDS
    CCDS6367.2
    UniProtKB/Swiss-Prot
    A8MW92, A8MZC9, Q86U89, Q86W43, Q96BT0, Q9H702, Q9HBK3, Q9NYR3, Q9Y381
    Related
    ENSP00000378784.2, ENST00000395386.7
    Conserved Domains (5) summary
    cd04508
    Location:90 → 135
    TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
    cd15633
    Location:683 → 728
    PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
    pfam12618
    Location:210 → 317
    DUF3776; Protein of unknown function (DUF3776)
    pfam16660
    Location:318 → 383
    PHD20L1_u1; PHD finger protein 20-like protein 1
    cl17705
    Location:3 → 68
    MBT; mbt repeat

  4. NM_198513.2 → NP_940915.1  PHD finger protein 20-like protein 1 isoform 3

    See identical proteins and their annotated locations for NP_940915.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has multiple differences, compared to variant 1. The resulting protein (isoform 3) has a shorter and distinct C-terminus when it is compared to isoform 1.
    Source sequence(s)
    AI913146, AK023711, BC015211, DB498348
    Consensus CDS
    CCDS6368.1
    UniProtKB/TrEMBL
    A8MUE8
    Related
    ENSP00000338269.4, ENST00000337920.8
    Conserved Domains (2) summary
    cd20454
    Location:86 → 144
    Tudor_PHF20L1; Tudor domain found in PHD finger protein 20-like protein 1 (PHF20L1) and similar proteins
    cl17705
    Location:3 → 68
    MBT; mbt repeat

RNA

  1. NR_156424.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AF228727, AF230666, BC144654, DA557575, DB498348

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    132775388..132848807
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011517075.1 → XP_011515377.1  PHD finger protein 20-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011515377.1

    Conserved Domains (5) summary
    cd04508
    Location:90 → 135
    TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
    cd15633
    Location:688 → 733
    PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
    pfam12618
    Location:214 → 322
    DUF3776; Protein of unknown function (DUF3776)
    pfam16660
    Location:323 → 388
    PHD20L1_u1; PHD finger protein 20-like protein 1
    cl17705
    Location:3 → 68
    MBT; mbt repeat

  2. XM_011517077.1 → XP_011515379.1  PHD finger protein 20-like protein 1 isoform X3

    Conserved Domains (5) summary
    cd04508
    Location:90 → 135
    TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
    cd15633
    Location:687 → 732
    PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
    pfam12618
    Location:214 → 321
    DUF3776; Protein of unknown function (DUF3776)
    pfam16660
    Location:322 → 387
    PHD20L1_u1; PHD finger protein 20-like protein 1
    cl17705
    Location:3 → 68
    MBT; mbt repeat

  3. XM_011517078.1 → XP_011515380.1  PHD finger protein 20-like protein 1 isoform X5

    Conserved Domains (5) summary
    cd04508
    Location:90 → 135
    TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
    cd15633
    Location:684 → 729
    PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
    pfam12618
    Location:210 → 318
    DUF3776; Protein of unknown function (DUF3776)
    pfam16660
    Location:319 → 384
    PHD20L1_u1; PHD finger protein 20-like protein 1
    cl17705
    Location:3 → 68
    MBT; mbt repeat

  4. XM_047421819.1 → XP_047277775.1  PHD finger protein 20-like protein 1 isoform X6

  5. XM_011517079.1 → XP_011515381.1  PHD finger protein 20-like protein 1 isoform X7

    Conserved Domains (5) summary
    cd04508
    Location:90 → 135
    TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
    cd15633
    Location:683 → 728
    PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
    pfam12618
    Location:210 → 317
    DUF3776; Protein of unknown function (DUF3776)
    pfam16660
    Location:318 → 383
    PHD20L1_u1; PHD finger protein 20-like protein 1
    cl17705
    Location:3 → 68
    MBT; mbt repeat

  6. XM_011517080.1 → XP_011515382.1  PHD finger protein 20-like protein 1 isoform X9

    Conserved Domains (5) summary
    cd04508
    Location:90 → 135
    TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
    cd15633
    Location:658 → 703
    PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
    pfam12618
    Location:184 → 292
    DUF3776; Protein of unknown function (DUF3776)
    pfam16660
    Location:293 → 358
    PHD20L1_u1; PHD finger protein 20-like protein 1
    cl17705
    Location:3 → 68
    MBT; mbt repeat

  7. XM_047421823.1 → XP_047277779.1  PHD finger protein 20-like protein 1 isoform X10

    UniProtKB/TrEMBL
    F8W9L8
    Related
    ENSP00000378788.2, ENST00000395390.6

  8. XM_011517081.1 → XP_011515383.1  PHD finger protein 20-like protein 1 isoform X11

    Conserved Domains (5) summary
    cd04508
    Location:90 → 135
    TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
    cd15633
    Location:657 → 702
    PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
    pfam12618
    Location:184 → 291
    DUF3776; Protein of unknown function (DUF3776)
    pfam16660
    Location:292 → 357
    PHD20L1_u1; PHD finger protein 20-like protein 1
    cl17705
    Location:3 → 68
    MBT; mbt repeat

  9. XM_011517076.1 → XP_011515378.1  PHD finger protein 20-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011515378.1

    Conserved Domains (5) summary
    cd04508
    Location:90 → 135
    TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
    cd15633
    Location:688 → 733
    PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
    pfam12618
    Location:214 → 322
    DUF3776; Protein of unknown function (DUF3776)
    pfam16660
    Location:323 → 388
    PHD20L1_u1; PHD finger protein 20-like protein 1
    cl17705
    Location:3 → 68
    MBT; mbt repeat

  10. XM_047421815.1 → XP_047277771.1  PHD finger protein 20-like protein 1 isoform X2

  11. XM_047421816.1 → XP_047277772.1  PHD finger protein 20-like protein 1 isoform X3

  12. XM_047421817.1 → XP_047277773.1  PHD finger protein 20-like protein 1 isoform X4

  13. XM_047421818.1 → XP_047277774.1  PHD finger protein 20-like protein 1 isoform X5

  14. XM_047421820.1 → XP_047277776.1  PHD finger protein 20-like protein 1 isoform X6

  15. XM_017013509.1 → XP_016868998.1  PHD finger protein 20-like protein 1 isoform X7

    Conserved Domains (5) summary
    cd04508
    Location:90 → 135
    TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
    cd15633
    Location:683 → 728
    PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
    pfam12618
    Location:210 → 317
    DUF3776; Protein of unknown function (DUF3776)
    pfam16660
    Location:318 → 383
    PHD20L1_u1; PHD finger protein 20-like protein 1
    cl17705
    Location:3 → 68
    MBT; mbt repeat

  16. XM_047421821.1 → XP_047277777.1  PHD finger protein 20-like protein 1 isoform X8

    UniProtKB/Swiss-Prot
    A8MW92, A8MZC9, Q86U89, Q86W43, Q96BT0, Q9H702, Q9HBK3, Q9NYR3, Q9Y381
    Related
    ENSP00000482945.1, ENST00000622263.4

  17. XM_017013510.1 → XP_016868999.1  PHD finger protein 20-like protein 1 isoform X9

    Conserved Domains (5) summary
    cd04508
    Location:90 → 135
    TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
    cd15633
    Location:658 → 703
    PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
    pfam12618
    Location:184 → 292
    DUF3776; Protein of unknown function (DUF3776)
    pfam16660
    Location:293 → 358
    PHD20L1_u1; PHD finger protein 20-like protein 1
    cl17705
    Location:3 → 68
    MBT; mbt repeat

  18. XM_047421822.1 → XP_047277778.1  PHD finger protein 20-like protein 1 isoform X10

    UniProtKB/TrEMBL
    F8W9L8

  19. XM_017013511.1 → XP_016869000.1  PHD finger protein 20-like protein 1 isoform X11

    Conserved Domains (5) summary
    cd04508
    Location:90 → 135
    TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
    cd15633
    Location:657 → 702
    PHD_PHF20L1; PHD finger found in PHD finger protein 20-like protein 1 (P20L1)
    pfam12618
    Location:184 → 291
    DUF3776; Protein of unknown function (DUF3776)
    pfam16660
    Location:292 → 357
    PHD20L1_u1; PHD finger protein 20-like protein 1
    cl17705
    Location:3 → 68
    MBT; mbt repeat

  20. XM_011517088.1 → XP_011515390.1  PHD finger protein 20-like protein 1 isoform X13

    See identical proteins and their annotated locations for XP_011515390.1

    Conserved Domains (4) summary
    cd04508
    Location:90 → 135
    TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
    pfam12618
    Location:214 → 322
    DUF3776; Protein of unknown function (DUF3776)
    pfam16660
    Location:323 → 388
    PHD20L1_u1; PHD finger protein 20-like protein 1
    cl17705
    Location:3 → 68
    MBT; mbt repeat

  21. XM_017013516.1 → XP_016869005.1  PHD finger protein 20-like protein 1 isoform X14

    UniProtKB/TrEMBL
    A0A0A8K9A6
    Related
    ENST00000315808.14
    Conserved Domains (4) summary
    cd04508
    Location:90 → 135
    TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
    pfam12618
    Location:210 → 317
    DUF3776; Protein of unknown function (DUF3776)
    pfam16660
    Location:318 → 383
    PHD20L1_u1; PHD finger protein 20-like protein 1
    cl17705
    Location:3 → 68
    MBT; mbt repeat

  22. XM_047421825.1 → XP_047277781.1  PHD finger protein 20-like protein 1 isoform X15

  23. XM_047421826.1 → XP_047277782.1  PHD finger protein 20-like protein 1 isoform X16

  24. XM_047421827.1 → XP_047277783.1  PHD finger protein 20-like protein 1 isoform X16

  25. XM_017013517.2 → XP_016869006.1  PHD finger protein 20-like protein 1 isoform X17

    UniProtKB/TrEMBL
    A8MUE8
    Related
    ENSP00000378777.1, ENST00000395379.5
    Conserved Domains (2) summary
    cd20454
    Location:86 → 144
    Tudor_PHF20L1; Tudor domain found in PHD finger protein 20-like protein 1 (PHF20L1) and similar proteins
    cl17705
    Location:3 → 68
    MBT; mbt repeat

  26. XM_047421824.1 → XP_047277780.1  PHD finger protein 20-like protein 1 isoform X12

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    133898574..133971990
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054360553.1 → XP_054216528.1  PHD finger protein 20-like protein 1 isoform X1

  2. XM_054360556.1 → XP_054216531.1  PHD finger protein 20-like protein 1 isoform X3

  3. XM_054360559.1 → XP_054216534.1  PHD finger protein 20-like protein 1 isoform X5

  4. XM_054360561.1 → XP_054216536.1  PHD finger protein 20-like protein 1 isoform X6

  5. XM_054360563.1 → XP_054216538.1  PHD finger protein 20-like protein 1 isoform X7

  6. XM_054360566.1 → XP_054216541.1  PHD finger protein 20-like protein 1 isoform X9

  7. XM_054360569.1 → XP_054216544.1  PHD finger protein 20-like protein 1 isoform X10

    UniProtKB/TrEMBL
    F8W9L8

  8. XM_054360570.1 → XP_054216545.1  PHD finger protein 20-like protein 1 isoform X11

  9. XM_054360554.1 → XP_054216529.1  PHD finger protein 20-like protein 1 isoform X1

  10. XM_054360555.1 → XP_054216530.1  PHD finger protein 20-like protein 1 isoform X2

  11. XM_054360557.1 → XP_054216532.1  PHD finger protein 20-like protein 1 isoform X3

  12. XM_054360558.1 → XP_054216533.1  PHD finger protein 20-like protein 1 isoform X4

  13. XM_054360560.1 → XP_054216535.1  PHD finger protein 20-like protein 1 isoform X5

  14. XM_054360562.1 → XP_054216537.1  PHD finger protein 20-like protein 1 isoform X6

  15. XM_054360564.1 → XP_054216539.1  PHD finger protein 20-like protein 1 isoform X7

  16. XM_054360565.1 → XP_054216540.1  PHD finger protein 20-like protein 1 isoform X8

    UniProtKB/Swiss-Prot
    A8MW92, A8MZC9, Q86U89, Q86W43, Q96BT0, Q9H702, Q9HBK3, Q9NYR3, Q9Y381

  17. XM_054360567.1 → XP_054216542.1  PHD finger protein 20-like protein 1 isoform X9

  18. XM_054360568.1 → XP_054216543.1  PHD finger protein 20-like protein 1 isoform X10

    UniProtKB/TrEMBL
    F8W9L8

  19. XM_054360571.1 → XP_054216546.1  PHD finger protein 20-like protein 1 isoform X11

  20. XM_054360573.1 → XP_054216548.1  PHD finger protein 20-like protein 1 isoform X13

  21. XM_054360574.1 → XP_054216549.1  PHD finger protein 20-like protein 1 isoform X14

    UniProtKB/TrEMBL
    A0A0A8K9A6

  22. XM_054360575.1 → XP_054216550.1  PHD finger protein 20-like protein 1 isoform X15

  23. XM_054360576.1 → XP_054216551.1  PHD finger protein 20-like protein 1 isoform X16

  24. XM_054360577.1 → XP_054216552.1  PHD finger protein 20-like protein 1 isoform X16

  25. XM_054360578.1 → XP_054216553.1  PHD finger protein 20-like protein 1 isoform X17

  26. XM_054360572.1 → XP_054216547.1  PHD finger protein 20-like protein 1 isoform X12

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_024878.1: Suppressed sequence

    Description
    NM_024878.1: This RefSeq was permanently suppressed because it represents actually 5' partial CDS and its 5' sequence was intronic sequence.

  2. NM_032205.3: Suppressed sequence

    Description
    NM_032205.3: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A8MW92.2 GenPept UniProtKB/Swiss-Prot:A8MW92

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