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GMPS guanine monophosphate synthase [ Bos taurus (cattle) ]

Gene ID: 511200, updated on 3-Apr-2024

Summary

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Official Symbol
GMPSprovided by VGNC
Official Full Name
guanine monophosphate synthaseprovided by VGNC
Primary source
VGNC:VGNC:29443
See related
BGD:BT29695; Ensembl:ENSBTAG00000013013
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 1 NC_037328.1 (111732897..111804777, complement)

Chromosome 1 - NC_037328.1Genomic Context describing neighboring genes Neighboring gene vomeronasal type-2 receptor 1-like Neighboring gene vomeronasal type-2 receptor 1-like Neighboring gene uncharacterized LOC132345804 Neighboring gene tubulin-folding cofactor B-like Neighboring gene uncharacterized LOC132345801 Neighboring gene uncharacterized LOC112447738 Neighboring gene solute carrier family 33 member 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GMP synthase (glutamine-hydrolyzing) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GMP synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in GMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
GMP synthase [glutamine-hydrolyzing]
Names
guanine monophosphate synthetase
NP_001193365.1
XP_024835606.1
XP_024835638.1
XP_059734468.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001206436.1 → NP_001193365.1  GMP synthase [glutamine-hydrolyzing]

    See identical proteins and their annotated locations for NP_001193365.1

    Status: VALIDATED

    Source sequence(s)
    BC111273
    UniProtKB/TrEMBL
    A0A3Q1LR60, Q2T9U0
    Related
    ENSBTAP00000057515.1, ENSBTAT00000069914.1
    Conserved Domains (3) summary
    cd01742
    Location:34 → 213
    GATase1_GMP_Synthase; Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase
    PRK00074
    Location:34 → 699
    guaA; GMP synthase; Reviewed
    cd01997
    Location:244 → 698
    GMP_synthase_C; The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037328.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    111732897..111804777 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059878485.1 → XP_059734468.1  GMP synthase [glutamine-hydrolyzing] isoform X2

    Related
    ENSBTAP00000077935.1, ENSBTAT00000122988.1

  2. XM_024979838.2 → XP_024835606.1  GMP synthase [glutamine-hydrolyzing] isoform X1

    UniProtKB/TrEMBL
    F1MC86, Q2T9U0
    Related
    ENSBTAP00000064263.2, ENSBTAT00000084984.2
    Conserved Domains (1) summary
    cl27749
    Location:28 → 693
    GATase; Glutamine amidotransferase class-I

  3. XM_024979870.2 → XP_024835638.1  GMP synthase [glutamine-hydrolyzing] isoform X3

    UniProtKB/TrEMBL
    Q2T9U0
    Conserved Domains (1) summary
    cl27749
    Location:20 → 685
    GATase; Glutamine amidotransferase class-I
Nucleotide Protein Strain
Heading Accession and Version

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