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POU2F1 POU class 2 homeobox 1 [ Bos taurus (cattle) ]

Gene ID: 512840, updated on 3-Apr-2024

Summary

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Official Symbol
POU2F1provided by VGNC
Official Full Name
POU class 2 homeobox 1provided by VGNC
Primary source
VGNC:VGNC:33174
See related
Ensembl:ENSBTAG00000024534
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (1269627..1482009, complement)

Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene cellular repressor of E1A stimulated genes 1 Neighboring gene CD247 molecule Neighboring gene large ribosomal subunit protein uL11-like Neighboring gene dynactin subunit 5-like Neighboring gene serine/threonine/tyrosine interacting like 2 Neighboring gene glycoprotein A33

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The role of oct-1 in the regulation of tracheal antimicrobial peptide (TAP) and lingual antimicrobial peptide (LAP) expression in bovine mammary epithelial cells. Yang J, et al. Immunogenetics, 2011 Nov. PMID 21674298
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The results from this study clearly demonstrate the involvement of octamer transcription factor-1 in the regulation of tracheal antimicrobial peptide and lingual antimicrobial peptide expression.
    Title: The role of oct-1 in the regulation of tracheal antimicrobial peptide (TAP) and lingual antimicrobial peptide (LAP) expression in bovine mammary epithelial cells.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC142534

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
POU domain, class 2, transcription factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001075582.2 → NP_001069050.1  POU domain, class 2, transcription factor 1

    See identical proteins and their annotated locations for NP_001069050.1

    Status: PROVISIONAL

    Source sequence(s)
    BC120288
    UniProtKB/TrEMBL
    A0A3Q1M3H3, Q0VC94
    Related
    ENSBTAP00000034020.3, ENSBTAT00000034119.4
    Conserved Domains (2) summary
    smart00352
    Location:292 → 366
    POU; Found in Pit-Oct-Unc transcription factors
    pfam00046
    Location:396 → 449
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    1269627..1482009 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024987873.2 → XP_024843641.2  POU domain, class 2, transcription factor 1 isoform X3

  2. XM_015461140.3 → XP_015316626.2  POU domain, class 2, transcription factor 1 isoform X3

  3. XM_015461135.3 → XP_015316621.2  POU domain, class 2, transcription factor 1 isoform X2

  4. XM_005203424.5 → XP_005203481.2  POU domain, class 2, transcription factor 1 isoform X1

    Related
    ENSBTAP00000085966.1, ENSBTAT00000111363.1

  5. XM_005203427.5 → XP_005203484.1  POU domain, class 2, transcription factor 1 isoform X5

    See identical proteins and their annotated locations for XP_005203484.1

    UniProtKB/TrEMBL
    A0A3Q1M3H3, A0A3Q1M487
    Related
    ENSBTAP00000064680.2, ENSBTAT00000086603.2
    Conserved Domains (2) summary
    smart00352
    Location:280 → 354
    POU; Found in Pit-Oct-Unc transcription factors
    pfam00046
    Location:384 → 437
    Homeobox; Homeobox domain

  6. XM_059883669.1 → XP_059739652.1  POU domain, class 2, transcription factor 1 isoform X5

    UniProtKB/TrEMBL
    A0A3Q1M487

  7. XM_059883656.1 → XP_059739639.1  POU domain, class 2, transcription factor 1 isoform X4

    UniProtKB/TrEMBL
    F1MMF9
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.