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FBP1 fructose-bisphosphatase 1 [ Bos taurus (cattle) ]

Gene ID: 513483, updated on 22-Aug-2021

Summary

Official Symbol
FBP1provided by VGNC
Official Full Name
fructose-bisphosphatase 1provided by VGNC
Primary source
VGNC:VGNC:28887
See related
BGD:BT11723; Ensembl:ENSBTAG00000009733
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
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Genomic context

See FBP1 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
7
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 8 NC_037335.1 (81068093..81098919, complement)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 8 AC_000165.1 (82460863..82491694, complement)

Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene CTD nuclear envelope phosphatase 1 pseudogene Neighboring gene fructose-bisphosphatase 2 Neighboring gene aminopeptidase O (putative) Neighboring gene microRNA mir-2475 Neighboring gene microRNA mir-23b

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Homology

Clone Names

  • MGC128145

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables AMP binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables RNA polymerase II-specific DNA-binding transcription factor binding IEA
Inferred from Electronic Annotation
more info
 
enables fructose 1,6-bisphosphate 1-phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables identical protein binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables metal ion binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables monosaccharide binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in cellular response to magnesium ion ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cellular response to xenobiotic stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in dephosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in fructose 6-phosphate metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in gluconeogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in gluconeogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of Ras protein signal transduction ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of cell growth ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of glycolytic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of gluconeogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cytosol ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
fructose-1,6-bisphosphatase 1
Names
D-fructose-1,6-bisphosphate 1-phosphohydrolase 1
FBPase 1
liver FBPase
NP_001029619.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034447.2NP_001029619.1  fructose-1,6-bisphosphatase 1

    See identical proteins and their annotated locations for NP_001029619.1

    Status: PROVISIONAL

    Source sequence(s)
    BC102974
    UniProtKB/Swiss-Prot
    Q3SZB7
    Related
    ENSBTAP00000012835.2, ENSBTAT00000012835.3
    Conserved Domains (1) summary
    cd00354
    Location:18332
    FBPase; Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1, ...

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037335.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    81068093..81098919 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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