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RASGEF1A RasGEF domain family member 1A [ Bos taurus (cattle) ]

Gene ID: 514877, updated on 3-Apr-2024

Summary

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Official Symbol
RASGEF1Aprovided by VGNC
Official Full Name
RasGEF domain family member 1Aprovided by VGNC
Primary source
VGNC:VGNC:33743
See related
BGD:BT27842; Ensembl:ENSBTAG00000006870
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 28
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 28 NC_037355.1 (13585698..13631018, complement)

Chromosome 28 - NC_037355.1Genomic Context describing neighboring genes Neighboring gene protein lin-28 homolog A-like Neighboring gene ret proto-oncogene Neighboring gene chondroitin sulfate N-acetylgalactosaminyltransferase 2 Neighboring gene uncharacterized LOC132344126 Neighboring gene FXYD domain containing ion transport regulator 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037355.1 Chromosome 28 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
  2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ras-GEF domain-containing family member 1A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001015601.1 → NP_001015601.1  ras-GEF domain-containing family member 1A

    See identical proteins and their annotated locations for NP_001015601.1

    Status: PROVISIONAL

    Source sequence(s)
    BT020843
    UniProtKB/TrEMBL
    A0A3Q1N010, F1MYT5, Q5E9S7
    Related
    ENSBTAP00000009038.7, ENSBTAT00000009038.7
    Conserved Domains (2) summary
    cd06224
    Location:25 → 140
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    smart00147
    Location:190 → 438
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037355.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    13585698..13631018 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059882502.1 → XP_059738485.1  ras-GEF domain-containing family member 1A isoform X4

  2. XM_059882500.1 → XP_059738483.1  ras-GEF domain-containing family member 1A isoform X2

  3. XM_059882499.1 → XP_059738482.1  ras-GEF domain-containing family member 1A isoform X1

  4. XM_059882501.1 → XP_059738484.1  ras-GEF domain-containing family member 1A isoform X2

  5. XM_059882503.1 → XP_059738486.1  ras-GEF domain-containing family member 1A isoform X5

  6. XM_005226256.5 → XP_005226313.1  ras-GEF domain-containing family member 1A isoform X3

    See identical proteins and their annotated locations for XP_005226313.1

    UniProtKB/TrEMBL
    A0A3Q1N010, A0A3S5ZPI5
    Related
    ENSBTAP00000065647.2, ENSBTAT00000076538.2
    Conserved Domains (2) summary
    cd06224
    Location:56 → 183
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    pfam00617
    Location:224 → 418
    RasGEF; RasGEF domain
Nucleotide Protein Strain
Heading Accession and Version

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