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EIF4E2 eukaryotic translation initiation factor 4E family member 2 [ Bos taurus (cattle) ]

Gene ID: 519920, updated on 3-Apr-2024

Summary

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Official Symbol
EIF4E2provided by VGNC
Official Full Name
eukaryotic translation initiation factor 4E family member 2provided by VGNC
Primary source
VGNC:VGNC:28410
See related
BGD:BT27983; Ensembl:ENSBTAG00000010598
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (120187397..120218347)

Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene cholinergic receptor nicotinic delta subunit Neighboring gene uncharacterized LOC112443174 Neighboring gene cholinergic receptor nicotinic gamma subunit Neighboring gene uncharacterized LOC101906781 Neighboring gene inward rectifier potassium channel 13-like Neighboring gene polyhomeotic homolog 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC152103

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA 7-methylguanosine cap binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in translational initiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of eukaryotic translation initiation factor 4F complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
eukaryotic translation initiation factor 4E type 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001075795.2 → NP_001069263.1  eukaryotic translation initiation factor 4E type 2 isoform 1

    See identical proteins and their annotated locations for NP_001069263.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the shorter isoform (1).
    Source sequence(s)
    BC122831, NKLS02000002
    UniProtKB/TrEMBL
    A0A3Q1MRS1, Q0II31
    Related
    ENSBTAP00000067250.1, ENSBTAT00000070208.1
    Conserved Domains (1) summary
    pfam01652
    Location:55 → 214
    IF4E; Eukaryotic initiation factor 4E

  2. NM_001206416.1 → NP_001193345.1  eukaryotic translation initiation factor 4E type 2 isoform 2

    See identical proteins and their annotated locations for NP_001193345.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice pattern in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (2) has a longer and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    EH132414, EV682356, EV746051
    UniProtKB/TrEMBL
    A0A3Q1LSC2, A0A3Q1MRS1
    Related
    ENSBTAP00000049866.3, ENSBTAT00000055491.3
    Conserved Domains (1) summary
    pfam01652
    Location:55 → 214
    IF4E; Eukaryotic initiation factor 4E

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    120187397..120218347
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010802425.2 → XP_010800727.1  eukaryotic translation initiation factor 4E type 2 isoform X4

    See identical proteins and their annotated locations for XP_010800727.1

    UniProtKB/TrEMBL
    A0A3Q1MRS1
    Related
    ENSBTAP00000101207.1, ENSBTAT00000116679.1
    Conserved Domains (1) summary
    pfam01652
    Location:55 → 214
    IF4E; Eukaryotic initiation factor 4E

  2. XM_059874538.1 → XP_059730521.1  eukaryotic translation initiation factor 4E type 2 isoform X3

  3. XM_059874537.1 → XP_059730520.1  eukaryotic translation initiation factor 4E type 2 isoform X2

  4. XM_059874534.1 → XP_059730517.1  eukaryotic translation initiation factor 4E type 2 isoform X1

    Related
    ENSBTAP00000059919.2, ENSBTAT00000084173.2
Nucleotide Protein Strain
Heading Accession and Version

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