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FH fumarate hydratase [ Bos taurus (cattle) ]

Gene ID: 520260, updated on 11-Apr-2024

Summary

Official Symbol
FHprovided by VGNC
Official Full Name
fumarate hydrataseprovided by VGNC
Primary source
VGNC:VGNC:28995
See related
BGD:BT29191; Ensembl:ENSBTAG00000021688
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
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Genomic context

Location:
chromosome: 16
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 16 NC_037343.1 (35260924..35288031)

Chromosome 16 - NC_037343.1Genomic Context describing neighboring genes Neighboring gene opsin 3 Neighboring gene kynurenine 3-monooxygenase Neighboring gene ADP-ribosylation factor 1-like Neighboring gene regulator of G protein signaling 7 Neighboring gene E3 ubiquitin-protein ligase ARIH2-like

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037343.1 Chromosome 16 Reference ARS-UCD2.0 Primary Assembly

Pathways from PubChem

General gene information

Markers

Clone Names

  • MGC140701

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables fumarate hydratase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in fumarate metabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in malate metabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of tricarboxylic acid cycle heteromeric enzyme complex IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
fumarate hydratase, mitochondrial
NP_001069271.1
XP_059731382.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001075803.2NP_001069271.1  fumarate hydratase, mitochondrial

    See identical proteins and their annotated locations for NP_001069271.1

    Status: PROVISIONAL

    Source sequence(s)
    BC118450
    UniProtKB/TrEMBL
    A0A3Q1MSL5, Q148D3
    Related
    ENSBTAP00000028902.4, ENSBTAT00000028902.5
    Conserved Domains (2) summary
    cd01362
    Location:51506
    Fumarase_classII; Class II fumarases
    PRK00485
    Location:49510
    fumC; fumarate hydratase; Reviewed

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037343.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    35260924..35288031
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059875399.1XP_059731382.1  fumarate hydratase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LY08
    Related
    ENSBTAP00000060467.1, ENSBTAT00000084620.2