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Pbk PDZ binding kinase [ Mus musculus (house mouse) ]

Gene ID: 52033, updated on 23-Jun-2021

Summary

Official Symbol
Pbkprovided by MGI
Official Full Name
PDZ binding kinaseprovided by MGI
Primary source
MGI:MGI:1289156
See related
Ensembl:ENSMUSG00000022033
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TO; TOPK; AW538537; D14Ertd732; D14Ertd732e; 2810434B10Rik
Expression
Biased expression in CNS E11.5 (RPKM 25.9), liver E14 (RPKM 15.6) and 10 other tissues See more
Orthologs
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Genomic context

See Pbk in Genome Data Viewer
Location:
14 D1; 14 34.36 cM
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (66043360..66055271)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (65805911..65817822)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (66424748..66436659)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53863 Neighboring gene scavenger receptor class A, member 5 Neighboring gene establishment of sister chromatid cohesion N-acetyltransferase 2 Neighboring gene coiled-coil domain containing 25

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (1)  1 citation
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables MAP kinase kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein serine/threonine kinase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
lymphokine-activated killer T-cell-originated protein kinase
Names
MAPKK-like protein kinase
T-LAK cell-originated protein kinase
NP_075698.1
XP_006519320.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023209.2NP_075698.1  lymphokine-activated killer T-cell-originated protein kinase

    See identical proteins and their annotated locations for NP_075698.1

    Status: PROVISIONAL

    Source sequence(s)
    AB041882
    Consensus CDS
    CCDS27215.1
    UniProtKB/Swiss-Prot
    Q9JJ78
    Related
    ENSMUSP00000022612.4, ENSMUST00000022612.10
    Conserved Domains (1) summary
    cd14001
    Location:31318
    PKc_TOPK; Catalytic domain of the Dual-specificity protein kinase, Lymphokine-activated killer T-cell-originated protein kinase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    66043360..66055271
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006519257.5XP_006519320.1  lymphokine-activated killer T-cell-originated protein kinase isoform X1

    See identical proteins and their annotated locations for XP_006519320.1

    UniProtKB/Swiss-Prot
    Q9JJ78
    Conserved Domains (1) summary
    cd14001
    Location:31318
    PKc_TOPK; Catalytic domain of the Dual-specificity protein kinase, Lymphokine-activated killer T-cell-originated protein kinase
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