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Ccdc69 coiled-coil domain containing 69 [ Mus musculus (house mouse) ]

Gene ID: 52570, updated on 21-Apr-2024

Summary

Official Symbol
Ccdc69provided by MGI
Official Full Name
coiled-coil domain containing 69provided by MGI
Primary source
MGI:MGI:1196234
See related
Ensembl:ENSMUSG00000049588 AllianceGenome:MGI:1196234
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D11Ertd461e; 2210021E03Rik
Summary
Predicted to enable microtubule binding activity. Predicted to be involved in spindle midzone assembly. Predicted to be located in spindle midzone. Predicted to be active in nucleus. Predicted to colocalize with cytoplasm. Orthologous to human CCDC69 (coiled-coil domain containing 69). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in bladder adult (RPKM 8.4), thymus adult (RPKM 3.9) and 16 other tissues See more
Orthologs
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Genomic context

Location:
11 B1.3; 11 32.13 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (54940559..54969608, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (55049733..55078666, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene TNFAIP3 interacting protein 1 Neighboring gene STARR-positive B cell enhancer ABC_E1824 Neighboring gene 40S ribosomal protein S11-like Neighboring gene STARR-seq mESC enhancer starr_29522 Neighboring gene STARR-seq mESC enhancer starr_29523 Neighboring gene annexin A6 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:54836566-54836859 Neighboring gene predicted gene, 19911 Neighboring gene STARR-seq mESC enhancer starr_29527 Neighboring gene STARR-positive B cell enhancer ABC_E161 Neighboring gene STARR-positive B cell enhancer ABC_E8406 Neighboring gene GM2 ganglioside activator protein Neighboring gene ATP synthase peripheral stalk-membrane subunit b, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (2) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in spindle midzone assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
colocalizes_with cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in spindle midzone ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
coiled-coil domain-containing protein 69

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177471.4NP_803422.2  coiled-coil domain-containing protein 69

    See identical proteins and their annotated locations for NP_803422.2

    Status: VALIDATED

    Source sequence(s)
    AK008760, AK079810
    Consensus CDS
    CCDS36155.1
    UniProtKB/Swiss-Prot
    Q3TCJ8, Q8C515
    Related
    ENSMUSP00000054840.7, ENSMUST00000055040.13

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    54940559..54969608 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036156828.1XP_036012721.1  coiled-coil domain-containing protein 69 isoform X1

    UniProtKB/Swiss-Prot
    Q3TCJ8, Q8C515
  2. XM_011249125.2XP_011247427.1  coiled-coil domain-containing protein 69 isoform X1

    See identical proteins and their annotated locations for XP_011247427.1

    UniProtKB/Swiss-Prot
    Q3TCJ8, Q8C515