SRF serum response factor [Bos taurus (cattle)] - Gene

Summary

Official Symbol: SRFprovided by VGNC
Official Full Name: serum response factorprovided by VGNC
Primary source: VGNC:VGNC:35277
See related: BGD:BT10647; Ensembl:ENSBTAG00000012777
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 23

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	23	NC_037350.1 (16775130..16782650)

Chromosome 23 - NC_037350.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D6S2165 (e-PCR)
- UniSTS:65976

SRF_3467 (e-PCR)
- UniSTS:462571

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info	PubMed
enables serum response element binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: serum response factor

Names: serum response factor (c-fos serum response element-binding transcription factor)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001206016.1 → NP_001192945.1 serum response factor

See identical proteins and their annotated locations for NP_001192945.1

Status: PROVISIONAL

Source sequence(s)

NKLS02000023

UniProtKB/TrEMBL

E1BJP4

Related

ENSBTAP00000016981.3, ENSBTAT00000016981.5

Conserved Domains (1) summary

cd00266
Location:143 → 224

MADS_SRF_like; SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in ...