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Sec61a1 Sec61 alpha 1 subunit (S. cerevisiae) [ Mus musculus (house mouse) ]

Gene ID: 53421, updated on 23-Jun-2021

Summary

Official Symbol
Sec61a1provided by MGI
Official Full Name
Sec61 alpha 1 subunit (S. cerevisiae)provided by MGI
Primary source
MGI:MGI:1858417
See related
Ensembl:ENSMUSG00000030082
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Sec6; Sec61a; AA408394; AA410007
Expression
Ubiquitous expression in ovary adult (RPKM 174.0), large intestine adult (RPKM 157.8) and 28 other tissues See more
Orthologs
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Genomic context

See Sec61a1 in Genome Data Viewer
Location:
6; 6 D1
Exon count:
12
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (88480589..88495782, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (88503607..88518800, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (88453601..88468794, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene eukaryotic elongation factor, selenocysteine-tRNA-specific Neighboring gene predicted gene, 44264 Neighboring gene RuvB-like protein 1 Neighboring gene predicted gene, 46965 Neighboring gene kelch repeat and BTB (POZ) domain containing 12 Neighboring gene predicted gene, 26588 Neighboring gene monoglyceride lipase

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables calcium channel activity ISO
Inferred from Sequence Orthology
more info
 
enables protein transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ribosome binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ribosome binding IDA
Inferred from Direct Assay
more info
PubMed 
enables ribosome binding ISO
Inferred from Sequence Orthology
more info
 
enables signal sequence binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transmembrane transporter activity EXP
Inferred from Experiment
more info
PubMed 
Component Evidence Code Pubs
part_of Sec61 translocon complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in phagocytic vesicle membrane TAS
Traceable Author Statement
more info
 
located_in rough endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein transport protein Sec61 subunit alpha isoform 1
Names
SEC61, alpha subunit
protein transport protein Sec61 subunit alpha
sec61 alpha-1
transport protein sec61 alpha subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016906.4NP_058602.1  protein transport protein Sec61 subunit alpha isoform 1

    See identical proteins and their annotated locations for NP_058602.1

    Status: PROVISIONAL

    Source sequence(s)
    AC154038
    Consensus CDS
    CCDS39553.1
    UniProtKB/Swiss-Prot
    P61620
    Related
    ENSMUSP00000032168.6, ENSMUST00000032168.7
    Conserved Domains (1) summary
    PTZ00219
    Location:1471
    PTZ00219; Sec61 alpha subunit; Provisional

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    88480589..88495782 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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