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ZEB1 zinc finger E-box binding homeobox 1 [ Bos taurus (cattle) ]

Gene ID: 535183, updated on 5-Mar-2024

Summary

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Official Symbol
ZEB1provided by VGNC
Official Full Name
zinc finger E-box binding homeobox 1provided by VGNC
Primary source
VGNC:VGNC:37147
See related
BGD:BT26273; Ensembl:ENSBTAG00000020053
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
TCF8; deltaEF1
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 13
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 13 NC_037340.1 (33771235..33968002, complement)

Chromosome 13 - NC_037340.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132346890 Neighboring gene uncharacterized LOC104973755 Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like Neighboring gene small nucleolar RNA U109 Neighboring gene uncharacterized LOC104973760 Neighboring gene microRNA mir-11998 Neighboring gene uncharacterized LOC101903056 Neighboring gene zinc finger protein 438 Neighboring gene uncharacterized LOC132346891

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037340.1 Chromosome 13 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcription Factors ZEB1 and CREB Promote the Transcription of Bovine ABHD5 Gene. Wang X, et al. DNA Cell Biol, 2021 Feb. PMID 33332227
  2. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
  3. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
  4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Transcription Factors ZEB1 and CREB Promote the Transcription of Bovine ABHD5 Gene.
    Title: Transcription Factors ZEB1 and CREB Promote the Transcription of Bovine ABHD5 Gene.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in anatomical structure development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
zinc finger E-box-binding homeobox 1
Names
transcription factor 8 (represses interleukin 2 expression)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001206590.1 → NP_001193519.1  zinc finger E-box-binding homeobox 1

    Status: VALIDATED

    Source sequence(s)
    DAAA02035608, DAAA02035609, DAAA02035613, EE368340, EH141729
    UniProtKB/TrEMBL
    F1N264
    Related
    ENSBTAP00000038655.5, ENSBTAT00000038847.5
    Conserved Domains (5) summary
    smart00389
    Location:594 → 630
    HOX; Homeodomain
    COG5048
    Location:930 → 983
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:907 → 927
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:241 → 263
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:947 → 972
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037340.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    33771235..33968002 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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